mefenamic acid-1821 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mefenamic acid-1821 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
AKAP13 A kinase (PRKA) anchor protein 13
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARHGAP10 Rho GTPase activating protein 10
ASF1A anti-silencing function 1A histone chaperone
ATG3 autophagy related 3
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BATF3 basic leucine zipper transcription factor, ATF-like 3
C17ORF85 chromosome 17 open reading frame 85
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC88C coiled-coil domain containing 88C
CCNA1 cyclin A1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEP68 centrosomal protein 68kDa
CHN2 chimerin 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLIC4 chloride intracellular channel 4
CNOT3 CCR4-NOT transcription complex, subunit 3
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DBT dihydrolipoamide branched chain transacylase E2
DEAF1 DEAF1 transcription factor
ELOVL6 ELOVL fatty acid elongase 6
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM188A family with sequence similarity 188, member A
FANCF Fanconi anemia, complementation group F
FCF1 FCF1 rRNA-processing protein
FGF1 fibroblast growth factor 1 (acidic)
FGF5 fibroblast growth factor 5
GAMT guanidinoacetate N-methyltransferase
GTSE1 G-2 and S-phase expressed 1
HAUS5 HAUS augmin-like complex, subunit 5
HSPA4 heat shock 70kDa protein 4
IL32 interleukin 32
JAK2 Janus kinase 2
JMJD6 jumonji domain containing 6
KDM7A lysine (K)-specific demethylase 7A
KRT33A keratin 33A, type I
KRT86 keratin 86, type II
LIME1 Lck interacting transmembrane adaptor 1
LMAN1 lectin, mannose-binding, 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD3 LY6/PLAUR domain containing 3
MAGEF1 melanoma antigen family F1
MAX MYC associated factor X
MED28 mediator complex subunit 28
MFSD6 major facilitator superfamily domain containing 6
MINK1 misshapen-like kinase 1
MLYCD malonyl-CoA decarboxylase
MTUS1 microtubule associated tumor suppressor 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOV nephroblastoma overexpressed
OSMR oncostatin M receptor
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PEX14 peroxisomal biogenesis factor 14
PGAP1 post-GPI attachment to proteins 1
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB27A RAB27A, member RAS oncogene family
RARS arginyl-tRNA synthetase
RDX radixin
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
SCAF4 SR-related CTD-associated factor 4
SCN1B sodium channel, voltage gated, type I beta subunit
SCYL3 SCY1-like 3 (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC39A9 solute carrier family 39, member 9
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SQLE squalene epoxidase
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STK17B serine/threonine kinase 17b
SUGP2 SURP and G patch domain containing 2
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TDRD3 tudor domain containing 3
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMPO thymopoietin
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF3IP2 TRAF3 interacting protein 2
TRIM2 tripartite motif containing 2
TRIOBP TRIO and F-actin binding protein
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TUBGCP3 tubulin, gamma complex associated protein 3
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VGLL3 vestigial-like family member 3
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZHX3 zinc fingers and homeoboxes 3

decreased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANAPC2 anaphase promoting complex subunit 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
BTBD2 BTB (POZ) domain containing 2
C1R complement component 1, r subcomponent
C8ORF60 chromosome 8 open reading frame 60
CA5BP1 carbonic anhydrase VB pseudogene 1
CALCOCO1 calcium binding and coiled-coil domain 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC130 coiled-coil domain containing 130
CCDC94 coiled-coil domain containing 94
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CINP cyclin-dependent kinase 2 interacting protein
CPEB1 cytoplasmic polyadenylation element binding protein 1
CSPP1 centrosome and spindle pole associated protein 1
CTSF cathepsin F
CXORF56 chromosome X open reading frame 56
DCLRE1A DNA cross-link repair 1A
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNMBP dynamin binding protein
DUSP8 dual specificity phosphatase 8
EIF5A2 eukaryotic translation initiation factor 5A2
EPHX2 epoxide hydrolase 2, cytoplasmic
EPPK1 epiplakin 1
FA2H fatty acid 2-hydroxylase
FANCE Fanconi anemia, complementation group E
GAL3ST4 galactose-3-O-sulfotransferase 4
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H3B histone cluster 1, H3b
HMHA1 histocompatibility (minor) HA-1
HOXC13 homeobox C13
HPS4 Hermansky-Pudlak syndrome 4
HSF2BP heat shock transcription factor 2 binding protein
IFI6 interferon, alpha-inducible protein 6
IFT22 intraflagellar transport 22
IL4R interleukin 4 receptor
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0894 KIAA0894 protein
KIFC3 kinesin family member C3
LAMC3 laminin, gamma 3
LIMS2 LIM and senescent cell antigen-like domains 2
LMNB1 lamin B1
LRP5L low density lipoprotein receptor-related protein 5-like
LZTR1 leucine-zipper-like transcription regulator 1
MAPK12 mitogen-activated protein kinase 12
MCMBP minichromosome maintenance complex binding protein
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MGC12488
MITF microphthalmia-associated transcription factor
NCS1 neuronal calcium sensor 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NT5DC3 5'-nucleotidase domain containing 3
NUBP2 nucleotide binding protein 2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
PARP3 poly (ADP-ribose) polymerase family, member 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RPGR retinitis pigmentosa GTPase regulator
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SAMD9 sterile alpha motif domain containing 9
SCML2 sex comb on midleg-like 2 (Drosophila)
SFT2D2 SFT2 domain containing 2
SHPK sedoheptulokinase
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMA4 glucuronidase, beta pseudogene
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPAG4 sperm associated antigen 4
SPATA2L spermatogenesis associated 2-like
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
TCTN2 tectonic family member 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUBG2 tubulin, gamma 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBTD1 ubiquitin domain containing 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF160 zinc finger protein 160
ZNF215 zinc finger protein 215
ZNF282 zinc finger protein 282
ZNF32 zinc finger protein 32
ZNF324 zinc finger protein 324
ZNF571 zinc finger protein 571
ZNF629 zinc finger protein 629
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene
ZNF862 zinc finger protein 862