male reproductive system disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A reproductive system disease that affects male reproductive organs. (Human Disease Ontology, DOID_48)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:48
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Genes

99 genes associated with the disease male reproductive system disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
PTK2 protein tyrosine kinase 2 0.786268
CHSY1 chondroitin sulfate synthase 1 0.740375
CFB complement factor B 0.672904
HLA-DRA major histocompatibility complex, class II, DR alpha 0.667844
TDRKH tudor and KH domain containing 0.613121
C6ORF10 chromosome 6 open reading frame 10 0.600117
FAT1 FAT atypical cadherin 1 0.583656
FAM155A family with sequence similarity 155, member A 0.517638
BTNL2 butyrophilin-like 2 0.496271
MOBP myelin-associated oligodendrocyte basic protein 0.493456
LOC100289473 cytoskeleton associated protein 2-like pseudogene 0.487532
SOX5 SRY (sex determining region Y)-box 5 0.487532
PTPRD protein tyrosine phosphatase, receptor type, D 0.469271
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.462699
SLCO5A1 solute carrier organic anion transporter family, member 5A1 0.458853
ISPD isoprenoid synthase domain containing 0.44927
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.446685
MARCO macrophage receptor with collagenous structure 0.43886
ESR2 estrogen receptor 2 (ER beta) 0.437794
ANAPC4 anaphase promoting complex subunit 4 0.433897
ASTN2 astrotactin 2 0.43298
NOTCH4 notch 4 0.424868
NTM neurotrimin 0.424191
CRACR2A calcium release activated channel regulator 2A 0.422054
AHCY adenosylhomocysteinase 0.4214
MCPH1 microcephalin 1 0.419214
AOX2P aldehyde oxidase 2 pseudogene 0.41764
DNAH10 dynein, axonemal, heavy chain 10 0.416745
GPA33 glycoprotein A33 (transmembrane) 0.416197
PCSK5 proprotein convertase subtilisin/kexin type 5 0.416069
C9ORF171 chromosome 9 open reading frame 171 0.415365
CNTN4 contactin 4 0.414716
PTAR1 protein prenyltransferase alpha subunit repeat containing 1 0.413665
OR56A4 olfactory receptor, family 56, subfamily A, member 4 0.413612
KDM4C lysine (K)-specific demethylase 4C 0.412334
PHF2P1 PHD finger protein 2 pseudogene 1 0.411924
MACROD2 MACRO domain containing 2 0.41114
CNTN5 contactin 5 0.40944
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.407856
LINGO2 leucine rich repeat and Ig domain containing 2 0.407209
LHFPL3 lipoma HMGIC fusion partner-like 3 0.404978
RPTOR regulatory associated protein of MTOR, complex 1 0.403229
AGBL1 ATP/GTP binding protein-like 1 0.400898
TSNARE1 t-SNARE domain containing 1 0.400169
WWC1 WW and C2 domain containing 1 0.400012
EPSTI1 epithelial stromal interaction 1 (breast) 0.399176
GPR75-ASB3 GPR75-ASB3 readthrough 0.398597
SCHIP1 schwannomin interacting protein 1 0.398526
SHANK1 SH3 and multiple ankyrin repeat domains 1 0.398039
DISP2 dispatched homolog 2 (Drosophila) 0.396908
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.396834
DSCAML1 Down syndrome cell adhesion molecule like 1 0.39654
CDK19 cyclin-dependent kinase 19 0.395757
TMEM35 transmembrane protein 35 0.394228
LOC647323 uncharacterized LOC647323 0.39312
UROC1 urocanate hydratase 1 0.392825
CNOT2 CCR4-NOT transcription complex, subunit 2 0.391692
AVEN apoptosis, caspase activation inhibitor 0.389925
USP8 ubiquitin specific peptidase 8 0.389876
DPF3 D4, zinc and double PHD fingers, family 3 0.388506
ASIC2 acid sensing (proton gated) ion channel 2 0.388014
PCDH7 protocadherin 7 0.387883
ERLEC1 endoplasmic reticulum lectin 1 0.386458
RYR2 ryanodine receptor 2 (cardiac) 0.386378
NELL1 NEL-like 1 (chicken) 0.386378
PDZRN4 PDZ domain containing ring finger 4 0.38614
CSMD1 CUB and Sushi multiple domains 1 0.386101
SDK2 sidekick cell adhesion molecule 2 0.386101
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 0.385521
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 0.385446
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.384742
KTN1 kinectin 1 (kinesin receptor) 0.38445
POU6F2 POU class 6 homeobox 2 0.383826
LOC100288181 uncharacterized LOC100288181 0.382746
LOC339298 uncharacterized LOC339298 0.382602
ASB3 ankyrin repeat and SOCS box containing 3 0.381966
CDCP1 CUB domain containing protein 1 0.381863
PENK proenkephalin 0.381453
FAM169B family with sequence similarity 169, member B 0.381286
LPP LIM domain containing preferred translocation partner in lipoma 0.380823
PRNT prion protein (testis specific) 0.379113
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.377522
PKNOX2 PBX/knotted 1 homeobox 2 0.377065
PEBP4 phosphatidylethanolamine-binding protein 4 0.37696
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 0.376363
STK32C serine/threonine kinase 32C 0.376059
SGSM1 small G protein signaling modulator 1 0.375177
KANK1 KN motif and ankyrin repeat domains 1 0.373997
ZBTB7C zinc finger and BTB domain containing 7C 0.373863
NPHP4 nephronophthisis 4 0.373818
ARHGAP42 Rho GTPase activating protein 42 0.37338
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L 0.372637
PDZD2 PDZ domain containing 2 0.371825
ARMC9 armadillo repeat containing 9 0.371529
SLC35F4 solute carrier family 35, member F4 0.371412
TMPRSS4 transmembrane protease, serine 4 0.371258
TEX36 testis expressed 36 0.370971
FRMD4A FERM domain containing 4A 0.370772
PSAT1 phosphoserine aminotransferase 1 0.337413