marginal zone b-cell lymphoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A B-cell lymphoma that is characterized by initial formation in the marginal zones of lymph tissue. (Human Disease Ontology, DOID_0050748)
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Genes

154 genes co-occuring with the disease marginal zone b-cell lymphoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MALT1 MALT1 paracaspase 2.21324
CD5 CD5 molecule 1.89731
BIRC3 baculoviral IAP repeat containing 3 1.89684
BCL10 B-cell CLL/lymphoma 10 1.73277
BCL6 B-cell CLL/lymphoma 6 1.66375
IGH immunoglobulin heavy locus 1.54318
CCND1 cyclin D1 1.43815
CD19 CD19 molecule 1.31144
IGHV5-51 immunoglobulin heavy variable 5-51 1.24037
FOXP1 forkhead box P1 1.19445
IGHV4-34 immunoglobulin heavy variable 4-34 1.1841
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.18324
TMEM209 transmembrane protein 209 1.12487
PAX5 paired box 5 1.08789
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 1.08495
CD79B CD79b molecule, immunoglobulin-associated beta 1.05976
IGHV3-64 immunoglobulin heavy variable 3-64 1.05639
MAP3K14 mitogen-activated protein kinase kinase kinase 14 1.04083
IGKV3-15 immunoglobulin kappa variable 3-15 1.00499
COPG2 coatomer protein complex, subunit gamma 2 0.976323
CD79A CD79a molecule, immunoglobulin-associated alpha 0.97212
ADAM3A ADAM metallopeptidase domain 3A (pseudogene) 0.97086
PLA2G4D phospholipase A2, group IVD (cytosolic) 0.968761
CARD11 caspase recruitment domain family, member 11 0.963728
IGHV3-74 immunoglobulin heavy variable 3-74 0.95745
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.91308
IGHV3-7 immunoglobulin heavy variable 3-7 0.903621
TCL1A T-cell leukemia/lymphoma 1A 0.896641
PAX2 paired box 2 0.895
AMOTL1 angiomotin like 1 0.892948
IGHV4-39 immunoglobulin heavy variable 4-39 0.878195
NOTCH2 notch 2 0.876557
TP53 tumor protein p53 0.875738
SCAPER S-phase cyclin A-associated protein in the ER 0.875329
SPEN spen family transcriptional repressor 0.866321
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.846669
IGHV3-9 immunoglobulin heavy variable 3-9 0.838066
CD38 CD38 molecule 0.836017
OCIAD1 OCIA domain containing 1 0.826178
RBM15 RNA binding motif protein 15 0.820437
IGHV1-2 immunoglobulin heavy variable 1-2 0.794181
CD22 CD22 molecule 0.792541
IGKV1-39 immunoglobulin kappa variable 1-39 (gene/pseudogene) 0.790492
CD27 CD27 molecule 0.788442
SIRPB1 signal-regulatory protein beta 1 0.750864
NOTCH2NL notch 2 N-terminal like 0.745578
ZC3HC1 zinc finger, C3HC-type containing 1 0.690694
PCDH9 protocadherin 9 0.684292
MYD88 myeloid differentiation primary response 88 0.678701
GPR15 G protein-coupled receptor 15 0.665166
IRF4 interferon regulatory factor 4 0.659611
SOX11 SRY (sex determining region Y)-box 11 0.650903
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.642615
LPXN leupaxin 0.626888
DUSP22 dual specificity phosphatase 22 0.596792
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.596012
FBXO11 F-box protein 11 0.593285
CLLU1 chronic lymphocytic leukemia up-regulated 1 0.590558
DTX1 deltex 1, E3 ubiquitin ligase 0.587833
FAT4 FAT atypical cadherin 4 0.578106
SND1 staphylococcal nuclease and tudor domain containing 1 0.560616
AICDA activation-induced cytidine deaminase 0.55518
IGHV1-69 immunoglobulin heavy variable 1-69 0.54393
IGKV1D-42 immunoglobulin kappa variable 1D-42 (non-functional) 0.538506
NODAL nodal growth differentiation factor 0.524974
TFDP1 transcription factor Dp-1 0.50689
ANXA1 annexin A1 0.504207
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.497703
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.489691
PICALM phosphatidylinositol binding clathrin assembly protein 0.489311
STAB1 stabilin 1 0.480186
CALU calumenin 0.479427
TRRAP transformation/transcription domain-associated protein 0.476772
MTUS1 microtubule associated tumor suppressor 1 0.474877
BCL3 B-cell CLL/lymphoma 3 0.471089
MNDA myeloid cell nuclear differentiation antigen 0.470711
MAML1 mastermind-like 1 (Drosophila) 0.469576
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 0.467306
AGO2 argonaute RISC catalytic component 2 0.465038
JAM3 junctional adhesion molecule 3 0.460129
TRAF3 TNF receptor-associated factor 3 0.456732
TRAF5 TNF receptor-associated factor 5 0.449571
MIR26B microRNA 26b 0.441666
BCR breakpoint cluster region 0.42739
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.424389
JUND jun D proto-oncogene 0.420266
IGKV3-20 immunoglobulin kappa variable 3-20 0.418394
IRF5 interferon regulatory factor 5 0.41727
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.416147
CRNN cornulin 0.393746
GML glycosylphosphatidylinositol anchored molecule like 0.393746
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.385565
CD81 CD81 molecule 0.377031
CXCR5 chemokine (C-X-C motif) receptor 5 0.37555
MIR27B microRNA 27b 0.365193
PTPRJ protein tyrosine phosphatase, receptor type, J 0.361502
CDKN2A cyclin-dependent kinase inhibitor 2A 0.35892
AOC3 amine oxidase, copper containing 3 0.354868
CDK6 cyclin-dependent kinase 6 0.349349
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.344574
CXCR3 chemokine (C-X-C motif) receptor 3 0.331025
PRKCA protein kinase C, alpha 0.328469
CRTC1 CREB regulated transcription coactivator 1 0.327375
DPP8 dipeptidyl-peptidase 8 0.302698
CXCL13 chemokine (C-X-C motif) ligand 13 0.302337
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.300173
CD72 CD72 molecule 0.300173
CLPTM1L CLPTM1-like 0.300173
SEMG1 semenogelin I 0.299092
MAML2 mastermind-like 2 (Drosophila) 0.28831
NCAM1 neural cell adhesion molecule 1 0.285086
CXCL6 chemokine (C-X-C motif) ligand 6 0.28151
ATM ATM serine/threonine kinase 0.275089
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.274376
PDLIM7 PDZ and LIM domain 7 (enigma) 0.273308
TNIP1 TNFAIP3 interacting protein 1 0.271886
MIR100 microRNA 100 0.269043
KMT2B lysine (K)-specific methyltransferase 2B 0.268687
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.267977
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.265849
SETX senataxin 0.259477
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.259124
RAD51C RAD51 paralog C 0.258417
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.252422
HYLS1 hydrolethalus syndrome 1 0.248905
CCND3 cyclin D3 0.241546
STMN1 stathmin 1 0.238752
CUL1 cullin 1 0.225573
CRABP2 cellular retinoic acid binding protein 2 0.218715
NOTCH1 notch 1 0.209248
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.200006
NDN necdin, melanoma antigen (MAGE) family member 0.195501
CDC25B cell division cycle 25B 0.194232
BCL2 B-cell CLL/lymphoma 2 0.177301
MIR21 microRNA 21 0.177029
CD200 CD200 molecule 0.176757
CDK7 cyclin-dependent kinase 7 0.173057
CAV2 caveolin 2 0.170299
PTPRC protein tyrosine phosphatase, receptor type, C 0.163523
DAP death-associated protein 0.160948
ALK anaplastic lymphoma receptor tyrosine kinase 0.160021
IRAK1 interleukin-1 receptor-associated kinase 1 0.159658
CXCL9 chemokine (C-X-C motif) ligand 9 0.144217
MIR223 microRNA 223 0.144134
CD40 CD40 molecule, TNF receptor superfamily member 5 0.144087
EP300 E1A binding protein p300 0.144083
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.143831
SELPLG selectin P ligand 0.143089
ICAM3 intercellular adhesion molecule 3 0.143049
MIR145 microRNA 145 0.142642
MIR146A microRNA 146a 0.142387
C1S complement component 1, s subcomponent 0.141876
FBL fibrillarin 0.141566
CREBBP CREB binding protein 0.141351