medrysone-3705 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the medrysone-3705 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE2 angiotensin I converting enzyme 2
ADAP1 ArfGAP with dual PH domains 1
ADGRD2 adhesion G protein-coupled receptor D2
ADRA1A adrenoceptor alpha 1A
ADRB3 adrenoceptor beta 3
ANGPTL4 angiopoietin-like 4
AQP4 aquaporin 4
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BMP2 bone morphogenetic protein 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C11ORF16 chromosome 11 open reading frame 16
C4BPA complement component 4 binding protein, alpha
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCR9 chemokine (C-C motif) receptor 9
CHAT choline O-acetyltransferase
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLDN18 claudin 18
CLEC1A C-type lectin domain family 1, member A
CLMN calmin (calponin-like, transmembrane)
CNTD2 cyclin N-terminal domain containing 2
DMBT1 deleted in malignant brain tumors 1
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
EIF3F eukaryotic translation initiation factor 3, subunit F
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ESR1 estrogen receptor 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXL18 F-box and leucine-rich repeat protein 18
FBXO4 F-box protein 4
FOXO4 forkhead box O4
FUT2 fucosyltransferase 2 (secretor status included)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG3 guanine nucleotide binding protein (G protein), gamma 3
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HCRTR2 hypocretin (orexin) receptor 2
HHAT hedgehog acyltransferase
HIST1H2AL histone cluster 1, H2al
ICAM5 intercellular adhesion molecule 5, telencephalin
IGL immunoglobulin lambda locus
IL12RB2 interleukin 12 receptor, beta 2
IL36G interleukin 36, gamma
INO80D INO80 complex subunit D
IPCEF1 interaction protein for cytohesin exchange factors 1
JADE2 jade family PHD finger 2
KIF21B kinesin family member 21B
KLK10 kallikrein-related peptidase 10
LTBP4 latent transforming growth factor beta binding protein 4
MEF2D myocyte enhancer factor 2D
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MORN1 MORN repeat containing 1
MTMR8 myotubularin related protein 8
NCALD neurocalcin delta
NMRK2 nicotinamide riboside kinase 2
NNMT nicotinamide N-methyltransferase
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NRF1 nuclear respiratory factor 1
NRP2 neuropilin 2
OPCML opioid binding protein/cell adhesion molecule-like
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OXCT2 3-oxoacid CoA transferase 2
PDLIM4 PDZ and LIM domain 4
PIP prolactin-induced protein
PLD1 phospholipase D1, phosphatidylcholine-specific
PLK3 polo-like kinase 3
PRB1 proline-rich protein BstNI subfamily 1
PRDM2 PR domain containing 2, with ZNF domain
PSD4 pleckstrin and Sec7 domain containing 4
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTCRA pre T-cell antigen receptor alpha
PTPRJ protein tyrosine phosphatase, receptor type, J
RAB40C RAB40C, member RAS oncogene family
RASL11B RAS-like, family 11, member B
REEP1 receptor accessory protein 1
RHAG Rh-associated glycoprotein
RIMS3 regulating synaptic membrane exocytosis 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SFTPB surfactant protein B
SH2D3C SH2 domain containing 3C
SKIL SKI-like proto-oncogene
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SOSTDC1 sclerostin domain containing 1
SOX2 SRY (sex determining region Y)-box 2
STAB2 stabilin 2
STRA6 stimulated by retinoic acid 6
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT11 synaptotagmin XI
TACC1 transforming, acidic coiled-coil containing protein 1
TAOK2 TAO kinase 2
TBCD tubulin folding cofactor D
TMPRSS6 transmembrane protease, serine 6
TTC12 tetratricopeptide repeat domain 12
WNT3 wingless-type MMTV integration site family, member 3
ZIC3 Zic family member 3
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADGRB2 adhesion G protein-coupled receptor B2
AGO4 argonaute RISC catalytic component 4
AK5 adenylate kinase 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2P1 annexin A2 pseudogene 1
APH1B APH1B gamma secretase subunit
ARSB arylsulfatase B
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BFSP1 beaded filament structural protein 1, filensin
BRIP1 BRCA1 interacting protein C-terminal helicase 1
CAMKMT calmodulin-lysine N-methyltransferase
CDH19 cadherin 19, type 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRDL1 chordin-like 1
CLDN14 claudin 14
CLSTN3 calsyntenin 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPED1 cadherin-like and PC-esterase domain containing 1
CXCL6 chemokine (C-X-C motif) ligand 6
CYBRD1 cytochrome b reductase 1
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DENND4A DENN/MADD domain containing 4A
ESM1 endothelial cell-specific molecule 1
EXOC5 exocyst complex component 5
GALK1 galactokinase 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDAC9 histone deacetylase 9
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSF2 heat shock transcription factor 2
IFI6 interferon, alpha-inducible protein 6
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KCTD17 potassium channel tetramerization domain containing 17
KIAA0513 KIAA0513
KIAA1107 KIAA1107
KIAA1549L KIAA1549-like
KLF3 Kruppel-like factor 3 (basic)
KRT34 keratin 34, type I
LIG4 ligase IV, DNA, ATP-dependent
LINC00341 long intergenic non-protein coding RNA 341
LPAR6 lysophosphatidic acid receptor 6
LY96 lymphocyte antigen 96
MAP3K7CL MAP3K7 C-terminal like
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN3 mucolipin 3
MEX3C mex-3 RNA binding family member C
MX1 MX dynamin-like GTPase 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTSR1 neurotensin receptor 1 (high affinity)
OCLN occludin
OGDHL oxoglutarate dehydrogenase-like
OSMR oncostatin M receptor
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PAN2 PAN2 poly(A) specific ribonuclease subunit
PEX13 peroxisomal biogenesis factor 13
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLAU plasminogen activator, urokinase
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
QSER1 glutamine and serine rich 1
RAB3A RAB3A, member RAS oncogene family
RGS19 regulator of G-protein signaling 19
RRAGB Ras-related GTP binding B
RUSC2 RUN and SH3 domain containing 2
RWDD2A RWD domain containing 2A
S100A3 S100 calcium binding protein A3
SAMD9 sterile alpha motif domain containing 9
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDC3 syndecan 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SGK2 serum/glucocorticoid regulated kinase 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SPIDR scaffolding protein involved in DNA repair
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAGLN3 transgelin 3
TBC1D17 TBC1 domain family, member 17
TMEM2 transmembrane protein 2
TMEM209 transmembrane protein 209
TMEM40 transmembrane protein 40
TMEM53 transmembrane protein 53
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBQLN4 ubiquilin 4
UGT8 UDP glycosyltransferase 8
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZNF180 zinc finger protein 180
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF675 zinc finger protein 675
ZNF702P zinc finger protein 702, pseudogene
ZNF747 zinc finger protein 747
ZW10 zw10 kinetochore protein