mephenesin-4698 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the mephenesin-4698 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADGRG2 adhesion G protein-coupled receptor G2
AKR1C1 aldo-keto reductase family 1, member C1
AMPD1 adenosine monophosphate deaminase 1
ANGEL2 angel homolog 2 (Drosophila)
AOX1 aldehyde oxidase 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARNT aryl hydrocarbon receptor nuclear translocator
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLZF1 basic leucine zipper nuclear factor 1
BTF3P11 basic transcription factor 3 pseudogene 11
CALML5 calmodulin-like 5
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD300C CD300c molecule
CEND1 cell cycle exit and neuronal differentiation 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DMP1 dentin matrix acidic phosphoprotein 1
DMXL2 Dmx-like 2
DOK4 docking protein 4
DPF1 D4, zinc and double PHD fingers family 1
EDRF1 erythroid differentiation regulatory factor 1
EMP3 epithelial membrane protein 3
EN2 engrailed homeobox 2
FAS Fas cell surface death receptor
FH fumarate hydratase
FRMD1 FERM domain containing 1
GAS2L1 growth arrest-specific 2 like 1
GGT1 gamma-glutamyltransferase 1
GID4 GID complex subunit 4
GLRX3 glutaredoxin 3
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HBB hemoglobin, beta
HIST1H4A histone cluster 1, H4a
HYAL3 hyaluronoglucosaminidase 3
ICOSLG inducible T-cell co-stimulator ligand
IDUA iduronidase, alpha-L-
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMP1 lysosomal-associated membrane protein 1
LIG3 ligase III, DNA, ATP-dependent
LRP12 low density lipoprotein receptor-related protein 12
LTBP2 latent transforming growth factor beta binding protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPK7 mitogen-activated protein kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIA3 melanoma inhibitory activity family, member 3
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MST1 macrophage stimulating 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDRG2 NDRG family member 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NMT1 N-myristoyltransferase 1
NPC1 Niemann-Pick disease, type C1
OAZ3 ornithine decarboxylase antizyme 3
ORM1 orosomucoid 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PARVA parvin, alpha
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHA6 protocadherin alpha 6
PCNX pecanex homolog (Drosophila)
PDE8B phosphodiesterase 8B
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLAC1 placenta-specific 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PSD4 pleckstrin and Sec7 domain containing 4
PTHLH parathyroid hormone-like hormone
PTK2B protein tyrosine kinase 2 beta
QKI QKI, KH domain containing, RNA binding
RASAL2 RAS protein activator like 2
RECQL5 RecQ protein-like 5
RFXAP regulatory factor X-associated protein
RGS12 regulator of G-protein signaling 12
RNF122 ring finger protein 122
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPS3A ribosomal protein S3A
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCAND2P SCAN domain containing 2 pseudogene
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SIM2 single-minded family bHLH transcription factor 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SRCAP Snf2-related CREBBP activator protein
SRD5A3 steroid 5 alpha-reductase 3
TDRKH tudor and KH domain containing
TESC tescalcin
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
VTCN1 V-set domain containing T cell activation inhibitor 1
WNK1 WNK lysine deficient protein kinase 1
ZNF304 zinc finger protein 304
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAG4 BCL2-associated athanogene 4
BBC3 BCL2 binding component 3
C11ORF63 chromosome 11 open reading frame 63
C7ORF69 chromosome 7 open reading frame 69
CCDC130 coiled-coil domain containing 130
CCDC69 coiled-coil domain containing 69
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD79A CD79a molecule, immunoglobulin-associated alpha
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
CEL carboxyl ester lipase
CGREF1 cell growth regulator with EF-hand domain 1
CNGB3 cyclic nucleotide gated channel beta 3
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRYGC crystallin, gamma C
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DGAT1 diacylglycerol O-acyltransferase 1
DNALI1 dynein, axonemal, light intermediate chain 1
DSPP dentin sialophosphoprotein
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1L ERO1-like (S. cerevisiae)
FAM204A family with sequence similarity 204, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGF23 fibroblast growth factor 23
FLJ21369 uncharacterized protein FLJ21369
FLJ22184
GLRA1 glycine receptor, alpha 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
HCFC1 host cell factor C1
HCFC2 host cell factor C2
HIST1H2BN histone cluster 1, H2bn
HIST2H2AA3 histone cluster 2, H2aa3
HMOX1 heme oxygenase 1
HOXA4 homeobox A4
HOXC8 homeobox C8
HSPB6 heat shock protein, alpha-crystallin-related, B6
ITPKB inositol-trisphosphate 3-kinase B
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KLF13 Kruppel-like factor 13
KLHL28 kelch-like family member 28
KRT31 keratin 31, type I
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MUC3A mucin 3A, cell surface associated
NEUROD4 neuronal differentiation 4
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAT plasminogen activator, tissue
PMEL premelanosome protein
POLM polymerase (DNA directed), mu
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRB3 proline-rich protein BstNI subfamily 3
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTPRS protein tyrosine phosphatase, receptor type, S
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIN1 Ras and Rab interactor 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
S100A9 S100 calcium binding protein A9
SAMD9 sterile alpha motif domain containing 9
SCML2 sex comb on midleg-like 2 (Drosophila)
SLC12A9 solute carrier family 12, member 9
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNTA1 syntrophin, alpha 1
SP1 Sp1 transcription factor
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STMN3 stathmin-like 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTN2 tectonic family member 2
TEAD3 TEA domain family member 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRAIP TRAF interacting protein
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3D tubulin, alpha 3d
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF37BP zinc finger protein 37B, pseudogene
ZNF623 zinc finger protein 623