mast-cell leukemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A leukemia that results_in an overwhelming number of tissue mast cells located_in peripheral blood. (Human Disease Ontology, DOID_9254)
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Genes

70 genes co-occuring with the disease mast-cell leukemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.66375
SH3KBP1 SH3-domain kinase binding protein 1 1.22649
KITLG KIT ligand 1.19489
RASGRP4 RAS guanyl releasing protein 4 1.09251
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 1.05597
LPXN leupaxin 0.988535
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.93207
BTK Bruton agammaglobulinemia tyrosine kinase 0.875738
SETBP1 SET binding protein 1 0.868777
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.865502
CD2 CD2 molecule 0.865093
TNK2 tyrosine kinase, non-receptor, 2 0.817565
LYN LYN proto-oncogene, Src family tyrosine kinase 0.799103
ASMT acetylserotonin O-methyltransferase 0.766759
SORBS1 sorbin and SH3 domain containing 1 0.761047
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.731786
TET2 tet methylcytosine dioxygenase 2 0.695103
FIP1L1 factor interacting with PAPOLA and CPSF1 0.690694
SYT1 synaptotagmin I 0.690293
CD63 CD63 molecule 0.65565
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.649718
PLK2 polo-like kinase 2 0.62728
GRAP2 GRB2-related adaptor protein 2 0.625711
SEPT2 septin 2 0.623751
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.61162
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.589001
KDR kinase insert domain receptor 0.581606
CD34 CD34 molecule 0.580439
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.568775
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.568775
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.561392
SEPT5 septin 5 0.532701
CMA1 chymase 1, mast cell 0.528063
FES FES proto-oncogene, tyrosine kinase 0.517649
FGR FGR proto-oncogene, Src family tyrosine kinase 0.511496
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.505739
SRSF2 serine/arginine-rich splicing factor 2 0.497703
PRODH proline dehydrogenase (oxidase) 1 0.490454
CTTN cortactin 0.421016
VAV1 vav 1 guanine nucleotide exchange factor 0.415398
AXIN2 axin 2 0.413527
FLT4 fms-related tyrosine kinase 4 0.393001
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.374809
CCL3 chemokine (C-C motif) ligand 3 0.371847
NRP1 neuropilin 1 0.361133
CD177 CD177 molecule 0.347511
ASXL1 additional sex combs like transcriptional regulator 1 0.338707
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.33651
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.313552
PLK1 polo-like kinase 1 0.305226
FLT3 fms-related tyrosine kinase 3 0.304864
ALLC allantoicase 0.300894
IFNA2 interferon, alpha 2 0.295851
FLT1 fms-related tyrosine kinase 1 0.28151
MPO myeloperoxidase 0.279724
NTF3 neurotrophin 3 0.274732
PXN paxillin 0.270108
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.270108
CD58 CD58 molecule 0.257005
CCL4 chemokine (C-C motif) ligand 4 0.245396
ETV6 ets variant 6 0.243645
TYRO3 TYRO3 protein tyrosine kinase 0.228679
MITF microphthalmia-associated transcription factor 0.211934
GRB2 growth factor receptor-bound protein 2 0.19582
CCL13 chemokine (C-C motif) ligand 13 0.192657
IL4 interleukin 4 0.187113
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.183248
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.166544
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.166095
CD68 CD68 molecule 0.160948