mephentermine-4707 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the mephentermine-4707 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFAP1 actin filament associated protein 1
ALOX15 arachidonate 15-lipoxygenase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BHLHE40 basic helix-loop-helix family, member e40
BST2 bone marrow stromal cell antigen 2
BTG2 BTG family, member 2
C19ORF66 chromosome 19 open reading frame 66
C1ORF54 chromosome 1 open reading frame 54
CD47 CD47 molecule
CDK13 cyclin-dependent kinase 13
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL4A1 collagen, type IV, alpha 1
CRISP2 cysteine-rich secretory protein 2
CSF1 colony stimulating factor 1 (macrophage)
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DTNA dystrobrevin, alpha
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EN2 engrailed homeobox 2
FOXG1 forkhead box G1
GJA8 gap junction protein, alpha 8, 50kDa
GLRX3 glutaredoxin 3
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GSN gelsolin
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HFE hemochromatosis
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSF1 heat shock transcription factor 1
HSPG2 heparan sulfate proteoglycan 2
IFI27 interferon, alpha-inducible protein 27
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
LAMP3 lysosomal-associated membrane protein 3
LGALS2 lectin, galactoside-binding, soluble, 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOX lysyl oxidase
MAPK11 mitogen-activated protein kinase 11
MAPK8 mitogen-activated protein kinase 8
MCM3AP minichromosome maintenance complex component 3 associated protein
MRAS muscle RAS oncogene homolog
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MX2 MX dynamin-like GTPase 2
NCALD neurocalcin delta
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PARP12 poly (ADP-ribose) polymerase family, member 12
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLSCR1 phospholipid scramblase 1
PML promyelocytic leukemia
PNMAL1 paraneoplastic Ma antigen family-like 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PVR poliovirus receptor
QSER1 glutamine and serine rich 1
RAB40C RAB40C, member RAS oncogene family
RBBP9 retinoblastoma binding protein 9
RIN3 Ras and Rab interactor 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL35A ribosomal protein L35a
RRAGB Ras-related GTP binding B
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RUNX1 runt-related transcription factor 1
SCAND2P SCAN domain containing 2 pseudogene
SCRN3 secernin 3
SIM2 single-minded family bHLH transcription factor 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOCS6 suppressor of cytokine signaling 6
SP100 SP100 nuclear antigen
SP110 SP110 nuclear body protein
STAT1 signal transducer and activator of transcription 1, 91kDa
TDRKH tudor and KH domain containing
TGM2 transglutaminase 2
TOP3B topoisomerase (DNA) III beta
TRAK1 trafficking protein, kinesin binding 1
TRIM21 tripartite motif containing 21
YTHDC2 YTH domain containing 2
ZC3H13 zinc finger CCCH-type containing 13
ZNF204P zinc finger protein 204, pseudogene
ZNF24 zinc finger protein 24
ZNF609 zinc finger protein 609
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ACVR2B activin A receptor, type IIB
ALG12 ALG12, alpha-1,6-mannosyltransferase
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
ARC activity-regulated cytoskeleton-associated protein
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP13A2 ATPase type 13A2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D2 B9 protein domain 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
C22ORF29 chromosome 22 open reading frame 29
C22ORF46 chromosome 22 open reading frame 46
C2ORF27A chromosome 2 open reading frame 27A
C7ORF69 chromosome 7 open reading frame 69
CAPRIN2 caprin family member 2
CBX7 chromobox homolog 7
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD3D CD3d molecule, delta (CD3-TCR complex)
CD79A CD79a molecule, immunoglobulin-associated alpha
CLCN2 chloride channel, voltage-sensitive 2
CORT cortistatin
CRELD1 cysteine-rich with EGF-like domains 1
CTIF CBP80/20-dependent translation initiation factor
CUZD1 CUB and zona pellucida-like domains 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNALI1 dynein, axonemal, light intermediate chain 1
DYSF dysferlin
ELP6 elongator acetyltransferase complex subunit 6
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FAM46C family with sequence similarity 46, member C
FANCE Fanconi anemia, complementation group E
FLJ21369 uncharacterized protein FLJ21369
GLRA1 glycine receptor, alpha 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL1 guanine nucleotide binding protein-like 1
HCFC2 host cell factor C2
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
HYI hydroxypyruvate isomerase (putative)
IFT140 intraflagellar transport 140
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IRF6 interferon regulatory factor 6
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KLHL25 kelch-like family member 25
KLHL36 kelch-like family member 36
KREMEN2 kringle containing transmembrane protein 2
KRT31 keratin 31, type I
LIN7A lin-7 homolog A (C. elegans)
LMBR1L limb development membrane protein 1-like
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MGC12488
MNX1 motor neuron and pancreas homeobox 1
MTA2 metastasis associated 1 family, member 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PER3 period circadian clock 3
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLM polymerase (DNA directed), mu
PRB3 proline-rich protein BstNI subfamily 3
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS2 regulator of G-protein signaling 2
RIBC2 RIB43A domain with coiled-coils 2
RIN1 Ras and Rab interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
RPAP2 RNA polymerase II associated protein 2
RPUSD2 RNA pseudouridylate synthase domain containing 2
RUSC2 RUN and SH3 domain containing 2
SCGB2A2 secretoglobin, family 2A, member 2
SH2D4A SH2 domain containing 4A
SPAG4 sperm associated antigen 4
SPATA2L spermatogenesis associated 2-like
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX19 T-box 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMEM212 transmembrane protein 212
TMPRSS3 transmembrane protease, serine 3
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBB2B tubulin, beta 2B class IIb
UNC93B1 unc-93 homolog B1 (C. elegans)
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF35 zinc finger protein 35
ZNF510 zinc finger protein 510
ZNF696 zinc finger protein 696
ZNHIT2 zinc finger, HIT-type containing 2