mantle cell lymphoma cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Mantle cell lymphoma is one of the rarest of the non-Hodgkin's lymphomas, comprising about 6% of NHL cases. It is a subtype of B-cell lymphoma, due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004472)
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Genes

163 proteins co-occuring with the tissue mantle cell lymphoma cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CCND1 cyclin D1 2.15649
ZNF280A zinc finger protein 280A 2.01772
SOX11 SRY (sex determining region Y)-box 11 1.43292
JADE3 jade family PHD finger 3 1.42506
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 1.27605
SOX12 SRY (sex determining region Y)-box 12 1.27426
SREK1 splicing regulatory glutamine/lysine-rich protein 1 1.27292
RGS13 regulator of G-protein signaling 13 1.26531
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.2461
MOB3B MOB kinase activator 3B 1.24565
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 1.23717
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.21268
CD5 CD5 molecule 1.16072
SETMAR SET domain and mariner transposase fusion gene 1.15761
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.13723
HDGFRP3 hepatoma-derived growth factor, related protein 3 1.11597
CADM1 cell adhesion molecule 1 1.10314
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 1.09783
ATM ATM serine/threonine kinase 1.04973
BTK Bruton agammaglobulinemia tyrosine kinase 1.04137
TP53 tumor protein p53 1.012
BCL2L1 BCL2-like 1 0.996295
CDK4 cyclin-dependent kinase 4 0.968523
CD19 CD19 molecule 0.936199
XPO1 exportin 1 0.867686
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.867263
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.861785
BAX BCL2-associated X protein 0.857995
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 0.846225
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.834899
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.824849
ROR1 receptor tyrosine kinase-like orphan receptor 1 0.820666
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.807299
DLEU2L deleted in lymphocytic leukemia 2-like 0.793959
CDK9 cyclin-dependent kinase 9 0.766954
BIK BCL2-interacting killer (apoptosis-inducing) 0.759914
CKS1B CDC28 protein kinase regulatory subunit 1B 0.757018
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.741327
IGKV1D-42 immunoglobulin kappa variable 1D-42 (non-functional) 0.703127
ERAP2 endoplasmic reticulum aminopeptidase 2 0.687592
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.681064
EIF4E eukaryotic translation initiation factor 4E 0.67984
CD40 CD40 molecule, TNF receptor superfamily member 5 0.664368
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.661523
SEMG1 semenogelin I 0.6534
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.6534
CERS6 ceramide synthase 6 0.649749
CCND2 cyclin D2 0.649749
LOXL3 lysyl oxidase-like 3 0.638809
SOX4 SRY (sex determining region Y)-box 4 0.635572
IRF4 interferon regulatory factor 4 0.634762
NGDN neuroguidin, EIF4E binding protein 0.624254
SMC1A structural maintenance of chromosomes 1A 0.618603
HOXD8 homeobox D8 0.61699
PARP1 poly (ADP-ribose) polymerase 1 0.61699
LOXL4 lysyl oxidase-like 4 0.605709
GDF1 growth differentiation factor 1 0.605306
CDK7 cyclin-dependent kinase 7 0.601686
MLF1 myeloid leukemia factor 1 0.585224
CCND3 cyclin D3 0.584022
ANXA5 annexin A5 0.58322
RCC1 regulator of chromosome condensation 1 0.579216
GPX7 glutathione peroxidase 7 0.578816
SKP1 S-phase kinase-associated protein 1 0.577615
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.561245
CD40LG CD40 ligand 0.552093
FAF1 Fas (TNFRSF6) associated factor 1 0.550106
ZNF804A zinc finger protein 804A 0.538209
HDAC9 histone deacetylase 9 0.531879
ATG3 autophagy related 3 0.527928
BIRC3 baculoviral IAP repeat containing 3 0.527928
MAP6 microtubule-associated protein 6 0.520041
NEBL nebulette 0.517284
HIST1H1D histone cluster 1, H1d 0.508635
CDK6 cyclin-dependent kinase 6 0.504318
RXRG retinoid X receptor, gamma 0.502357
CDKN2A cyclin-dependent kinase inhibitor 2A 0.497266
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.496874
IL21 interleukin 21 0.486326
AK5 adenylate kinase 5 0.486326
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.485156
MIR17 microRNA 17 0.482428
PTEN phosphatase and tensin homolog 0.478534
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.478145
GDF7 growth differentiation factor 7 0.478145
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.465723
MIR96 microRNA 96 0.463787
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.452584
ARHGAP32 Rho GTPase activating protein 32 0.447961
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.447576
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.444115
TEAD2 TEA domain family member 2 0.434906
DUSP5 dual specificity phosphatase 5 0.430312
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.429547
ALOX5 arachidonate 5-lipoxygenase 0.428401
LYN LYN proto-oncogene, Src family tyrosine kinase 0.426872
MDM4 MDM4, p53 regulator 0.425344
IL22RA1 interleukin 22 receptor, alpha 1 0.411631
CDC37 cell division cycle 37 0.40328
PRMT5 protein arginine methyltransferase 5 0.401007
BRCA2 breast cancer 2, early onset 0.396844
ING1 inhibitor of growth family, member 1 0.396465
CENPF centromere protein F, 350/400kDa 0.391931
KMT2B lysine (K)-specific methyltransferase 2B 0.390421
CCNH cyclin H 0.388535
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.388158
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.377996
CXCR5 chemokine (C-X-C motif) receptor 5 0.372743
ADSS adenylosuccinate synthase 0.37087
FZD2 frizzled class receptor 2 0.361155
DVL2 dishevelled segment polarity protein 2 0.358546
ALDOC aldolase C, fructose-bisphosphate 0.356686
HIC1 hypermethylated in cancer 1 0.351856
HRK harakiri, BCL2 interacting protein 0.34926
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.347038
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.346298
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.346298
CNR1 cannabinoid receptor 1 (brain) 0.341863
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.341126
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.33413
RING1 ring finger protein 1 0.330094
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.329361
WNT3 wingless-type MMTV integration site family, member 3 0.328628
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 0.328262
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.324605
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.323144
MTAP methylthioadenosine phosphorylase 0.318042
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.316951
CD38 CD38 molecule 0.315135
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.311145
CXCL13 chemokine (C-X-C motif) ligand 13 0.309335
LOXL2 lysyl oxidase-like 2 0.306083
AICDA activation-induced cytidine deaminase 0.30464
GLIS2 GLIS family zinc finger 2 0.299601
CHEK2 checkpoint kinase 2 0.293151
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 0.292079
RB1 retinoblastoma 1 0.289939
PRAME preferentially expressed antigen in melanoma 0.289226
MCM8 minichromosome maintenance complex component 8 0.286026
SP100 SP100 nuclear antigen 0.285316
RRM2 ribonucleotide reductase M2 0.280364
PCDH8 protocadherin 8 0.278603
RPS6 ribosomal protein S6 0.277197
FOXC1 forkhead box C1 0.275794
HMGB2 high mobility group box 2 0.2723
LOXL1 lysyl oxidase-like 1 0.269521
PRDM1 PR domain containing 1, with ZNF domain 0.269521
CD37 CD37 molecule 0.267446
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.266413
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.265381
ACVR1 activin A receptor, type I 0.262645
NOTCH1 notch 1 0.261964
LTB lymphotoxin beta (TNF superfamily, member 3) 0.260267
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.253578
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.251279
DBN1 drebrin 1 0.244545
MKI67 marker of proliferation Ki-67 0.23961
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.23604
FLOT1 flotillin 1 0.23604
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.22415
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.223662
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.221291
IGH immunoglobulin heavy locus 0.217139