meclofenamic acid-7280 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the meclofenamic acid-7280 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ADGRL3 adhesion G protein-coupled receptor L3
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRWD1 bromodomain and WD repeat domain containing 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C9ORF156 chromosome 9 open reading frame 156
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CAV2 caveolin 2
CLCA1 chloride channel accessory 1
CLEC16A C-type lectin domain family 16, member A
COL7A1 collagen, type VII, alpha 1
CSF1R colony stimulating factor 1 receptor
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DAGLA diacylglycerol lipase, alpha
DHRS12 dehydrogenase/reductase (SDR family) member 12
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DST dystonin
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
ERCC1 excision repair cross-complementation group 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FGF2 fibroblast growth factor 2 (basic)
FLT1 fms-related tyrosine kinase 1
FXR2 fragile X mental retardation, autosomal homolog 2
GAS7 growth arrest-specific 7
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPER1 G protein-coupled estrogen receptor 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
IFI6 interferon, alpha-inducible protein 6
IRF1 interferon regulatory factor 1
KIF5C kinesin family member 5C
KLF3 Kruppel-like factor 3 (basic)
KRIT1 KRIT1, ankyrin repeat containing
KRT6B keratin 6B, type II
LHX2 LIM homeobox 2
LRP1 low density lipoprotein receptor-related protein 1
LRP12 low density lipoprotein receptor-related protein 12
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPK7 mitogen-activated protein kinase 7
MBD3 methyl-CpG binding domain protein 3
MBTD1 mbt domain containing 1
MED16 mediator complex subunit 16
MMP3 matrix metallopeptidase 3
MTAP methylthioadenosine phosphorylase
MXD4 MAX dimerization protein 4
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFX1 nuclear transcription factor, X-box binding 1
NKIRAS2 NFKB inhibitor interacting Ras-like 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSBPL10 oxysterol binding protein-like 10
PDLIM4 PDZ and LIM domain 4
PLEKHO1 pleckstrin homology domain containing, family O member 1
PTPRF protein tyrosine phosphatase, receptor type, F
RAB28 RAB28, member RAS oncogene family
RARG retinoic acid receptor, gamma
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RFK riboflavin kinase
RGS5 regulator of G-protein signaling 5
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROGDI rogdi homolog (Drosophila)
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUSC2 RUN and SH3 domain containing 2
S100A11 S100 calcium binding protein A11
S100A14 S100 calcium binding protein A14
SCAF4 SR-related CTD-associated factor 4
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SFTPB surfactant protein B
SH3BP2 SH3-domain binding protein 2
SIRT6 sirtuin 6
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC46A3 solute carrier family 46, member 3
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SOX2 SRY (sex determining region Y)-box 2
SPIDR scaffolding protein involved in DNA repair
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SYT17 synaptotagmin XVII
TLE4 transducin-like enhancer of split 4
TMC7 transmembrane channel-like 7
TMEM63A transmembrane protein 63A
TMEM8B transmembrane protein 8B
TRIM23 tripartite motif containing 23
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
TUBGCP2 tubulin, gamma complex associated protein 2
TYRO3 TYRO3 protein tyrosine kinase
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WNT7A wingless-type MMTV integration site family, member 7A
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZFP30 ZFP30 zinc finger protein
ZNF84 zinc finger protein 84

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
BCL9 B-cell CLL/lymphoma 9
BCORL1 BCL6 corepressor-like 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF112 chromosome 1 open reading frame 112
C7ORF43 chromosome 7 open reading frame 43
CALCOCO1 calcium binding and coiled-coil domain 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC25 coiled-coil domain containing 25
CCNO cyclin O
CDC37L1 cell division cycle 37-like 1
CDC45 cell division cycle 45
CDK9 cyclin-dependent kinase 9
CLDN14 claudin 14
CLDN15 claudin 15
CNGB3 cyclic nucleotide gated channel beta 3
CNN2 calponin 2
COCH cochlin
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUL9 cullin 9
DDN dendrin
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DYSF dysferlin
EPHA4 EPH receptor A4
FAM50B family with sequence similarity 50, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPATCH3 G patch domain containing 3
GSTM1 glutathione S-transferase mu 1
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H2AI histone cluster 1, H2ai
HOOK2 hook microtubule-tethering protein 2
HOXA4 homeobox A4
HOXC4 homeobox C4
HPS6 Hermansky-Pudlak syndrome 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IMPAD1 inositol monophosphatase domain containing 1
KIAA0895 KIAA0895
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPAR3 lysophosphatidic acid receptor 3
LPAR4 lysophosphatidic acid receptor 4
MANBA mannosidase, beta A, lysosomal
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MON1B MON1 secretory trafficking family member B
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MXRA8 matrix-remodelling associated 8
MYL5 myosin, light chain 5, regulatory
NAG18 NAG18 mRNA
NCS1 neuronal calcium sensor 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NPR3 natriuretic peptide receptor 3
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PACS1 phosphofurin acidic cluster sorting protein 1
PAQR4 progestin and adipoQ receptor family member IV
PARD6A par-6 family cell polarity regulator alpha
PCSK7 proprotein convertase subtilisin/kexin type 7
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PROSER1 proline and serine rich 1
PRR14L proline rich 14-like
PSKH1 protein serine kinase H1
PTCD2 pentatricopeptide repeat domain 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM42 RNA binding motif protein 42
RGS20 regulator of G-protein signaling 20
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF146 ring finger protein 146
RNF25 ring finger protein 25
RNF31 ring finger protein 31
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SNIP1 Smad nuclear interacting protein 1
SOD3 superoxide dismutase 3, extracellular
SPEG SPEG complex locus
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAG3 stromal antigen 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TMCC2 transmembrane and coiled-coil domain family 2
TRIM66 tripartite motif containing 66
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSC22D4 TSC22 domain family, member 4
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
WNT10B wingless-type MMTV integration site family, member 10B
ZNF222 zinc finger protein 222
ZNF230 zinc finger protein 230
ZNF273 zinc finger protein 273
ZNF33B zinc finger protein 33B
ZNF671 zinc finger protein 671
ZNF862 zinc finger protein 862