mefenamic acid-1699 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the mefenamic acid-1699 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ALDOB aldolase B, fructose-bisphosphate
ARC activity-regulated cytoskeleton-associated protein
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARTN artemin
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASB1 ankyrin repeat and SOCS box containing 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF93 chromosome 14 open reading frame 93
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDC42 cell division cycle 42
CDK3 cyclin-dependent kinase 3
CFAP70 cilia and flagella associated protein 70
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COBLL1 cordon-bleu WH2 repeat protein-like 1
CPA4 carboxypeptidase A4
DRD2 dopamine receptor D2
DSC2 desmocollin 2
DVL3 dishevelled segment polarity protein 3
EFR3B EFR3 homolog B (S. cerevisiae)
EPS8L1 EPS8-like 1
FBXL7 F-box and leucine-rich repeat protein 7
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FLOT1 flotillin 1
FSCN1 fascin actin-bundling protein 1
GLRX glutaredoxin (thioltransferase)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPATCH4 G patch domain containing 4
HCRP1 hepatocellular carcinoma-related HCRP1
HEG1 heart development protein with EGF-like domains 1
HN1L hematological and neurological expressed 1-like
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNK1 potassium channel, two pore domain subfamily K, member 1
LRP5L low density lipoprotein receptor-related protein 5-like
MAP4 microtubule-associated protein 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL16 methyltransferase like 16
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MSI1 musashi RNA-binding protein 1
MXD4 MAX dimerization protein 4
NAIP NLR family, apoptosis inhibitory protein
NDE1 nudE neurodevelopment protein 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NLRX1 NLR family member X1
NOX1 NADPH oxidase 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PAIP2B poly(A) binding protein interacting protein 2B
PAOX polyamine oxidase (exo-N4-amino)
PCDHGA1 protocadherin gamma subfamily A, 1
PDCD6 programmed cell death 6
PICALM phosphatidylinositol binding clathrin assembly protein
PKNOX2 PBX/knotted 1 homeobox 2
PLCD1 phospholipase C, delta 1
PLK4 polo-like kinase 4
PMP22 peripheral myelin protein 22
POFUT1 protein O-fucosyltransferase 1
POU2F2 POU class 2 homeobox 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTRF polymerase I and transcript release factor
PVRL3 poliovirus receptor-related 3
RAD51B RAD51 paralog B
RNF126P1 ring finger protein 126 pseudogene 1
RPGR retinitis pigmentosa GTPase regulator
RPL7 ribosomal protein L7
SAFB scaffold attachment factor B
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLIT2 slit homolog 2 (Drosophila)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SRPR signal recognition particle receptor (docking protein)
SRRT serrate, RNA effector molecule
STC1 stanniocalcin 1
SUGP1 SURP and G patch domain containing 1
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
TADA2A transcriptional adaptor 2A
TMC6 transmembrane channel-like 6
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM184C transmembrane protein 184C
TMPRSS2 transmembrane protease, serine 2
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
WDFY3 WD repeat and FYVE domain containing 3
WDR25 WD repeat domain 25
WDR4 WD repeat domain 4
ZER1 zyg-11 related, cell cycle regulator
ZFPL1 zinc finger protein-like 1
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF224 zinc finger protein 224
ZNF304 zinc finger protein 304
ZNF324 zinc finger protein 324

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
ALS2CL ALS2 C-terminal like
ANKRD40 ankyrin repeat domain 40
ANXA2P3 annexin A2 pseudogene 3
ARHGAP11A Rho GTPase activating protein 11A
ARRB1 arrestin, beta 1
ATP13A2 ATPase type 13A2
C4ORF29 chromosome 4 open reading frame 29
CAPN15 calpain 15
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDK20 cyclin-dependent kinase 20
CHMP6 charged multivesicular body protein 6
CHPF chondroitin polymerizing factor
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIC capicua transcriptional repressor
CRABP1 cellular retinoic acid binding protein 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF10 DDB1 and CUL4 associated factor 10
DCLRE1A DNA cross-link repair 1A
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DENND4C DENN/MADD domain containing 4C
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGKD diacylglycerol kinase, delta 130kDa
DNM1 dynamin 1
EFNA3 ephrin-A3
EPHA2 EPH receptor A2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGD6 FYVE, RhoGEF and PH domain containing 6
FHOD1 formin homology 2 domain containing 1
FLT4 fms-related tyrosine kinase 4
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS2 glutaminase 2 (liver, mitochondrial)
GLTP glycolipid transfer protein
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GYS1 glycogen synthase 1 (muscle)
H2AFY2 H2A histone family, member Y2
HIRA histone cell cycle regulator
ICK intestinal cell (MAK-like) kinase
IDI2-AS1 IDI2 antisense RNA 1
IREB2 iron-responsive element binding protein 2
JUNB jun B proto-oncogene
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIFC1 kinesin family member C1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP9 microtubule-associated protein 9
MAST3 microtubule associated serine/threonine kinase 3
MFAP2 microfibrillar-associated protein 2
MFSD11 major facilitator superfamily domain containing 11
MID1IP1 MID1 interacting protein 1
MITF microphthalmia-associated transcription factor
MXD3 MAX dimerization protein 3
NFE2L3 nuclear factor, erythroid 2-like 3
NLK nemo-like kinase
NME6 NME/NM23 nucleoside diphosphate kinase 6
OLFML3 olfactomedin-like 3
PCBP4 poly(rC) binding protein 4
PDIA3 protein disulfide isomerase family A, member 3
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLXND1 plexin D1
PNPLA6 patatin-like phospholipase domain containing 6
PTPRE protein tyrosine phosphatase, receptor type, E
PYCRL pyrroline-5-carboxylate reductase-like
RAB4B RAB4B, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RNF216 ring finger protein 216
RPAP1 RNA polymerase II associated protein 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SH2D4A SH2 domain containing 4A
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPATA2L spermatogenesis associated 2-like
STK25 serine/threonine kinase 25
STX5 syntaxin 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TCTA T-cell leukemia translocation altered
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM183A transmembrane protein 183A
TMEM254 transmembrane protein 254
TNS2 tensin 2
TPTE transmembrane phosphatase with tensin homology
TRAF2 TNF receptor-associated factor 2
TRIM16 tripartite motif containing 16
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
UBE2O ubiquitin-conjugating enzyme E2O
ZFAND3 zinc finger, AN1-type domain 3
ZMAT5 zinc finger, matrin-type 5
ZNF430 zinc finger protein 430
ZNF652 zinc finger protein 652
ZNF696 zinc finger protein 696
ZNF710 zinc finger protein 710
ZNF778 zinc finger protein 778
ZNHIT2 zinc finger, HIT-type containing 2