malignant spindle cell melanoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A melanoma that is most commonly located_in sun-exposed skin and results_in_formation_ of spindle-like shaped cells that have a high recurrence rate even with treatment. (Human Disease Ontology, DOID_3162)
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Genes

67 genes co-occuring with the disease malignant spindle cell melanoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MLANA melan-A 2.03651
FOXO4 forkhead box O4 1.94266
SOX10 SRY (sex determining region Y)-box 10 1.51501
TYR tyrosinase 1.38123
PMEL premelanosome protein 1.3324
MITF microphthalmia-associated transcription factor 1.1635
NGFR nerve growth factor receptor 1.14136
CD34 CD34 molecule 0.875738
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.860999
RREB1 ras responsive element binding protein 1 0.858543
KDM4B lysine (K)-specific demethylase 4B 0.800333
CD68 CD68 molecule 0.787213
SYNM synemin, intermediate filament protein 0.749237
ANO7P1 anoctamin 7 pseudogene 1 0.745172
S100A6 S100 calcium binding protein A6 0.740299
MAP2K2 mitogen-activated protein kinase kinase 2 0.711183
ENO2 enolase 2 (gamma, neuronal) 0.709572
MYOG myogenin (myogenic factor 4) 0.685091
MXI1 MAX interactor 1, dimerization protein 0.646953
SOX5 SRY (sex determining region Y)-box 5 0.635528
WT1 Wilms tumor 1 0.634742
MYOD1 myogenic differentiation 1 0.631991
ARTN artemin 0.63042
NRP2 neuropilin 2 0.595623
SLURP1 secreted LY6/PLAUR domain containing 1 0.590169
CSPG4 chondroitin sulfate proteoglycan 4 0.585497
NES nestin 0.563723
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.558674
S100A1 S100 calcium binding protein A1 0.555956
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.541605
CALD1 caldesmon 1 0.540829
FOXD3 forkhead box D3 0.533088
MAGEA4 melanoma antigen family A4 0.526904
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.511496
EZR ezrin 0.491978
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.478668
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.474877
S100A2 S100 calcium binding protein A2 0.467306
IGF2 insulin-like growth factor 2 0.450324
CCNA1 cyclin A1 0.443171
MAGEA1 melanoma antigen family A1 0.419892
S100B S100 calcium binding protein B 0.407545
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.387794
ANO1 anoctamin 1, calcium activated chloride channel 0.36741
EWSR1 EWS RNA-binding protein 1 0.357814
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.349349
SRY sex determining region Y 0.338341
S100P S100 calcium binding protein P 0.31464
MYB v-myb avian myeloblastosis viral oncogene homolog 0.310652
GAP43 growth associated protein 43 0.301254
B3GAT1 beta-1,3-glucuronyltransferase 1 0.300894
PAX7 paired box 7 0.272597
ANPEP alanyl (membrane) aminopeptidase 0.257711
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.252774
ERCC5 excision repair cross-complementation group 5 0.244345
HBA1 hemoglobin, alpha 1 0.226952
MCAM melanoma cell adhesion molecule 0.225229
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.212271
HBA2 hemoglobin, alpha 2 0.207245
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.187415
CDKN2A cyclin-dependent kinase inhibitor 2A 0.18651
SMO smoothened, frizzled class receptor 0.182957
S100A4 S100 calcium binding protein A4 0.174617
XPA xeroderma pigmentosum, complementation group A 0.174617
SOX9 SRY (sex determining region Y)-box 9 0.16933
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.168617
KRAS Kirsten rat sarcoma viral oncogene homolog 0.157929