meclofenoxate-3405 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the meclofenoxate-3405 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGFG2 ArfGAP with FG repeats 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARID1A AT rich interactive domain 1A (SWI-like)
B9D1 B9 protein domain 1
BMP1 bone morphogenetic protein 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C17ORF59 chromosome 17 open reading frame 59
C9ORF9 chromosome 9 open reading frame 9
CACYBP calcyclin binding protein
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
COL6A1 collagen, type VI, alpha 1
COL9A3 collagen, type IX, alpha 3
CRYGC crystallin, gamma C
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYHR1 cysteine/histidine-rich 1
DCAF8 DDB1 and CUL4 associated factor 8
DGCR8 DGCR8 microprocessor complex subunit
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
EFNB3 ephrin-B3
EPHA1 EPH receptor A1
FBXO9 F-box protein 9
FH fumarate hydratase
FKBP8 FK506 binding protein 8, 38kDa
FPGT fucose-1-phosphate guanylyltransferase
FSCN1 fascin actin-bundling protein 1
GJA9 gap junction protein, alpha 9, 59kDa
GPATCH2L G patch domain containing 2-like
GPER1 G protein-coupled estrogen receptor 1
GRB7 growth factor receptor-bound protein 7
GSDMB gasdermin B
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
ICA1 islet cell autoantigen 1, 69kDa
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDS iduronate 2-sulfatase
IQCE IQ motif containing E
IRF8 interferon regulatory factor 8
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIAA0040 KIAA0040
KIAA0485 uncharacterized LOC57235
KLHL25 kelch-like family member 25
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LRRC14 leucine rich repeat containing 14
MARCKS myristoylated alanine-rich protein kinase C substrate
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MKL1 megakaryoblastic leukemia (translocation) 1
MUC3B mucin 3B, cell surface associated
MYB v-myb avian myeloblastosis viral oncogene homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX3-2 NK3 homeobox 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
OLFML2A olfactomedin-like 2A
ORAI2 ORAI calcium release-activated calcium modulator 2
OSBPL10 oxysterol binding protein-like 10
PACS1 phosphofurin acidic cluster sorting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMEL premelanosome protein
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLL polymerase (DNA directed), lambda
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PVT1 Pvt1 oncogene (non-protein coding)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RASAL2 RAS protein activator like 2
REEP1 receptor accessory protein 1
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
SAPCD1 suppressor APC domain containing 1
SH3BP2 SH3-domain binding protein 2
SOS2 son of sevenless homolog 2 (Drosophila)
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SURF1 surfeit 1
TBC1D17 TBC1 domain family, member 17
TBC1D22A TBC1 domain family, member 22A
TCF3 transcription factor 3
TDRD3 tudor domain containing 3
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM254 transmembrane protein 254
TONSL tonsoku-like, DNA repair protein
TTLL3 tubulin tyrosine ligase-like family member 3
UBOX5 U-box domain containing 5
UCN urocortin
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
UTRN utrophin
VGF VGF nerve growth factor inducible
WDR55 WD repeat domain 55
ZCCHC24 zinc finger, CCHC domain containing 24
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF277 zinc finger protein 277
ZNF500 zinc finger protein 500
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKRD40 ankyrin repeat domain 40
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARRB1 arrestin, beta 1
ATAD5 ATPase family, AAA domain containing 5
ATF7IP2 activating transcription factor 7 interacting protein 2
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AXIN1 axin 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BATF basic leucine zipper transcription factor, ATF-like
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BFSP1 beaded filament structural protein 1, filensin
C11ORF68 chromosome 11 open reading frame 68
C22ORF29 chromosome 22 open reading frame 29
C2ORF44 chromosome 2 open reading frame 44
CHML choroideremia-like (Rab escort protein 2)
CLK1 CDC-like kinase 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDHD2 DDHD domain containing 2
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
F3 coagulation factor III (thromboplastin, tissue factor)
FBXL2 F-box and leucine-rich repeat protein 2
FSD1 fibronectin type III and SPRY domain containing 1
GDAP1 ganglioside induced differentiation associated protein 1
GID4 GID complex subunit 4
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HIRA histone cell cycle regulator
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
LINC00339 long intergenic non-protein coding RNA 339
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP5L low density lipoprotein receptor-related protein 5-like
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MGC12488
MON1B MON1 secretory trafficking family member B
MSL2 male-specific lethal 2 homolog (Drosophila)
MTHFSD methenyltetrahydrofolate synthetase domain containing
NFE2L3 nuclear factor, erythroid 2-like 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
ODF2 outer dense fiber of sperm tails 2
ORAI3 ORAI calcium release-activated calcium modulator 3
PAQR6 progestin and adipoQ receptor family member VI
PARP12 poly (ADP-ribose) polymerase family, member 12
PES1 pescadillo ribosomal biogenesis factor 1
PGP phosphoglycolate phosphatase
PIBF1 progesterone immunomodulatory binding factor 1
PPT2 palmitoyl-protein thioesterase 2
PTPRU protein tyrosine phosphatase, receptor type, U
RAB23 RAB23, member RAS oncogene family
RRAGB Ras-related GTP binding B
SAYSD1 SAYSVFN motif domain containing 1
SH2B3 SH2B adaptor protein 3
SHARPIN SHANK-associated RH domain interactor
SIK1 salt-inducible kinase 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC46A3 solute carrier family 46, member 3
SPATA2L spermatogenesis associated 2-like
SPIDR scaffolding protein involved in DNA repair
SRD5A3 steroid 5 alpha-reductase 3
STAG3 stromal antigen 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCTN2 tectonic family member 2
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM132A transmembrane protein 132A
TMEM159 transmembrane protein 159
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRAIP TRAF interacting protein
TTBK2 tau tubulin kinase 2
TTC30A tetratricopeptide repeat domain 30A
TWF2 twinfilin actin binding protein 2
TXLNG taxilin gamma
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UNKL unkempt family zinc finger-like
VAX2 ventral anterior homeobox 2
XYLT2 xylosyltransferase II
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB3 zinc finger and BTB domain containing 3
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF134 zinc finger protein 134
ZNF432 zinc finger protein 432
ZNF652 zinc finger protein 652
ZSCAN26 zinc finger and SCAN domain containing 26