meptazinol-4774 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the meptazinol-4774 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARHGAP44 Rho GTPase activating protein 44
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BTN2A2 butyrophilin, subfamily 2, member A2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CD46 CD46 molecule, complement regulatory protein
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEP162 centrosomal protein 162kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CGA glycoprotein hormones, alpha polypeptide
CLDND1 claudin domain containing 1
CLGN calmegin
COL1A1 collagen, type I, alpha 1
CRHR1 corticotropin releasing hormone receptor 1
DCAF13 DDB1 and CUL4 associated factor 13
DGKE diacylglycerol kinase, epsilon 64kDa
DOPEY2 dopey family member 2
ELP6 elongator acetyltransferase complex subunit 6
EPHB2 EPH receptor B2
ERCC2 excision repair cross-complementation group 2
ETAA1 Ewing tumor-associated antigen 1
FAM76A family with sequence similarity 76, member A
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FH fumarate hydratase
FRMPD1 FERM and PDZ domain containing 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GFI1 growth factor independent 1 transcription repressor
GPR1 G protein-coupled receptor 1
GSPT1 G1 to S phase transition 1
GUSBP3 glucuronidase, beta pseudogene 3
HBEGF heparin-binding EGF-like growth factor
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HOXC5 homeobox C5
HSPA12A heat shock 70kDa protein 12A
ICA1 islet cell autoantigen 1, 69kDa
IDI2-AS1 IDI2 antisense RNA 1
IGHA1 immunoglobulin heavy constant alpha 1
IGLL1 immunoglobulin lambda-like polypeptide 1
INHBE inhibin, beta E
ITGA6 integrin, alpha 6
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIDINS220 kinase D-interacting substrate, 220kDa
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL20 kelch-like family member 20
LDHAL6B lactate dehydrogenase A-like 6B
LDHB lactate dehydrogenase B
LRRN3 leucine rich repeat neuronal 3
LTC4S leukotriene C4 synthase
MARK4 MAP/microtubule affinity-regulating kinase 4
MCF2L MCF.2 cell line derived transforming sequence-like
MID1 midline 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MON2 MON2 homolog (S. cerevisiae)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NUDCD3 NudC domain containing 3
OLFML2A olfactomedin-like 2A
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PAPPA2 pappalysin 2
PEX11A peroxisomal biogenesis factor 11 alpha
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTBP3 polypyrimidine tract binding protein 3
PUM1 pumilio RNA-binding family member 1
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RANBP1 RAN binding protein 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
SAFB2 scaffold attachment factor B2
SBNO1 strawberry notch homolog 1 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SERGEF secretion regulating guanine nucleotide exchange factor
SFTPB surfactant protein B
SLA Src-like-adaptor
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC35F5 solute carrier family 35, member F5
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNN stannin
ST7 suppression of tumorigenicity 7
STK3 serine/threonine kinase 3
STX7 syntaxin 7
SYN3 synapsin III
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TBC1D19 TBC1 domain family, member 19
TDRD1 tudor domain containing 1
TENM4 teneurin transmembrane protein 4
VARS valyl-tRNA synthetase
VIPR1 vasoactive intestinal peptide receptor 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WNT5A wingless-type MMTV integration site family, member 5A
ZBED4 zinc finger, BED-type containing 4
ZNF141 zinc finger protein 141
ZNF44 zinc finger protein 44
ZNF440 zinc finger protein 440
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BATF basic leucine zipper transcription factor, ATF-like
C5ORF45 chromosome 5 open reading frame 45
CAPN15 calpain 15
CDC37 cell division cycle 37
CENPO centromere protein O
CIC capicua transcriptional repressor
CLDN4 claudin 4
CLIC3 chloride intracellular channel 3
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CORO1A coronin, actin binding protein, 1A
CTAGE9 CTAGE family, member 9
CUEDC1 CUE domain containing 1
DEAF1 DEAF1 transcription factor
DOC2A double C2-like domains, alpha
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DSCAM Down syndrome cell adhesion molecule
ECHDC2 enoyl CoA hydratase domain containing 2
EDC4 enhancer of mRNA decapping 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGLN2 egl-9 family hypoxia-inducible factor 2
FAM155B family with sequence similarity 155, member B
FKBP10 FK506 binding protein 10, 65 kDa
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GCHFR GTP cyclohydrolase I feedback regulator
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNL1 guanine nucleotide binding protein-like 1
GRB7 growth factor receptor-bound protein 7
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
H2AFY2 H2A histone family, member Y2
HIST1H1E histone cluster 1, H1e
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IQSEC2 IQ motif and Sec7 domain 2
IRF1 interferon regulatory factor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUNB jun B proto-oncogene
KLHL26 kelch-like family member 26
LAMA3 laminin, alpha 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRC61 leucine rich repeat containing 61
LYPLA2P1 lysophospholipase II pseudogene 1
MNX1 motor neuron and pancreas homeobox 1
MON1B MON1 secretory trafficking family member B
MPDU1 mannose-P-dolichol utilization defect 1
MVD mevalonate (diphospho) decarboxylase
MYO1E myosin IE
NRTN neurturin
NSD1 nuclear receptor binding SET domain protein 1
NTHL1 nth endonuclease III-like 1 (E. coli)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OTUD3 OTU deubiquitinase 3
PARD6A par-6 family cell polarity regulator alpha
PCBP4 poly(rC) binding protein 4
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPAN peter pan homolog (Drosophila)
PRKX protein kinase, X-linked
PRR14L proline rich 14-like
PTCD2 pentatricopeptide repeat domain 2
RHBDD3 rhomboid domain containing 3
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100A2 S100 calcium binding protein A2
S100A6 S100 calcium binding protein A6
SAMD9 sterile alpha motif domain containing 9
SDC3 syndecan 3
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SH2B3 SH2B adaptor protein 3
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SOX12 SRY (sex determining region Y)-box 12
STEAP4 STEAP family member 4
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TDRD12 tudor domain containing 12
THOP1 thimet oligopeptidase 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM51 transmembrane protein 51
TMEM53 transmembrane protein 53
TRIM25 tripartite motif containing 25
TSGA10 testis specific, 10
TTBK2 tau tubulin kinase 2
TTC26 tetratricopeptide repeat domain 26
UNC119 unc-119 homolog (C. elegans)
VGF VGF nerve growth factor inducible
WDR18 WD repeat domain 18
WRAP73 WD repeat containing, antisense to TP73
ZBED1 zinc finger, BED-type containing 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF134 zinc finger protein 134
ZNF34 zinc finger protein 34