meclofenamic acid-2128 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the meclofenamic acid-2128 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACACB acetyl-CoA carboxylase beta
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ANP32A-IT1 ANP32A intronic transcript 1
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BEGAIN brain-enriched guanylate kinase-associated
BMP4 bone morphogenetic protein 4
C10ORF10 chromosome 10 open reading frame 10
C19ORF40 chromosome 19 open reading frame 40
C1QL1 complement component 1, q subcomponent-like 1
C1R complement component 1, r subcomponent
C9ORF40 chromosome 9 open reading frame 40
CCDC186 coiled-coil domain containing 186
CD68 CD68 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC14A cell division cycle 14A
CEP290 centrosomal protein 290kDa
COBL cordon-bleu WH2 repeat protein
CTC1 CTS telomere maintenance complex component 1
DAPK3 death-associated protein kinase 3
DAXX death-domain associated protein
DCAF4 DDB1 and CUL4 associated factor 4
DZIP1 DAZ interacting zinc finger protein 1
ELOVL5 ELOVL fatty acid elongase 5
EPS8L1 EPS8-like 1
FAM49B family with sequence similarity 49, member B
FLJ21369 uncharacterized protein FLJ21369
GPR4 G protein-coupled receptor 4
HEG1 heart development protein with EGF-like domains 1
HIPK2 homeodomain interacting protein kinase 2
HIRA histone cell cycle regulator
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX1 heme oxygenase 1
HOOK1 hook microtubule-tethering protein 1
HOXB5 homeobox B5
IDI2-AS1 IDI2 antisense RNA 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INHBA inhibin, beta A
JUN jun proto-oncogene
KRAS Kirsten rat sarcoma viral oncogene homolog
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LRRN2 leucine rich repeat neuronal 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPT microtubule-associated protein tau
MED14 mediator complex subunit 14
MEF2A myocyte enhancer factor 2A
MGC12488
MIIP migration and invasion inhibitory protein
MTF2 metal response element binding transcription factor 2
MUC3B mucin 3B, cell surface associated
MYO1D myosin ID
NAAA N-acylethanolamine acid amidase
NOL12 nucleolar protein 12
NR2F2 nuclear receptor subfamily 2, group F, member 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PASK PAS domain containing serine/threonine kinase
PCDH11Y protocadherin 11 Y-linked
PCSK7 proprotein convertase subtilisin/kexin type 7
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PILRA paired immunoglobin-like type 2 receptor alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKP1 plakophilin 1
PLK3 polo-like kinase 3
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRB1 proline-rich protein BstNI subfamily 1
PRPH peripherin
PSG4 pregnancy specific beta-1-glycoprotein 4
PWAR5 Prader Willi/Angelman region RNA 5
RALGDS ral guanine nucleotide dissociation stimulator
RBM19 RNA binding motif protein 19
REST RE1-silencing transcription factor
RGS4 regulator of G-protein signaling 4
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SF1 splicing factor 1
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SMG7 SMG7 nonsense mediated mRNA decay factor
SOX13 SRY (sex determining region Y)-box 13
SSBP3 single stranded DNA binding protein 3
TAOK2 TAO kinase 2
TBX19 T-box 19
TDRKH tudor and KH domain containing
TG thyroglobulin
TRIM14 tripartite motif containing 14
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSKU tsukushi, small leucine rich proteoglycan
TTC39A tetratricopeptide repeat domain 39A
VGLL3 vestigial-like family member 3
WDR19 WD repeat domain 19
WFDC2 WAP four-disulfide core domain 2
YIPF6 Yip1 domain family, member 6
ZFHX2 zinc finger homeobox 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF385D zinc finger protein 385D
ZNF512B zinc finger protein 512B

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AFF4 AF4/FMR2 family, member 4
APOLD1 apolipoprotein L domain containing 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATAT1 alpha tubulin acetyltransferase 1
BCL2L2 BCL2-like 2
C16ORF45 chromosome 16 open reading frame 45
C1ORF105 chromosome 1 open reading frame 105
C5ORF45 chromosome 5 open reading frame 45
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCL20 chemokine (C-C motif) ligand 20
CD82 CD82 molecule
CDC45 cell division cycle 45
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CENPJ centromere protein J
CNGB3 cyclic nucleotide gated channel beta 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPVL carboxypeptidase, vitellogenic-like
CTGF connective tissue growth factor
DBF4 DBF4 zinc finger
DBF4B DBF4 zinc finger B
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAL4 dynein, axonemal, light chain 4
DPY19L2P2 DPY19L2 pseudogene 2
EDAR ectodysplasin A receptor
EXOC3 exocyst complex component 3
F3 coagulation factor III (thromboplastin, tissue factor)
FANCF Fanconi anemia, complementation group F
FNTB farnesyltransferase, CAAX box, beta
GALK1 galactokinase 1
GAMT guanidinoacetate N-methyltransferase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH3 G patch domain containing 3
GPR1 G protein-coupled receptor 1
HOXA1 homeobox A1
HOXB9 homeobox B9
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HYAL3 hyaluronoglucosaminidase 3
IGFBP1 insulin-like growth factor binding protein 1
IRAK4 interleukin-1 receptor-associated kinase 4
ISL1 ISL LIM homeobox 1
KIAA1549L KIAA1549-like
KLHL28 kelch-like family member 28
KRT6B keratin 6B, type II
LMAN1 lectin, mannose-binding, 1
LMO7 LIM domain 7
LRP3 low density lipoprotein receptor-related protein 3
LRRC61 leucine rich repeat containing 61
MANBA mannosidase, beta A, lysosomal
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFSD11 major facilitator superfamily domain containing 11
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPY1R neuropeptide Y receptor Y1
NT5M 5',3'-nucleotidase, mitochondrial
ODF2 outer dense fiber of sperm tails 2
OSR2 odd-skipped related transciption factor 2
PODXL2 podocalyxin-like 2
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRR7 proline rich 7 (synaptic)
PSKH1 protein serine kinase H1
QSER1 glutamine and serine rich 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
S1PR1 sphingosine-1-phosphate receptor 1
SALL2 spalt-like transcription factor 2
SCAI suppressor of cancer cell invasion
SCAMP3 secretory carrier membrane protein 3
SCN1B sodium channel, voltage gated, type I beta subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SLC46A3 solute carrier family 46, member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNAP29 synaptosomal-associated protein, 29kDa
SPIDR scaffolding protein involved in DNA repair
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STK16 serine/threonine kinase 16
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM50B transmembrane protein 50B
TMEM8B transmembrane protein 8B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN2 tetraspanin 2
TTC9 tetratricopeptide repeat domain 9
TUBA3C tubulin, alpha 3c
TWISTNB TWIST neighbor
XYLT2 xylosyltransferase II
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
YY2 YY2 transcription factor
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF134 zinc finger protein 134
ZNF141 zinc finger protein 141
ZNF222 zinc finger protein 222
ZNF665 zinc finger protein 665
ZNRD1-AS1 ZNRD1 antisense RNA 1