mantle cell lymphoma Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A B-cell lymphocytic neoplasm due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles. (Human Disease Ontology, DOID_0050746)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:0050746
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Genes

65 genes associated with the disease mantle cell lymphoma in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 1.02476
USP10 ubiquitin specific peptidase 10 1.02476
KAT2B K(lysine) acetyltransferase 2B 1.00407
LINC00189 long intergenic non-protein coding RNA 189 0.986376
DCC DCC netrin 1 receptor 0.971169
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.960778
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.951514
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.947208
OGFRL1 opioid growth factor receptor-like 1 0.932777
FRMD8 FERM domain containing 8 0.93103
PCSK6 proprotein convertase subtilisin/kexin type 6 0.911472
IQSEC3 IQ motif and Sec7 domain 3 0.898875
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.896938
MAN1B1 mannosidase, alpha, class 1B, member 1 0.88094
SHROOM3 shroom family member 3 0.877977
LOC146513 uncharacterized LOC146513 0.877977
ZMYND15 zinc finger, MYND-type containing 15 0.871229
TTYH1 tweety family member 1 0.859451
LOC100507195 uncharacterized LOC100507195 0.857354
BTNL2 butyrophilin-like 2 0.84116
ALKBH6 alkB, alkylation repair homolog 6 (E. coli) 0.832379
DOCK1 dedicator of cytokinesis 1 0.826025
CLIP3 CAP-GLY domain containing linker protein 3 0.818753
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.815307
SCARB1 scavenger receptor class B, member 1 0.799531
PTPRO protein tyrosine phosphatase, receptor type, O 0.789217
PAQR5 progestin and adipoQ receptor family member V 0.788564
GPA33 glycoprotein A33 (transmembrane) 0.788239
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.783797
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 0.780437
SP100 SP100 nuclear antigen 0.778649
GTSF1 gametocyte specific factor 1 0.769887
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.767882
FAM13A family with sequence similarity 13, member A 0.764659
DPH6 diphthamine biosynthesis 6 0.762941
MRPL23 mitochondrial ribosomal protein L23 0.754478
FOXP1 forkhead box P1 0.754478
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.748359
PPA2 pyrophosphatase (inorganic) 2 0.734059
DLG2 discs, large homolog 2 (Drosophila) 0.714752
PARK2 parkin RBR E3 ubiquitin protein ligase 0.712959
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.712564
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.711585
PITPNM3 PITPNM family member 3 0.711001
DOCK5 dedicator of cytokinesis 5 0.708319
CDH23 cadherin-related 23 0.705888
DGKI diacylglycerol kinase, iota 0.70172
TMEM222 transmembrane protein 222 0.701015
CEP128 centrosomal protein 128kDa 0.698242
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.692261
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.691618
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.689868
AADACL3 arylacetamide deacetylase-like 3 0.688615
ARID1A AT rich interactive domain 1A (SWI-like) 0.682862
INSC inscuteable homolog (Drosophila) 0.681111
LOXHD1 lipoxygenase homology domains 1 0.678682
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.6784
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.676587
SLIT3 slit homolog 3 (Drosophila) 0.675623
MROH2A maestro heat-like repeat family member 2A 0.675077
RAI1 retinoic acid induced 1 0.674534
MTUS1 microtubule associated tumor suppressor 1 0.67239
ADGRB3 adhesion G protein-coupled receptor B3 0.672258
SASH1 SAM and SH3 domain containing 1 0.669747
ONECUT2 one cut homeobox 2 0.668936