| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the maprotiline-6676 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| AGRN | agrin |
| APOC1 | apolipoprotein C-I |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BTG2 | BTG family, member 2 |
| C3 | complement component 3 |
| C8A | complement component 8, alpha polypeptide |
| CABP2 | calcium binding protein 2 |
| CALD1 | caldesmon 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CDH20 | cadherin 20, type 2 |
| CDHR2 | cadherin-related family member 2 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| DENND3 | DENN/MADD domain containing 3 |
| DRD2 | dopamine receptor D2 |
| DUOX2 | dual oxidase 2 |
| EGR1 | early growth response 1 |
| EPHB1 | EPH receptor B1 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| FBRS | fibrosin |
| FGF21 | fibroblast growth factor 21 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FRMD8 | FERM domain containing 8 |
| GDF2 | growth differentiation factor 2 |
| GK | glycerol kinase |
| GSN | gelsolin |
| HIST1H2AL | histone cluster 1, H2al |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HNF1B | HNF1 homeobox B |
| HRG | histidine-rich glycoprotein |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IDS | iduronate 2-sulfatase |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFNA16 | interferon, alpha 16 |
| IL1RN | interleukin 1 receptor antagonist |
| ING4 | inhibitor of growth family, member 4 |
| INSIG1 | insulin induced gene 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLHL22 | kelch-like family member 22 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 |
| KRT24 | keratin 24, type I |
| LDLR | low density lipoprotein receptor |
| LOC100131510 | uncharacterized LOC100131510 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAGEA5 | melanoma antigen family A5 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NNMT | nicotinamide N-methyltransferase |
| NPAS1 | neuronal PAS domain protein 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OGFR | opioid growth factor receptor |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PKN2 | protein kinase N2 |
| PLA2G5 | phospholipase A2, group V |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLIN2 | perilipin 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS11 | regulator of G-protein signaling 11 |
| RHEB | Ras homolog enriched in brain |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPA4 | replication protein A4, 30kDa |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCARB1 | scavenger receptor class B, member 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SPTB | spectrin, beta, erythrocytic |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| SSX7 | synovial sarcoma, X breakpoint 7 |
| SYNJ1 | synaptojanin 1 |
| T | T, brachyury homolog (mouse) |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAS2R10 | taste receptor, type 2, member 10 |
| TFEB | transcription factor EB |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRD | T cell receptor delta locus |
| TUB | tubby bipartite transcription factor |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| ULBP1 | UL16 binding protein 1 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| Symbol | Name |
|---|---|
| AATK | apoptosis-associated tyrosine kinase |
| ACVR2B | activin A receptor, type IIB |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AEN | apoptosis enhancing nuclease |
| AFF4 | AF4/FMR2 family, member 4 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AXIN1 | axin 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BTC | betacellulin |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD82 | CD82 molecule |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CIDEC | cell death-inducing DFFA-like effector c |
| CISH | cytokine inducible SH2-containing protein |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPNE7 | copine VII |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DNM3 | dynamin 3 |
| DSPP | dentin sialophosphoprotein |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FZD3 | frizzled class receptor 3 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GAS8 | growth arrest-specific 8 |
| GMPR | guanosine monophosphate reductase |
| GRAMD1C | GRAM domain containing 1C |
| HDAC11 | histone deacetylase 11 |
| HIST1H1D | histone cluster 1, H1d |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IFNA14 | interferon, alpha 14 |
| IL36RN | interleukin 36 receptor antagonist |
| IL4R | interleukin 4 receptor |
| INO80D | INO80 complex subunit D |
| ITGB7 | integrin, beta 7 |
| KIRREL | kin of IRRE like (Drosophila) |
| KRT37 | keratin 37, type I |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MON1B | MON1 secretory trafficking family member B |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRTN | neurturin |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PODXL2 | podocalyxin-like 2 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
| RFWD3 | ring finger and WD repeat domain 3 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SDC3 | syndecan 3 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMYD5 | SMYD family member 5 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAOK1 | TAO kinase 1 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM212 | transmembrane protein 212 |
| TMSB15A | thymosin beta 15a |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| WDR4 | WD repeat domain 4 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF141 | zinc finger protein 141 |
| ZNF219 | zinc finger protein 219 |
| ZNF239 | zinc finger protein 239 |
| ZNF254 | zinc finger protein 254 |
| ZNF264 | zinc finger protein 264 |
| ZNF276 | zinc finger protein 276 |
| ZNF711 | zinc finger protein 711 |
| ZNF768 | zinc finger protein 768 |
| ZXDC | ZXD family zinc finger C |
