mefenamic acid-1863 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the mefenamic acid-1863 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACAD10 acyl-CoA dehydrogenase family, member 10
ACOT11 acyl-CoA thioesterase 11
ACOX1 acyl-CoA oxidase 1, palmitoyl
AHR aryl hydrocarbon receptor
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOC1 apolipoprotein C-I
ASB13 ankyrin repeat and SOCS box containing 13
ATF6B activating transcription factor 6 beta
ATP13A2 ATPase type 13A2
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BHLHE41 basic helix-loop-helix family, member e41
BMP2 bone morphogenetic protein 2
C22ORF29 chromosome 22 open reading frame 29
CCS copper chaperone for superoxide dismutase
CDC42 cell division cycle 42
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDR2L cerebellar degeneration-related protein 2-like
CEP164 centrosomal protein 164kDa
CEP41 centrosomal protein 41kDa
CHKA choline kinase alpha
CLCN3 chloride channel, voltage-sensitive 3
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAL4 dynein, axonemal, light chain 4
DST dystonin
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EMD emerin
ERAP2 endoplasmic reticulum aminopeptidase 2
FAM3A family with sequence similarity 3, member A
FDPS farnesyl diphosphate synthase
GCAT glycine C-acetyltransferase
GPR20 G protein-coupled receptor 20
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HSPA4 heat shock 70kDa protein 4
ICK intestinal cell (MAK-like) kinase
ING1 inhibitor of growth family, member 1
INO80B INO80 complex subunit B
ISCA1 iron-sulfur cluster assembly 1
KAT2A K(lysine) acetyltransferase 2A
KRIT1 KRIT1, ankyrin repeat containing
L2HGDH L-2-hydroxyglutarate dehydrogenase
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MCM9 minichromosome maintenance complex component 9
MIIP migration and invasion inhibitory protein
MORC2 MORC family CW-type zinc finger 2
MRPL44 mitochondrial ribosomal protein L44
MYO1C myosin IC
OXLD1 oxidoreductase-like domain containing 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAQR3 progestin and adipoQ receptor family member III
PDLIM7 PDZ and LIM domain 7 (enigma)
PHACTR1 phosphatase and actin regulator 1
PQBP1 polyglutamine binding protein 1
PRDX2 peroxiredoxin 2
PRKCI protein kinase C, iota
PTTG3P pituitary tumor-transforming 3, pseudogene
QTRT1 queuine tRNA-ribosyltransferase 1
RAB33A RAB33A, member RAS oncogene family
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNFT1 ring finger protein, transmembrane 1
RPL13P5 ribosomal protein L13 pseudogene 5
RPS2 ribosomal protein S2
RWDD3 RWD domain containing 3
S100A11 S100 calcium binding protein A11
SBNO2 strawberry notch homolog 2 (Drosophila)
SCML1 sex comb on midleg-like 1 (Drosophila)
SLC16A4 solute carrier family 16, member 4
SLC25A44 solute carrier family 25, member 44
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOGA1 suppressor of glucose, autophagy associated 1
SOX15 SRY (sex determining region Y)-box 15
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STK11 serine/threonine kinase 11
SUGP1 SURP and G patch domain containing 1
TMEM2 transmembrane protein 2
TMEM70 transmembrane protein 70
TSC22D1 TSC22 domain family, member 1
TSC22D3 TSC22 domain family, member 3
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZC4H2 zinc finger, C4H2 domain containing
ZMYM2 zinc finger, MYM-type 2
ZNF609 zinc finger protein 609
ZNF665 zinc finger protein 665
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACPP acid phosphatase, prostate
APOLD1 apolipoprotein L domain containing 1
APOO apolipoprotein O
ARID5A AT rich interactive domain 5A (MRF1-like)
ARMC7 armadillo repeat containing 7
ATG4A autophagy related 4A, cysteine peptidase
BAHD1 bromo adjacent homology domain containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C16ORF59 chromosome 16 open reading frame 59
C22ORF46 chromosome 22 open reading frame 46
C5AR1 complement component 5a receptor 1
CCDC69 coiled-coil domain containing 69
CCL2 chemokine (C-C motif) ligand 2
CD320 CD320 molecule
CD82 CD82 molecule
CENPT centromere protein T
CHMP6 charged multivesicular body protein 6
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIDEC cell death-inducing DFFA-like effector c
COL15A1 collagen, type XV, alpha 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM184A family with sequence similarity 184, member A
FAM188A family with sequence similarity 188, member A
FAM204A family with sequence similarity 204, member A
FGGY FGGY carbohydrate kinase domain containing
FPGS folylpolyglutamate synthase
GSTM2 glutathione S-transferase mu 2 (muscle)
GTF2IRD1 GTF2I repeat domain containing 1
HIST1H2BI histone cluster 1, H2bi
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI30 interferon, gamma-inducible protein 30
IFI44L interferon-induced protein 44-like
IFT81 intraflagellar transport 81
IL24 interleukin 24
IL4R interleukin 4 receptor
IPO8 importin 8
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0319L KIAA0319-like
LIMD2 LIM domain containing 2
LPPR3 lipid phosphate phosphatase-related protein type 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LY6E lymphocyte antigen 6 complex, locus E
LY96 lymphocyte antigen 96
MATK megakaryocyte-associated tyrosine kinase
MDM4 MDM4, p53 regulator
METTL8 methyltransferase like 8
MOCS3 molybdenum cofactor synthesis 3
MPI mannose phosphate isomerase
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PEX13 peroxisomal biogenesis factor 13
PGM3 phosphoglucomutase 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PIAS3 protein inhibitor of activated STAT, 3
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLTP phospholipid transfer protein
PRKCZ protein kinase C, zeta
PTCD1 pentatricopeptide repeat domain 1
RABL6 RAB, member RAS oncogene family-like 6
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNF122 ring finger protein 122
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPP38 ribonuclease P/MRP 38kDa subunit
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S1PR4 sphingosine-1-phosphate receptor 4
SHPK sedoheptulokinase
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNHG20 small nucleolar RNA host gene 20
SPATA20 spermatogenesis associated 20
STX5 syntaxin 5
TAOK1 TAO kinase 1
TEC tec protein tyrosine kinase
TMEM110 transmembrane protein 110
TMEM242 transmembrane protein 242
TRAF1 TNF receptor-associated factor 1
TSPAN32 tetraspanin 32
TST thiosulfate sulfurtransferase (rhodanese)
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VSIG4 V-set and immunoglobulin domain containing 4
WT1-AS WT1 antisense RNA
XYLT2 xylosyltransferase II
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC18 zinc finger, DHHC-type containing 18
ZFYVE21 zinc finger, FYVE domain containing 21
ZMYM3 zinc finger, MYM-type 3
ZNF10 zinc finger protein 10
ZNF197 zinc finger protein 197
ZNF215 zinc finger protein 215
ZNF571 zinc finger protein 571
ZNF747 zinc finger protein 747
ZNF813 zinc finger protein 813