medrysone-2544 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the medrysone-2544 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABI2 abl-interactor 2
ACSF2 acyl-CoA synthetase family member 2
AGXT alanine-glyoxylate aminotransferase
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ANTXR1 anthrax toxin receptor 1
APOC4 apolipoprotein C-IV
AQP9 aquaporin 9
ATXN3 ataxin 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BMP10 bone morphogenetic protein 10
C11ORF80 chromosome 11 open reading frame 80
C6ORF10 chromosome 6 open reading frame 10
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CASS4 Cas scaffolding protein family member 4
CCKAR cholecystokinin A receptor
CCL20 chemokine (C-C motif) ligand 20
CD163 CD163 molecule
CD52 CD52 molecule
CD6 CD6 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CELA2A chymotrypsin-like elastase family, member 2A
COL14A1 collagen, type XIV, alpha 1
CSHL1 chorionic somatomammotropin hormone-like 1
DCLK2 doublecortin-like kinase 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFS embryonal Fyn-associated substrate
EPN3 epsin 3
FABP7 fatty acid binding protein 7, brain
FBXL2 F-box and leucine-rich repeat protein 2
FGFR2 fibroblast growth factor receptor 2
FLJ11292
FLJ13224 uncharacterized LOC79857
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLI2 GLI family zinc finger 2
GMPR guanosine monophosphate reductase
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HAO2 hydroxyacid oxidase 2 (long chain)
HIST1H2BN histone cluster 1, H2bn
IDS iduronate 2-sulfatase
IFITM1 interferon induced transmembrane protein 1
IGHM immunoglobulin heavy constant mu
IL1RN interleukin 1 receptor antagonist
IRX4 iroquois homeobox 4
KANK3 KN motif and ankyrin repeat domains 3
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KRTAP1-3 keratin associated protein 1-3
KSR1 kinase suppressor of ras 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LOC440895 two pore channel 3 pseudogene
LOX lysyl oxidase
MAL mal, T-cell differentiation protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTMR8 myotubularin related protein 8
NAG18 NAG18 mRNA
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NRG1 neuregulin 1
ODAM odontogenic, ameloblast asssociated
PALLD palladin, cytoskeletal associated protein
PAX3 paired box 3
PAX8 paired box 8
PER1 period circadian clock 1
PIP prolactin-induced protein
PKD2L2 polycystic kidney disease 2-like 2
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
PRMT8 protein arginine methyltransferase 8
PSG9 pregnancy specific beta-1-glycoprotein 9
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAPSN receptor-associated protein of the synapse
RGS4 regulator of G-protein signaling 4
RHOH ras homolog family member H
SCGB2A1 secretoglobin, family 2A, member 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSX1 synovial sarcoma, X breakpoint 1
SUGCT succinyl-CoA:glutarate-CoA transferase
TAAR5 trace amine associated receptor 5
TAGLN3 transgelin 3
TEKT2 tektin 2 (testicular)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THRA thyroid hormone receptor, alpha
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRAPPC9 trafficking protein particle complex 9
TRBC1 T cell receptor beta constant 1
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TUSC3 tumor suppressor candidate 3
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ATAD5 ATPase family, AAA domain containing 5
BBS1 Bardet-Biedl syndrome 1
BIK BCL2-interacting killer (apoptosis-inducing)
BRIX1 BRX1, biogenesis of ribosomes
C11ORF21 chromosome 11 open reading frame 21
C11ORF95 chromosome 11 open reading frame 95
C12ORF4 chromosome 12 open reading frame 4
C1GALT1C1 C1GALT1-specific chaperone 1
C4ORF29 chromosome 4 open reading frame 29
CCDC47 coiled-coil domain containing 47
CCNB1 cyclin B1
CEP83 centrosomal protein 83kDa
CHST10 carbohydrate sulfotransferase 10
COA3 cytochrome c oxidase assembly factor 3
COMMD8 COMM domain containing 8
CREB3 cAMP responsive element binding protein 3
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
ELP3 elongator acetyltransferase complex subunit 3
FAM86B1 family with sequence similarity 86, member B1
FBXO3 F-box protein 3
FICD FIC domain containing
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GDE1 glycerophosphodiester phosphodiesterase 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPALPP1 GPALPP motifs containing 1
GPHN gephyrin
GPS2 G protein pathway suppressor 2
GTF2I general transcription factor IIi
HRSP12 heat-responsive protein 12
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IRAK4 interleukin-1 receptor-associated kinase 4
KATNBL1 katanin p80 subunit B-like 1
KIAA0922 KIAA0922
KPNA4 karyopherin alpha 4 (importin alpha 3)
LINC00339 long intergenic non-protein coding RNA 339
LRRC42 leucine rich repeat containing 42
LTB lymphotoxin beta (TNF superfamily, member 3)
MCRS1 microspherule protein 1
MECR mitochondrial trans-2-enoyl-CoA reductase
METTL8 methyltransferase like 8
MNS1 meiosis-specific nuclear structural 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUM1 melanoma associated antigen (mutated) 1
NCSTN nicastrin
NHEJ1 nonhomologous end-joining factor 1
NOD1 nucleotide-binding oligomerization domain containing 1
PHYH phytanoyl-CoA 2-hydroxylase
PLA2G12A phospholipase A2, group XIIA
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDM13 PR domain containing 13
PRMT1 protein arginine methyltransferase 1
PSAT1 phosphoserine aminotransferase 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
QTRT1 queuine tRNA-ribosyltransferase 1
RANGAP1 Ran GTPase activating protein 1
RINT1 RAD50 interactor 1
RPGR retinitis pigmentosa GTPase regulator
RPL23AP7 ribosomal protein L23a pseudogene 7
SDAD1 SDA1 domain containing 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SKA1 spindle and kinetochore associated complex subunit 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A4RG SLC2A4 regulator
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SNIP1 Smad nuclear interacting protein 1
SNX5 sorting nexin 5
SOAT1 sterol O-acyltransferase 1
SOBP sine oculis binding protein homolog (Drosophila)
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SSFA2 sperm specific antigen 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK16 serine/threonine kinase 16
STK25 serine/threonine kinase 25
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TIGAR TP53 induced glycolysis regulatory phosphatase
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM16 tripartite motif containing 16
TRIM68 tripartite motif containing 68
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TUBGCP5 tubulin, gamma complex associated protein 5
TULP4 tubby like protein 4
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
WDR18 WD repeat domain 18
XPA xeroderma pigmentosum, complementation group A
ZBTB39 zinc finger and BTB domain containing 39
ZNF189 zinc finger protein 189
ZNF253 zinc finger protein 253
ZNF426 zinc finger protein 426