mast cell neoplasm Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A hematologic cancer that has_material_basis_in mast cells. (Human Disease Ontology, DOID_3664)
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Genes

170 genes co-occuring with the disease mast cell neoplasm in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ZNF185 zinc finger protein 185 (LIM domain) 2.18606
HDC histidine decarboxylase 1.68906
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 1.67638
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 1.62023
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 1.49043
TPH1 tryptophan hydroxylase 1 1.47682
CMA1 chymase 1, mast cell 1.44913
ISM1 isthmin 1, angiogenesis inhibitor 1.43859
IL2 interleukin 2 1.38123
SNHG12 small nucleolar RNA host gene 12 1.24863
MMP10 matrix metallopeptidase 10 1.22692
TSTA3 tissue specific transplantation antigen P35B 1.18755
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.12572
FBXO31 F-box protein 31 1.11351
THY1 Thy-1 cell surface antigen 1.07698
FBXO21 F-box protein 21 0.9898
HLA-B major histocompatibility complex, class I, B 0.97296
STK16 serine/threonine kinase 16 0.957033
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 0.927105
CTRL chymotrypsin-like 0.920498
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.895
RBSN rabenosyn, RAB effector 0.867549
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 0.827409
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.825358
GLCE glucuronic acid epimerase 0.817155
PLA2G2D phospholipase A2, group IID 0.796232
CD4 CD4 molecule 0.765127
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.735027
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.733406
PLA2G1B phospholipase A2, group IB (pancreas) 0.72127
MTSS1 metastasis suppressor 1 0.687891
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.678302
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.670732
CD276 CD276 molecule 0.651694
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.645375
CPA3 carboxypeptidase A3 (mast cell) 0.608494
KITLG KIT ligand 0.604591
PRF1 perforin 1 (pore forming protein) 0.603811
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 0.603811
F2R coagulation factor II (thrombin) receptor 0.60186
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.586276
DHDH dihydrodiol dehydrogenase (dimeric) 0.581996
CTSC cathepsin C 0.58005
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.578494
TPP2 tripeptidyl peptidase II 0.568775
LYZ lysozyme 0.562558
HIST2H2AC histone cluster 2, H2ac 0.545093
HIST2H2AA4 histone cluster 2, H2aa4 0.544705
HIST2H2AA3 histone cluster 2, H2aa3 0.544705
MIXL1 Mix paired-like homeobox 0.532314
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.531541
CD84 CD84 molecule 0.529608
UCKL1 uridine-cytidine kinase 1-like 1 0.517265
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.515725
UCK1 uridine-cytidine kinase 1 0.510344
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.508808
CCDC34 coiled-coil domain containing 34 0.506507
TNF tumor necrosis factor 0.495793
MVD mevalonate (diphospho) decarboxylase 0.479047
FN1 fibronectin 1 0.476772
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.476393
UCK2 uridine-cytidine kinase 2 0.459373
WRNIP1 Werner helicase interacting protein 1 0.45447
HDLBP high density lipoprotein binding protein 0.45447
STK3 serine/threonine kinase 3 0.447311
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.444676
ICAM1 intercellular adhesion molecule 1 0.431144
CCNC cyclin C 0.42139
MYO1G myosin IG 0.416147
HAL histidine ammonia-lyase 0.412405
CD28 CD28 molecule 0.406798
SGPL1 sphingosine-1-phosphate lyase 1 0.406051
PTBP2 polypyrimidine tract binding protein 2 0.401572
DMRT1 doublesex and mab-3 related transcription factor 1 0.396725
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.395235
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.394863
PDYN prodynorphin 0.391513
MSRA methionine sulfoxide reductase A 0.389653
LPO lactoperoxidase 0.383337
STK26 serine/threonine protein kinase 26 0.383337
CD40 CD40 molecule, TNF receptor superfamily member 5 0.381852
SRGN serglycin 0.371847
VIT vitrin 0.368888
MUC4 mucin 4, cell surface associated 0.36704
TET2 tet methylcytosine dioxygenase 2 0.365932
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.365562
SPN sialophorin 0.362609
FIP1L1 factor interacting with PAPOLA and CPSF1 0.361502
PALLD palladin, cytoskeletal associated protein 0.35892
CD80 CD80 molecule 0.355604
AOC3 amine oxidase, copper containing 3 0.349349
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.348246
CD86 CD86 molecule 0.345308
MT2A metallothionein 2A 0.344574
SLAMF1 signaling lymphocytic activation molecule family member 1 0.34384
TMBIM4 transmembrane BAX inhibitor motif containing 4 0.337608
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 0.33066
BAGE2 B melanoma antigen family, member 2 0.325916
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.316819
GSTM2 glutathione S-transferase mu 2 (muscle) 0.31464
HOXB13 homeobox B13 0.313552
CD58 CD58 molecule 0.309204
TMPO thymopoietin 0.308842
CD68 CD68 molecule 0.298371
HPSE heparanase 0.296211
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.295132
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.294772
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.288668
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.282582
MSR1 macrophage scavenger receptor 1 0.280796
SEMG1 semenogelin I 0.278297
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 0.260891
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.260538
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.260184
FASLG Fas ligand (TNF superfamily, member 6) 0.255946
ITK IL2-inducible T-cell kinase 0.254888
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.254888
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.249608
GJA4 gap junction protein, alpha 4, 37kDa 0.245396
NAGA N-acetylgalactosaminidase, alpha- 0.242945
QDPR quinoid dihydropteridine reductase 0.239799
DHPS deoxyhypusine synthase 0.239799
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.237009
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.236312
TAC1 tachykinin, precursor 1 0.236312
PTBP1 polypyrimidine tract binding protein 1 0.234573
TRAC T cell receptor alpha constant 0.21974
AHCY adenosylhomocysteinase 0.213283
PROP1 PROP paired-like homeobox 1 0.210253
ICAM2 intercellular adhesion molecule 2 0.209918
CD34 CD34 molecule 0.208579
F12 coagulation factor XII (Hageman factor) 0.207578
IFNG interferon, gamma 0.198064
AGA aspartylglucosaminidase 0.19742
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.194232
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.193915
PTGDR prostaglandin D2 receptor (DP) 0.191097
PLG plasminogen 0.189859
FADS2 fatty acid desaturase 2 0.189244
CD48 CD48 molecule 0.188022
CD200 CD200 molecule 0.185612
AMY2A amylase, alpha 2A (pancreatic) 0.183835
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.178682
CD2 CD2 molecule 0.177576
NT5E 5'-nucleotidase, ecto (CD73) 0.177576
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.169812
ADK adenosine kinase 0.166768
CSN1S1 casein alpha s1 0.165874
ATP11A ATPase, class VI, type 11A 0.141114
ECE1 endothelin converting enzyme 1 0.14102
PRSS21 protease, serine, 21 (testisin) 0.140936
ICK intestinal cell (MAK-like) kinase 0.140425
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.140391
POMC proopiomelanocortin 0.140246
RICTOR RPTOR independent companion of MTOR, complex 2 0.140069
HAND1 heart and neural crest derivatives expressed 1 0.139756
TPMT thiopurine S-methyltransferase 0.137768
PGRMC1 progesterone receptor membrane component 1 0.137273
MGAM maltase-glucoamylase 0.136851
CLU clusterin 0.136442
CD9 CD9 molecule 0.135996
CD63 CD63 molecule 0.135394
ANK1 ankyrin 1, erythrocytic 0.134666
ERAS ES cell expressed Ras 0.134538
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.133641
CD6 CD6 molecule 0.13326
BMP2 bone morphogenetic protein 2 0.131475
DNAH8 dynein, axonemal, heavy chain 8 0.130079
CD69 CD69 molecule 0.127866
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.127592