mephenesin-3675 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the mephenesin-3675 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADGRA2 adhesion G protein-coupled receptor A2
ALX4 ALX homeobox 4
ANXA10 annexin A10
ARMC4 armadillo repeat containing 4
ARSA arylsulfatase A
BMP2 bone morphogenetic protein 2
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCDC57 coiled-coil domain containing 57
CD5 CD5 molecule
CD82 CD82 molecule
CDK18 cyclin-dependent kinase 18
CNGB3 cyclic nucleotide gated channel beta 3
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CXXC4 CXXC finger protein 4
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DGCR2 DiGeorge syndrome critical region gene 2
DHRS12 dehydrogenase/reductase (SDR family) member 12
DIO2 deiodinase, iodothyronine, type II
DNAAF1 dynein, axonemal, assembly factor 1
FAM63A family with sequence similarity 63, member A
FAM65B family with sequence similarity 65, member B
FBXO21 F-box protein 21
FGFR4 fibroblast growth factor receptor 4
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPM6A glycoprotein M6A
GPR182 G protein-coupled receptor 182
HLA-DMB major histocompatibility complex, class II, DM beta
HOXB6 homeobox B6
HR hair growth associated
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGSF9B immunoglobulin superfamily, member 9B
IL1RN interleukin 1 receptor antagonist
INADL InaD-like (Drosophila)
INHBE inhibin, beta E
IRF4 interferon regulatory factor 4
IRS4 insulin receptor substrate 4
ITGA7 integrin, alpha 7
KERA keratocan
KIAA0319L KIAA0319-like
KLF13 Kruppel-like factor 13
KRIT1 KRIT1, ankyrin repeat containing
LAT2 linker for activation of T cells family, member 2
LPA lipoprotein, Lp(a)
LPAR4 lysophosphatidic acid receptor 4
LRRTM2 leucine rich repeat transmembrane neuronal 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MEGF6 multiple EGF-like-domains 6
MEOX1 mesenchyme homeobox 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MMP25 matrix metallopeptidase 25
MPPE1 metallophosphoesterase 1
MUC7 mucin 7, secreted
N4BP2L1 NEDD4 binding protein 2-like 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCLN nicalin
NME5 NME/NM23 family member 5
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTF3 neurotrophin 3
NTNG1 netrin G1
OGFR opioid growth factor receptor
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCP4 Purkinje cell protein 4
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE4B phosphodiesterase 4B, cAMP-specific
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PKNOX2 PBX/knotted 1 homeobox 2
PLA2R1 phospholipase A2 receptor 1, 180kDa
POU3F4 POU class 3 homeobox 4
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM14 PR domain containing 14
PRLR prolactin receptor
PSG4 pregnancy specific beta-1-glycoprotein 4
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBBP9 retinoblastoma binding protein 9
RIMS2 regulating synaptic membrane exocytosis 2
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RUNX1 runt-related transcription factor 1
SH2D3A SH2 domain containing 3A
SH3BP2 SH3-domain binding protein 2
SLAMF8 SLAM family member 8
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SOCS7 suppressor of cytokine signaling 7
STARD8 StAR-related lipid transfer (START) domain containing 8
TACSTD2 tumor-associated calcium signal transducer 2
TAGLN3 transgelin 3
TBL1Y transducin (beta)-like 1, Y-linked
TBX5 T-box 5
TLX2 T-cell leukemia homeobox 2
TOP3B topoisomerase (DNA) III beta
TPM3 tropomyosin 3
TUBA4B tubulin, alpha 4b
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WNT16 wingless-type MMTV integration site family, member 16
ZCCHC14 zinc finger, CCHC domain containing 14
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABHD8 abhydrolase domain containing 8
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AMT aminomethyltransferase
ARC activity-regulated cytoskeleton-associated protein
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C17ORF80 chromosome 17 open reading frame 80
C19ORF40 chromosome 19 open reading frame 40
C1R complement component 1, r subcomponent
C8ORF44 chromosome 8 open reading frame 44
CAMKMT calmodulin-lysine N-methyltransferase
CCDC71 coiled-coil domain containing 71
CCDC85C coiled-coil domain containing 85C
CDHR2 cadherin-related family member 2
CES3 carboxylesterase 3
CLDN11 claudin 11
CORO2A coronin, actin binding protein, 2A
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CXCL3 chemokine (C-X-C motif) ligand 3
CYB5R4 cytochrome b5 reductase 4
EIF5A2 eukaryotic translation initiation factor 5A2
ENO3 enolase 3 (beta, muscle)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERO1LB ERO1-like beta (S. cerevisiae)
EXOC6B exocyst complex component 6B
F3 coagulation factor III (thromboplastin, tissue factor)
FGL1 fibrinogen-like 1
FLJ21369 uncharacterized protein FLJ21369
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAN gigaxonin
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR19 G protein-coupled receptor 19
GRPR gastrin-releasing peptide receptor
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2BJ histone cluster 1, H2bj
HIST1H3G histone cluster 1, H3g
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFI6 interferon, alpha-inducible protein 6
IFT81 intraflagellar transport 81
INO80D INO80 complex subunit D
IQCC IQ motif containing C
KDM7A lysine (K)-specific demethylase 7A
KIFC3 kinesin family member C3
KRT8P12 keratin 8 pseudogene 12
LOC157562 uncharacterized LOC157562
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MMP3 matrix metallopeptidase 3
MTMR12 myotubularin related protein 12
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
NEK11 NIMA-related kinase 11
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NID2 nidogen 2 (osteonidogen)
NIPAL2 NIPA-like domain containing 2
NPHP1 nephronophthisis 1 (juvenile)
OSMR oncostatin M receptor
PDE12 phosphodiesterase 12
PER3 period circadian clock 3
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PODXL2 podocalyxin-like 2
PRR15L proline rich 15-like
PRR4 proline rich 4 (lacrimal)
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB33B RAB33B, member RAS oncogene family
RASL11B RAS-like, family 11, member B
RNASE4 ribonuclease, RNase A family, 4
RNF122 ring finger protein 122
RNFT1 ring finger protein, transmembrane 1
RPA4 replication protein A4, 30kDa
SCML2 sex comb on midleg-like 2 (Drosophila)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC46A3 solute carrier family 46, member 3
SMO smoothened, frizzled class receptor
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TFCP2L1 transcription factor CP2-like 1
TMEM180 transmembrane protein 180
TMEM212 transmembrane protein 212
TMSB15A thymosin beta 15a
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRABD TraB domain containing
TRIM25 tripartite motif containing 25
VN1R1 vomeronasal 1 receptor 1
ZC3H12A zinc finger CCCH-type containing 12A
ZFP69B ZFP69 zinc finger protein B
ZNF227 zinc finger protein 227
ZNF230 zinc finger protein 230
ZNF428 zinc finger protein 428
ZNF528 zinc finger protein 528
ZNF639 zinc finger protein 639
ZNF768 zinc finger protein 768
ZNF84 zinc finger protein 84