meptazinol-7326 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the meptazinol-7326 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACSL4 acyl-CoA synthetase long-chain family member 4
ADRBK2 adrenergic, beta, receptor kinase 2
AHI1 Abelson helper integration site 1
AK1 adenylate kinase 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
AR androgen receptor
ARMC4 armadillo repeat containing 4
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATG3 autophagy related 3
C22ORF46 chromosome 22 open reading frame 46
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD82 CD82 molecule
CLCN5 chloride channel, voltage-sensitive 5
CYHR1 cysteine/histidine-rich 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK5 dedicator of cytokinesis 5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGFR epidermal growth factor receptor
ERCC2 excision repair cross-complementation group 2
ETV5 ets variant 5
FH fumarate hydratase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAMT guanidinoacetate N-methyltransferase
GLIPR1 GLI pathogenesis-related 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GOLGA2 golgin A2
GON4L gon-4-like (C. elegans)
GPR137 G protein-coupled receptor 137
GSPT1 G1 to S phase transition 1
HFE hemochromatosis
HOXA7 homeobox A7
HOXB9 homeobox B9
HOXC10 homeobox C10
HPS1 Hermansky-Pudlak syndrome 1
HR hair growth associated
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
KIF1A kinesin family member 1A
KPNA5 karyopherin alpha 5 (importin alpha 6)
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPK7 mitogen-activated protein kinase 7
MCAM melanoma cell adhesion molecule
MFAP3L microfibrillar-associated protein 3-like
MINK1 misshapen-like kinase 1
NIPAL2 NIPA-like domain containing 2
NKX3-2 NK3 homeobox 2
NME5 NME/NM23 family member 5
NXF2 nuclear RNA export factor 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE8B phosphodiesterase 8B
PICK1 protein interacting with PRKCA 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PITX2 paired-like homeodomain 2
PLCL2 phospholipase C-like 2
PLIN2 perilipin 2
PLK3 polo-like kinase 3
POFUT1 protein O-fucosyltransferase 1
POMT2 protein-O-mannosyltransferase 2
PTPRS protein tyrosine phosphatase, receptor type, S
PXN paxillin
RAB11B RAB11B, member RAS oncogene family
RGS2 regulator of G-protein signaling 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RSU1 Ras suppressor protein 1
SBF1 SET binding factor 1
SCAPER S-phase cyclin A-associated protein in the ER
SENP5 SUMO1/sentrin specific peptidase 5
SERHL2 serine hydrolase-like 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIK3 SIK family kinase 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMR3A submaxillary gland androgen regulated protein 3A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTA1 syntrophin, alpha 1
SORT1 sortilin 1
SOX13 SRY (sex determining region Y)-box 13
SOX3 SRY (sex determining region Y)-box 3
SSPN sarcospan
SYMPK symplekin
TIMP3 TIMP metallopeptidase inhibitor 3
TMOD1 tropomodulin 1
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRA2A transformer 2 alpha homolog (Drosophila)
TRIM29 tripartite motif containing 29
UBXN1 UBX domain protein 1
WDR1 WD repeat domain 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF219 zinc finger protein 219

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
BCL9 B-cell CLL/lymphoma 9
C11ORF30 chromosome 11 open reading frame 30
C19ORF40 chromosome 19 open reading frame 40
C9ORF91 chromosome 9 open reading frame 91
CBR1 carbonyl reductase 1
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCDC85C coiled-coil domain containing 85C
CDK9 cyclin-dependent kinase 9
CEP85 centrosomal protein 85kDa
CHML choroideremia-like (Rab escort protein 2)
CIC capicua transcriptional repressor
CIDEC cell death-inducing DFFA-like effector c
CLDN9 claudin 9
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CTNNBL1 catenin, beta like 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOCK1 dedicator of cytokinesis 1
ECHDC2 enoyl CoA hydratase domain containing 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA2 EPH receptor A2
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
FANCE Fanconi anemia, complementation group E
FBXL15 F-box and leucine-rich repeat protein 15
FBXO31 F-box protein 31
FGD6 FYVE, RhoGEF and PH domain containing 6
FRS2 fibroblast growth factor receptor substrate 2
GCHFR GTP cyclohydrolase I feedback regulator
GLS2 glutaminase 2 (liver, mitochondrial)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
H2AFY2 H2A histone family, member Y2
HDAC4 histone deacetylase 4
HIST1H2BC histone cluster 1, H2bc
HIST2H2AA3 histone cluster 2, H2aa3
HP1BP3 heterochromatin protein 1, binding protein 3
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
ICK intestinal cell (MAK-like) kinase
INCENP inner centromere protein antigens 135/155kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ITPKB inositol-trisphosphate 3-kinase B
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KREMEN2 kringle containing transmembrane protein 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC642236 FSHD region gene 1 pseudogene
LRRC49 leucine rich repeat containing 49
MAPKBP1 mitogen-activated protein kinase binding protein 1
MATK megakaryocyte-associated tyrosine kinase
MBIP MAP3K12 binding inhibitory protein 1
MNS1 meiosis-specific nuclear structural 1
MOSPD3 motile sperm domain containing 3
MRPL52 mitochondrial ribosomal protein L52
MTERF4 mitochondrial transcription termination factor 4
MXD3 MAX dimerization protein 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NRSN2 neurensin 2
OLFML3 olfactomedin-like 3
OSMR oncostatin M receptor
PDZRN3 PDZ domain containing ring finger 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPRU protein tyrosine phosphatase, receptor type, U
PYGB phosphorylase, glycogen; brain
RAB5C RAB5C, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RECQL4 RecQ protein-like 4
RFTN1 raftlin, lipid raft linker 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYTL2 synaptotagmin-like 2
TGFB3 transforming growth factor, beta 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TRIM5 tripartite motif containing 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
ULBP2 UL16 binding protein 2
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
WDR13 WD repeat domain 13
WDR60 WD repeat domain 60
ZNF205 zinc finger protein 205
ZNF428 zinc finger protein 428
ZNF480 zinc finger protein 480