male reproductive organ cancer Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A reproductive organ cancer that is manifested in the male genital system. This includes organs such as the penis and scrotum. (Human Disease Ontology, DOID_3856)
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Genes

121 genes associated with the disease male reproductive organ cancer in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ASCL2 achaete-scute family bHLH transcription factor 2 1.83302
KITLG KIT ligand 1.80583
NKX3-1 NK3 homeobox 1 1.76124
MSMB microseminoprotein, beta- 1.73341
TERT telomerase reverse transcriptase 1.53808
ITGA6 integrin, alpha 6 1.47687
CLDN11 claudin 11 1.44416
KLK3 kallikrein-related peptidase 3 1.37597
RGS17 regulator of G-protein signaling 17 1.26228
ZGPAT zinc finger, CCCH-type with G patch domain 1.12703
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 1.11998
VAMP8 vesicle-associated membrane protein 8 1.06123
PDLIM5 PDZ and LIM domain 5 1.05198
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 1.04495
SPRY4 sprouty homolog 4 (Drosophila) 1.02486
FERMT2 fermitin family member 2 1.00628
TET2 tet methylcytosine dioxygenase 2 0.995303
RAD23B RAD23 homolog B (S. cerevisiae) 0.982645
BAK1 BCL2-antagonist/killer 1 0.965481
ZNF652 zinc finger protein 652 0.932337
SIDT1 SID1 transmembrane family, member 1 0.923046
AFM afamin 0.916033
SHBG sex hormone-binding globulin 0.894262
RFX6 regulatory factor X, 6 0.872896
ERICH4 glutamate-rich 4 0.872896
TUBA1C tubulin, alpha 1c 0.830123
DMRT1 doublesex and mab-3 related transcription factor 1 0.817078
MMP7 matrix metallopeptidase 7 0.790827
TBX3 T-box 3 0.790827
MDM4 MDM4, p53 regulator 0.790827
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.790827
RBM19 RNA binding motif protein 19 0.738873
EBF2 early B-cell factor 2 0.73332
CLPTM1L CLPTM1-like 0.724323
POU5F1B POU class 5 homeobox 1B 0.724323
SHROOM2 shroom family member 2 0.69843
RAD51B RAD51 paralog B 0.682635
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 0.682635
WDR11 WD repeat domain 11 0.682635
TRIM8 tripartite motif containing 8 0.661797
ATF7IP activating transcription factor 7 interacting protein 0.65413
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.65413
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.63666
HNF1B HNF1 homeobox B 0.63207
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.602429
FLJ40194 uncharacterized FLJ40194 0.602429
MYEOV myeloma overexpressed 0.602429
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.602429
KLF5 Kruppel-like factor 5 (intestinal) 0.58494
MLPH melanophilin 0.58494
NOTCH4 notch 4 0.561725
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.561725
ARMC2 armadillo repeat containing 2 0.537125
EHBP1 EH domain binding protein 1 0.537125
REEP3 receptor accessory protein 3 0.52461
AR androgen receptor 0.52461
FAM9A family with sequence similarity 9, member A 0.486425
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.486425
MAGED1 melanoma antigen family D1 0.486425
ZBTB38 zinc finger and BTB domain containing 38 0.486425
LMTK2 lemur tyrosine kinase 2 0.486425
VGLL3 vestigial-like family member 3 0.486425
THADA thyroid adenoma associated 0.486425
GSPT2 G1 to S phase transition 2 0.486425
GRHL1 grainyhead-like 1 (Drosophila) 0.464771
FGF10 fibroblast growth factor 10 0.449873
RBBP8NL RBBP8 N-terminal like 0.449873
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.438544
LDAH lipid droplet associated hydrolase 0.414708
FOXP4 forkhead box P4 0.414708
CEP152 centrosomal protein 152kDa 0.403461
KLK15 kallikrein-related peptidase 15 0.403461
CHMP2B charged multivesicular body protein 2B 0.403461
CTBP2 C-terminal binding protein 2 0.368757
CENPE centromere protein E, 312kDa 0.368757
KRT8 keratin 8, type II 0.368757
IRX4 iroquois homeobox 4 0.345945
OTX1 orthodenticle homeobox 1 0.311576
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.297866
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.285417
KIAA1211 KIAA1211 0.285417
PCDH11X protocadherin 11 X-linked 0.264872
SYK spleen tyrosine kinase 0.256228
BAIAP2L1 BAI1-associated protein 2-like 1 0.256228
RNASE9 ribonuclease, RNase A family, 9 (non-active) 0.256228
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 0.256228
ASB14 ankyrin repeat and SOCS box containing 14 0.256228
EYS eyes shut homolog (Drosophila) 0.197766
EVC Ellis van Creveld protein 0.197766
AKAP9 A kinase (PRKA) anchor protein 9 0.197766
ANK2 ankyrin 2, neuronal 0.197766
JAZF1 JAZF zinc finger 1 0.197766
AMIGO2 adhesion molecule with Ig-like domain 2 0.197766
UCK2 uridine-cytidine kinase 2 0.197766
CTNND2 catenin (cadherin-associated protein), delta 2 0.197766
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.197766
ADD2 adducin 2 (beta) 0.197766
TNRC6B trinucleotide repeat containing 6B 0.15771
CHL1 cell adhesion molecule L1-like 0.15771
CD200R1L CD200 receptor 1-like 0.15771
CLVS2 clavesin 2 0.15771
INSC inscuteable homolog (Drosophila) 0.126165
CNTN6 contactin 6 0.126165
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.126165
HNRNPA1P4 heterogeneous nuclear ribonucleoprotein A1 pseudogene 4 0.126165
ABLIM1 actin binding LIM protein 1 0.126165
TNC tenascin C 0.126165
CCDC178 coiled-coil domain containing 178 0.126165
PLCL1 phospholipase C-like 1 0.126165
ACOXL acyl-CoA oxidase-like 0.126165
LACC1 laccase (multicopper oxidoreductase) domain containing 1 0.126165
ZNF280B zinc finger protein 280B 0.126165
ANXA13 annexin A13 0.126165
SETBP1 SET binding protein 1 0.100789
SPATA16 spermatogenesis associated 16 0.100789
C16ORF78 chromosome 16 open reading frame 78 0.100789
POM121L12 POM121 transmembrane nucleoporin-like 12 0.100789
KIF13A kinesin family member 13A 0.100789
FAM124A family with sequence similarity 124A 0.080593
BIK BCL2-interacting killer (apoptosis-inducing) 0.080593
FYCO1 FYVE and coiled-coil domain containing 1 0.064973