mesotheliomas Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.|A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed) (Experimental Factor Ontology, EFO_0000588)
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Genes

30 genes co-occuring with the biological term mesotheliomas in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AXL AXL receptor tyrosine kinase
BIRC5 baculoviral IAP repeat containing 5
BMP6 bone morphogenetic protein 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
CA9 carbonic anhydrase IX
CALB2 calbindin 2
CALD1 caldesmon 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CLDN4 claudin 4
DES desmin
GATA3 GATA binding protein 3
GDF10 growth differentiation factor 10
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
MAPK1 mitogen-activated protein kinase 1
MLANA melan-A
MSLN mesothelin
MTAP methylthioadenosine phosphorylase
MUC1 mucin 1, cell surface associated
NAPSA napsin A aspartic peptidase
NES nestin
NF2 neurofibromin 2 (merlin)
PAX2 paired box 2
PAX8 paired box 8
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase