mefexamide-7478 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the mefexamide-7478 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AMH anti-Mullerian hormone
ANKRD26 ankyrin repeat domain 26
APOC1 apolipoprotein C-I
AQP3 aquaporin 3 (Gill blood group)
ARTN artemin
ATAD2B ATPase family, AAA domain containing 2B
BAIAP2 BAI1-associated protein 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
CAPG capping protein (actin filament), gelsolin-like
CEP104 centrosomal protein 104kDa
CLMN calmin (calponin-like, transmembrane)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRY2 cryptochrome circadian clock 2
CXCR4 chemokine (C-X-C motif) receptor 4
DALRD3 DALR anticodon binding domain containing 3
DGCR2 DiGeorge syndrome critical region gene 2
DPP4 dipeptidyl-peptidase 4
EPHA1 EPH receptor A1
FAM212B family with sequence similarity 212, member B
FBXL6 F-box and leucine-rich repeat protein 6
FGFR1 fibroblast growth factor receptor 1
FLJ11710 uncharacterized protein FLJ11710
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
HOMER3 homer scaffolding protein 3
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL9R interleukin 9 receptor
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0930 KIAA0930
KLF2 Kruppel-like factor 2
KLHL22 kelch-like family member 22
LIN7A lin-7 homolog A (C. elegans)
LMO2 LIM domain only 2 (rhombotin-like 1)
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAP4 microtubule-associated protein 4
MAPK12 mitogen-activated protein kinase 12
METTL7A methyltransferase like 7A
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MIER2 mesoderm induction early response 1, family member 2
MPZL1 myelin protein zero-like 1
MRPS14 mitochondrial ribosomal protein S14
NAAA N-acylethanolamine acid amidase
NF2 neurofibromin 2 (merlin)
NPIPB3 nuclear pore complex interacting protein family, member B3
PASK PAS domain containing serine/threonine kinase
PAX5 paired box 5
PCDHB3 protocadherin beta 3
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PEX1 peroxisomal biogenesis factor 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKNOX1 PBX/knotted 1 homeobox 1
PLK3 polo-like kinase 3
POLH polymerase (DNA directed), eta
PROL1 proline rich, lacrimal 1
RANBP1 RAN binding protein 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RECQL5 RecQ protein-like 5
RNFT2 ring finger protein, transmembrane 2
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SFTPB surfactant protein B
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SYNJ1 synaptojanin 1
TDRD3 tudor domain containing 3
TFEB transcription factor EB
THAP3 THAP domain containing, apoptosis associated protein 3
TMC7 transmembrane channel-like 7
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM2 transmembrane protein 2
TMEM57 transmembrane protein 57
TOR4A torsin family 4, member A
TSC22D3 TSC22 domain family, member 3
TTLL5 tubulin tyrosine ligase-like family member 5
TUBA4B tubulin, alpha 4b
UBE2L3 ubiquitin-conjugating enzyme E2L 3
VARS valyl-tRNA synthetase
VASH2 vasohibin 2
VIPR1 vasoactive intestinal peptide receptor 1
WDFY3 WD repeat and FYVE domain containing 3
ZBED1 zinc finger, BED-type containing 1
ZER1 zyg-11 related, cell cycle regulator
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF141 zinc finger protein 141
ZNF41 zinc finger protein 41
ZNF747 zinc finger protein 747
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ALOX15 arachidonate 15-lipoxygenase
APLP1 amyloid beta (A4) precursor-like protein 1
ATAD3A ATPase family, AAA domain containing 3A
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRAF B-Raf proto-oncogene, serine/threonine kinase
CAMK1 calcium/calmodulin-dependent protein kinase I
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD82 CD82 molecule
CDK3 cyclin-dependent kinase 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLCN5 chloride channel, voltage-sensitive 5
CLSPN claspin
CTSK cathepsin K
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK1 dedicator of cytokinesis 1
ELMO3 engulfment and cell motility 3
EPHA2 EPH receptor A2
FAM184A family with sequence similarity 184, member A
FAM86C1 family with sequence similarity 86, member C1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FMO4 flavin containing monooxygenase 4
FRS2 fibroblast growth factor receptor substrate 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GAN gigaxonin
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPR27 G protein-coupled receptor 27
GPX2 glutathione peroxidase 2
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H4D histone cluster 1, H4d
HIST1H4F histone cluster 1, H4f
HIST2H2AA3 histone cluster 2, H2aa3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HS1BP3 HCLS1 binding protein 3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFT122 intraflagellar transport 122
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCTD20 potassium channel tetramerization domain containing 20
KLHL28 kelch-like family member 28
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LGALS4 lectin, galactoside-binding, soluble, 4
LIMS2 LIM and senescent cell antigen-like domains 2
LMBR1L limb development membrane protein 1-like
LTBP2 latent transforming growth factor beta binding protein 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD3 MAX dimerization protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAIP2B poly(A) binding protein interacting protein 2B
PEX26 peroxisomal biogenesis factor 26
PLA2G10 phospholipase A2, group X
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLE polymerase (DNA directed), epsilon, catalytic subunit
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PVRL3 poliovirus receptor-related 3
RAB3A RAB3A, member RAS oncogene family
RANGRF RAN guanine nucleotide release factor
RPL23AP32 ribosomal protein L23a pseudogene 32
RWDD2A RWD domain containing 2A
SCHIP1 schwannomin interacting protein 1
SECISBP2 SECIS binding protein 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35F5 solute carrier family 35, member F5
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SREK1IP1 SREK1-interacting protein 1
STAG3 stromal antigen 3
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TDRD1 tudor domain containing 1
TESK2 testis-specific kinase 2
THRAP3 thyroid hormone receptor associated protein 3
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM104 transmembrane protein 104
TMEM209 transmembrane protein 209
TMPRSS4 transmembrane protease, serine 4
TMSB15A thymosin beta 15a
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRABD TraB domain containing
TSPYL2 TSPY-like 2
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
XAB2 XPA binding protein 2
ZBTB39 zinc finger and BTB domain containing 39
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF219 zinc finger protein 219
ZNF573 zinc finger protein 573
ZNF668 zinc finger protein 668
ZNF778 zinc finger protein 778
ZXDC ZXD family zinc finger C