merbromin-3700 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the merbromin-3700 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM20 ADAM metallopeptidase domain 20
ADGRL3 adhesion G protein-coupled receptor L3
ANXA10 annexin A10
ARMCX4 armadillo repeat containing, X-linked 4
ATP10A ATPase, class V, type 10A
B9D1 B9 protein domain 1
BMP7 bone morphogenetic protein 7
C11ORF1 chromosome 11 open reading frame 1
C14ORF1 chromosome 14 open reading frame 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALML3 calmodulin-like 3
CAMKV CaM kinase-like vesicle-associated
CCDC57 coiled-coil domain containing 57
CCL16 chemokine (C-C motif) ligand 16
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
CLTA clathrin, light chain A
CNGA1 cyclic nucleotide gated channel alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DNAAF1 dynein, axonemal, assembly factor 1
EGR1 early growth response 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP3 fatty acid binding protein 3, muscle and heart
FGA fibrinogen alpha chain
FGFR2 fibroblast growth factor receptor 2
FZD5 frizzled class receptor 5
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GPR137 G protein-coupled receptor 137
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRM1 glutamate receptor, metabotropic 1
GRM8 glutamate receptor, metabotropic 8
HBE1 hemoglobin, epsilon 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IFI44L interferon-induced protein 44-like
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGSF1 immunoglobulin superfamily, member 1
INVS inversin
ITGA8 integrin, alpha 8
ITGB7 integrin, beta 7
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JUND jun D proto-oncogene
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIAA1467 KIAA1467
KIF5A kinesin family member 5A
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF3 Kruppel-like factor 3 (basic)
LARP4B La ribonucleoprotein domain family, member 4B
LGALS14 lectin, galactoside-binding, soluble, 14
MAGEC3 melanoma antigen family C3
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPPE1 metallophosphoesterase 1
MTRF1L mitochondrial translational release factor 1-like
MTSS1L metastasis suppressor 1-like
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
N4BP2L1 NEDD4 binding protein 2-like 1
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOTCH4 notch 4
OVOL1 ovo-like zinc finger 1
PCDHB3 protocadherin beta 3
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PLCE1 phospholipase C, epsilon 1
PLCH1 phospholipase C, eta 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PML promyelocytic leukemia
PRB4 proline-rich protein BstNI subfamily 4
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM48 RNA binding motif protein 48
RFXAP regulatory factor X-associated protein
RUNX1 runt-related transcription factor 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SSX1 synovial sarcoma, X breakpoint 1
SYN2 synapsin II
SYT2 synaptotagmin II
TBC1D30 TBC1 domain family, member 30
TM4SF4 transmembrane 4 L six family member 4
TMEM259 transmembrane protein 259
TNS1 tensin 1
TPM1 tropomyosin 1 (alpha)
TRIM10 tripartite motif containing 10
TRIM3 tripartite motif containing 3
TRIO trio Rho guanine nucleotide exchange factor
TSPAN9 tetraspanin 9
WNT6 wingless-type MMTV integration site family, member 6
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZNF222 zinc finger protein 222
ZNF43 zinc finger protein 43
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACSS3 acyl-CoA synthetase short-chain family member 3
ADGRL2 adhesion G protein-coupled receptor L2
AGMAT agmatine ureohydrolase (agmatinase)
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ATAD5 ATPase family, AAA domain containing 5
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BICC1 BicC family RNA binding protein 1
C1ORF105 chromosome 1 open reading frame 105
CA9 carbonic anhydrase IX
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCDC121 coiled-coil domain containing 121
CCDC186 coiled-coil domain containing 186
CCDC71 coiled-coil domain containing 71
CD3D CD3d molecule, delta (CD3-TCR complex)
CD80 CD80 molecule
CDHR2 cadherin-related family member 2
CEP41 centrosomal protein 41kDa
CFAP69 cilia and flagella associated protein 69
CHEK2 checkpoint kinase 2
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLDN11 claudin 11
CNTN1 contactin 1
CPB1 carboxypeptidase B1 (tissue)
CUZD1 CUB and zona pellucida-like domains 1
DIO3 deiodinase, iodothyronine, type III
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ENO3 enolase 3 (beta, muscle)
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ETV6 ets variant 6
EXD3 exonuclease 3'-5' domain containing 3
FAM189A2 family with sequence similarity 189, member A2
FBXO46 F-box protein 46
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GALK1 galactokinase 1
GBP2 guanylate binding protein 2, interferon-inducible
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR21 G protein-coupled receptor 21
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF2I general transcription factor IIi
IFI6 interferon, alpha-inducible protein 6
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCTD17 potassium channel tetramerization domain containing 17
KIF13A kinesin family member 13A
KLHL25 kelch-like family member 25
KRT17 keratin 17, type I
KRT86 keratin 86, type II
LRP2 low density lipoprotein receptor-related protein 2
LYPD3 LY6/PLAUR domain containing 3
MAGEA5 melanoma antigen family A5
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MILR1 mast cell immunoglobulin-like receptor 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTHFSD methenyltetrahydrofolate synthetase domain containing
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDNF neuron-derived neurotrophic factor
NPHP1 nephronophthisis 1 (juvenile)
NPTX1 neuronal pentraxin I
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSMR oncostatin M receptor
PALMD palmdelphin
PAQR5 progestin and adipoQ receptor family member V
PCDHA9 protocadherin alpha 9
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POPDC2 popeye domain containing 2
PQLC2 PQ loop repeat containing 2
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGCC regulator of cell cycle
RNF122 ring finger protein 122
RPGRIP1L RPGRIP1-like
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SLITRK5 SLIT and NTRK-like family, member 5
SMO smoothened, frizzled class receptor
SNTG1 syntrophin, gamma 1
SP4 Sp4 transcription factor
SPIDR scaffolding protein involved in DNA repair
STON1 stonin 1
TESPA1 thymocyte expressed, positive selection associated 1
TNS4 tensin 4
TRIM25 tripartite motif containing 25
WDR62 WD repeat domain 62
ZNF639 zinc finger protein 639
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76