meiotic recombination initiation complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that initiates the formation of double-strand breaks (DSBs) required for meiotic recombination. Consists of a protein that catalyses formation of the double-strand breaks (Spo11 in S. cerevisiae and Rec12 in S. pombe), and a number of accessory proteins. (Gene Ontology, GO_0035808)
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13 proteins co-occuring with the meiotic recombination initiation complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SPO11 SPO11 meiotic protein covalently bound to DSB 1.63598
WDR61 WD repeat domain 61 1.48532
FKBP2 FK506 binding protein 2, 13kDa 0.847451
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.787817
SETD1A SET domain containing 1A 0.709251
TRIP13 thyroid hormone receptor interactor 13 0.705273
ATR ATR serine/threonine kinase 0.553905
EIF4E eukaryotic translation initiation factor 4E 0.418468
DBF4 DBF4 zinc finger 0.280716
CDC7 cell division cycle 7 0.20574
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.172735
H3F3A H3 histone, family 3A 0.170371
H3F3B H3 histone, family 3B (H3.3B) 0.170371