medullary collecting duct Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Medullary collecting ducts are divided into outer and inner segments, the latter reaching more deeply into the medulla. The variable reabsorption of water and, depending on fluid balances and hormonal influences, the reabsorption or secretion of sodium, potassium, hydrogen and bicarbonate ion continues here. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004536)
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Genes

314 proteins co-occuring with the tissue medullary collecting duct in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
AQP2 aquaporin 2 (collecting duct) 2.98149
SLC14A2 solute carrier family 14 (urea transporter), member 2 2.1729
DNAH8 dynein, axonemal, heavy chain 8 2.02039
NPPA natriuretic peptide A 1.80158
RHBG Rh family, B glycoprotein (gene/pseudogene) 1.79144
RHCG Rh family, C glycoprotein 1.72385
AQP3 aquaporin 3 (Gill blood group) 1.71987
AVP arginine vasopressin 1.68105
AVPR2 arginine vasopressin receptor 2 1.44311
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.44033
ATP11A ATPase, class VI, type 11A 1.39376
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 1.3933
EDN1 endothelin 1 1.36769
AQP4 aquaporin 4 1.32958
SLC26A7 solute carrier family 26 (anion exchanger), member 7 1.31649
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 1.2931
CLCNKA chloride channel, voltage-sensitive Ka 1.27068
SCNN1B sodium channel, non voltage gated 1 beta subunit 1.26084
TALDO1 transaldolase 1 1.25726
CA2 carbonic anhydrase II 1.22069
LRRC47 leucine rich repeat containing 47 1.21846
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.2149
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 1.13324
EDNRA endothelin receptor type A 1.11907
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.10358
RHCE Rh blood group, CcEe antigens 1.09429
SLC26A4 solute carrier family 26 (anion exchanger), member 4 1.08192
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 1.07
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.05545
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.02513
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 1.02425
TTC26 tetratricopeptide repeat domain 26 1.02206
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 1.02162
RHD Rh blood group, D antigen 1.00283
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.999344
AQP1 aquaporin 1 (Colton blood group) 0.999344
KNG1 kininogen 1 0.99586
MPDZ multiple PDZ domain protein 0.969821
EDN3 endothelin 3 0.952116
REN renin 0.928906
SGK1 serum/glucocorticoid regulated kinase 1 0.925051
RGL3 ral guanine nucleotide dissociation stimulator-like 3 0.91308
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 0.9118
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.899871
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.899871
AQP6 aquaporin 6, kidney specific 0.876974
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.874439
STX7 syntaxin 7 0.860521
NPHP3 nephronophthisis 3 (adolescent) 0.859258
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.856732
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.854629
CYS1 cystin 1 0.852948
NSF N-ethylmaleimide-sensitive factor 0.850425
ADCY2 adenylate cyclase 2 (brain) 0.848325
SYT8 synaptotagmin VIII 0.839091
VAMP3 vesicle-associated membrane protein 3 0.838672
AGTRAP angiotensin II receptor-associated protein 0.821921
CA4 carbonic anhydrase IV 0.80271
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.795624
STX4 syntaxin 4 0.791044
CLCA4 chloride channel accessory 4 0.788131
MEGF9 multiple EGF-like-domains 9 0.776909
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.768197
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 0.767368
SORD sorbitol dehydrogenase 0.766954
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.764882
CLCA2 chloride channel accessory 2 0.756604
BICC1 BicC family RNA binding protein 1 0.741327
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 0.741327
NPPC natriuretic peptide C 0.739266
STXBP2 syntaxin binding protein 2 0.729797
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.721577
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.721166
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.719934
SNAPIN SNAP-associated protein 0.707221
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.700262
EDNRB endothelin receptor type B 0.696989
GUCY2C guanylate cyclase 2C 0.692493
NPR1 natriuretic peptide receptor 1 0.690042
WNK4 WNK lysine deficient protein kinase 4 0.686368
CLCA1 chloride channel accessory 1 0.672913
NEK8 NIMA-related kinase 8 0.671692
SAFB2 scaffold attachment factor B2 0.668029
MAPK9 mitogen-activated protein kinase 9 0.661929
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.658678
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.652994
SDCCAG8 serologically defined colon cancer antigen 8 0.64529
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 0.642858
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.640833
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.640428
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.639214
SLC4A3 solute carrier family 4 (anion exchanger), member 3 0.63719
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 0.635976
NEK9 NIMA-related kinase 9 0.635976
KLF12 Kruppel-like factor 12 0.634762
KCNK12 potassium channel, two pore domain subfamily K, member 12 0.632335
NPHP1 nephronophthisis 1 (juvenile) 0.631123
SUCNR1 succinate receptor 1 0.627081
ADM adrenomedullin 0.625869
PDE5A phosphodiesterase 5A, cGMP-specific 0.621831
KCNK13 potassium channel, two pore domain subfamily K, member 13 0.620217
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.619007
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.618603
NOS3 nitric oxide synthase 3 (endothelial cell) 0.61699
STC1 stanniocalcin 1 0.61578
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 0.615377
ECE1 endothelin converting enzyme 1 0.615377
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.61175
CEP290 centrosomal protein 290kDa 0.607319
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.601686
OXTR oxytocin receptor 0.600077
AKAP11 A kinase (PRKA) anchor protein 11 0.590437
RNASEH2A ribonuclease H2, subunit A 0.585625
CA12 carbonic anhydrase XII 0.580417
FXYD4 FXYD domain containing ion transport regulator 4 0.576816
MC3R melanocortin 3 receptor 0.572418
EGR1 early growth response 1 0.572018
PTH parathyroid hormone 0.56603
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 0.565232
CNTN1 contactin 1 0.56284
PALM paralemmin 0.559254
DNM1 dynamin 1 0.55408
CSNK1D casein kinase 1, delta 0.537416
PPARD peroxisome proliferator-activated receptor delta 0.537416
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.536229
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.535042
HSPA4L heat shock 70kDa protein 4-like 0.529508
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.524377
NPR3 natriuretic peptide receptor 3 0.51571
NOS1 nitric oxide synthase 1 (neuronal) 0.509813
DCPS decapping enzyme, scavenger 0.497657
HSPA4 heat shock 70kDa protein 4 0.495309
STX3 syntaxin 3 0.494136
CARS cysteinyl-tRNA synthetase 0.489447
BANF1 barrier to autointegration factor 1 0.489447
ZNF699 zinc finger protein 699 0.488667
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.485935
PRKCG protein kinase C, gamma 0.482428
ADRA2B adrenoceptor alpha 2B 0.480091
AQP12A aquaporin 12A 0.471927
WNK3 WNK lysine deficient protein kinase 3 0.470375
PTGES prostaglandin E synthase 0.468048
BMPR1A bone morphogenetic protein receptor, type IA 0.46766
PKP4 plakophilin 4 0.464174
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 0.4634
CHKA choline kinase alpha 0.462239
SLC26A9 solute carrier family 26 (anion exchanger), member 9 0.448731
PURB purine-rich element binding protein B 0.446038
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 0.444499
UMOD uromodulin 0.44181
DOT1L DOT1-like histone H3K79 methyltransferase 0.431077
TINAG tubulointerstitial nephritis antigen 0.429165
NCL nucleolin 0.426872
GRK4 G protein-coupled receptor kinase 4 0.42649
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.425726
DNM3 dynamin 3 0.423436
MET MET proto-oncogene, receptor tyrosine kinase 0.423054
MYO9B myosin IXB 0.422673
GPC3 glypican 3 0.417718
BMP7 bone morphogenetic protein 7 0.416195
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.413912
CLDN4 claudin 4 0.411251
NUP88 nucleoporin 88kDa 0.406694
IGF1 insulin-like growth factor 1 (somatomedin C) 0.404418
HOXB7 homeobox B7 0.401007
KIF3B kinesin family member 3B 0.399871
PNPLA6 patatin-like phospholipase domain containing 6 0.393819
FXYD2 FXYD domain containing ion transport regulator 2 0.391176
AQP7 aquaporin 7 0.387781
GLS glutaminase 0.38665
KL klotho 0.38552
CREB1 cAMP responsive element binding protein 1 0.385143
GCG glucagon 0.381379
MUT methylmalonyl CoA mutase 0.381003
PPARA peroxisome proliferator-activated receptor alpha 0.378372
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.374993
AKAP13 A kinase (PRKA) anchor protein 13 0.372369
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.37087
EPRS glutamyl-prolyl-tRNA synthetase 0.370121
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.369373
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 0.364139
GPC4 glypican 4 0.360409
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.356314
TGFB1 transforming growth factor, beta 1 0.345558
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 0.34371
NPTXR neuronal pentraxin receptor 0.34371
ATF2 activating transcription factor 2 0.341863
AQP11 aquaporin 11 0.337808
GLS2 glutaminase 2 (liver, mitochondrial) 0.335233
ADCY6 adenylate cyclase 6 0.332661
TPCN1 two pore segment channel 1 0.33156
EGFR epidermal growth factor receptor 0.328628
STX1A syntaxin 1A (brain) 0.322779
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.322414
FXYD1 FXYD domain containing ion transport regulator 1 0.32205
BDKRB2 bradykinin receptor B2 0.32132
RHAG Rh-associated glycoprotein 0.316951
DRD5 dopamine receptor D5 0.315498
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.315498
BSND barttin CLCNK-type chloride channel accessory beta subunit 0.312957
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.311507
CRYAB crystallin, alpha B 0.307889
GPR4 G protein-coupled receptor 4 0.306083
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.305001
PLS3 plastin 3 0.304279
PTPRA protein tyrosine phosphatase, receptor type, A 0.297447
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.296372
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.295297
FOXI1 forkhead box I1 0.294939
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.293151
NR1H2 nuclear receptor subfamily 1, group H, member 2 0.292793
HOXD3 homeobox D3 0.289582
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.289226
PKD2L1 polycystic kidney disease 2-like 1 0.276145
ADRA2A adrenoceptor alpha 2A 0.274744
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.270561
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.268828
ANXA2 annexin A2 0.259254
PPARG peroxisome proliferator-activated receptor gamma 0.258917
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.258243
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.256902
POLB polymerase (DNA directed), beta 0.254902
DDIT3 DNA-damage-inducible transcript 3 0.254902
ACTB actin, beta 0.250953
FXYD3 FXYD domain containing ion transport regulator 3 0.250627
INVS inversin 0.24804
NLE1 notchless homolog 1 (Drosophila) 0.246124
RPGRIP1L RPGRIP1-like 0.241132
MAPK10 mitogen-activated protein kinase 10 0.241132
ACTG1 actin gamma 1 0.23604
NT5C1A 5'-nucleotidase, cytosolic IA 0.233446
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.232039
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.23176
BORA bora, aurora kinase A activator 0.231482
JUN jun proto-oncogene 0.230931
CALB1 calbindin 1, 28kDa 0.229568
UTS2 urotensin 2 0.224893
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.223906
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.221521
OCRL oculocerebrorenal syndrome of Lowe 0.220831
GDF15 growth differentiation factor 15 0.220604
TPRG1L tumor protein p63 regulated 1-like 0.218613
NT5E 5'-nucleotidase, ecto (CD73) 0.218186
WT1 Wilms tumor 1 0.217974
OSGEP O-sialoglycoprotein endopeptidase 0.214576
MANF mesencephalic astrocyte-derived neurotrophic factor 0.212761
AQP5 aquaporin 5 0.212586
MAPK11 mitogen-activated protein kinase 11 0.212413
DEFB1 defensin, beta 1 0.194742
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.194112
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.193761
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.193706
CRNN cornulin 0.193628
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.193133
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.192279
XDH xanthine dehydrogenase 0.192122
ETV5 ets variant 5 0.191643
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.191342
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.190016
MLANA melan-A 0.188778
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.188751
WNT11 wingless-type MMTV integration site family, member 11 0.188002
KRT14 keratin 14, type I 0.187137
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.186635
GADD45A growth arrest and DNA-damage-inducible, alpha 0.186303
CALCRL calcitonin receptor-like 0.186235
KRT20 keratin 20, type I 0.186134
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.185307
ETV4 ets variant 4 0.184934
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.184896
RYR2 ryanodine receptor 2 (cardiac) 0.184768
KRT7 keratin 7, type II 0.183614
ADRA1D adrenoceptor alpha 1D 0.183372
ITGA1 integrin, alpha 1 0.182618
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.182388
RBSN rabenosyn, RAB effector 0.181202
TSC2 tuberous sclerosis 2 0.178351
PGD phosphogluconate dehydrogenase 0.177531
EPOR erythropoietin receptor 0.177285
CLCN3 chloride channel, voltage-sensitive 3 0.17652
MARK3 MAP/microtubule affinity-regulating kinase 3 0.175409
BSN bassoon presynaptic cytomatrix protein 0.175307
GSN gelsolin 0.174434
S100A6 S100 calcium binding protein A6 0.172867
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.170609
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.170508
CLDN3 claudin 3 0.169814
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.165213
SHB Src homology 2 domain containing adaptor protein B 0.165081
CTGF connective tissue growth factor 0.164137
EPHA1 EPH receptor A1 0.164045
PTPRF protein tyrosine phosphatase, receptor type, F 0.163538
MAPK14 mitogen-activated protein kinase 14 0.1633
APOPT1 apoptogenic 1, mitochondrial 0.163253
DNM2 dynamin 2 0.16268
BLVRA biliverdin reductase A 0.16219
ILK integrin-linked kinase 0.160511
RAB11A RAB11A, member RAS oncogene family 0.160511
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.160459
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.159445
CHD4 chromodomain helicase DNA binding protein 4 0.159391
RGMB repulsive guidance molecule family member b 0.158952
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.158952
EPHA5 EPH receptor A5 0.15884
SNAP25 synaptosomal-associated protein, 25kDa 0.158673
MMP10 matrix metallopeptidase 10 0.15845
CTTN cortactin 0.158284
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.157711
SMO smoothened, frizzled class receptor 0.156955
AKAP1 A kinase (PRKA) anchor protein 1 0.1566
S100A4 S100 calcium binding protein A4 0.156062
MC5R melanocortin 5 receptor 0.155757
CAV1 caveolin 1, caveolae protein, 22kDa 0.155573
RXFP1 relaxin/insulin-like family peptide receptor 1 0.155512