mafenide-2124 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mafenide-2124 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARHGAP35 Rho GTPase activating protein 35
ARNT aryl hydrocarbon receptor nuclear translocator
ATXN7L1 ataxin 7-like 1
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
B9D1 B9 protein domain 1
BCAN brevican
BFSP1 beaded filament structural protein 1, filensin
C10ORF10 chromosome 10 open reading frame 10
C4ORF29 chromosome 4 open reading frame 29
CCDC88A coiled-coil domain containing 88A
CD79A CD79a molecule, immunoglobulin-associated alpha
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP162 centrosomal protein 162kDa
CEP72 centrosomal protein 72kDa
CPT1A carnitine palmitoyltransferase 1A (liver)
DAPK3 death-associated protein kinase 3
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EFR3B EFR3 homolog B (S. cerevisiae)
ESRRA estrogen-related receptor alpha
ETV4 ets variant 4
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GOLGA2 golgin A2
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GREM1 gremlin 1, DAN family BMP antagonist
HOOK1 hook microtubule-tethering protein 1
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFI6 interferon, alpha-inducible protein 6
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL6ST interleukin 6 signal transducer
KIAA0485 uncharacterized LOC57235
KIF1C kinesin family member 1C
KIF5C kinesin family member 5C
LIG3 ligase III, DNA, ATP-dependent
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MYH10 myosin, heavy chain 10, non-muscle
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NOP14-AS1 NOP14 antisense RNA 1
NPTXR neuronal pentraxin receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PALMD palmdelphin
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHF3 PHD finger protein 3
PIDD1 p53-induced death domain protein 1
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRR14L proline rich 14-like
PRR4 proline rich 4 (lacrimal)
PTPRR protein tyrosine phosphatase, receptor type, R
PYCR1 pyrroline-5-carboxylate reductase 1
RALGDS ral guanine nucleotide dissociation stimulator
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBL2 retinoblastoma-like 2
REST RE1-silencing transcription factor
RHOT2 ras homolog family member T2
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPL13P5 ribosomal protein L13 pseudogene 5
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1-IT1 RUNX1 intronic transcript 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SARM1 sterile alpha and TIR motif containing 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SETD2 SET domain containing 2
SH3BP2 SH3-domain binding protein 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMC1A structural maintenance of chromosomes 1A
SOAT1 sterol O-acyltransferase 1
SOX12 SRY (sex determining region Y)-box 12
SPIN1 spindlin 1
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TM4SF1 transmembrane 4 L six family member 1
TMEM231 transmembrane protein 231
TRIM62 tripartite motif containing 62
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTC30A tetratricopeptide repeat domain 30A
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UNKL unkempt family zinc finger-like
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VGLL1 vestigial-like family member 1
VIPR2 vasoactive intestinal peptide receptor 2
ZBTB43 zinc finger and BTB domain containing 43
ZC3H7B zinc finger CCCH-type containing 7B
ZFHX3 zinc finger homeobox 3
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF140 zinc finger protein 140
ZNF385D zinc finger protein 385D
ZNF44 zinc finger protein 44
ZNF668 zinc finger protein 668
ZNF76 zinc finger protein 76
ZNF783 zinc finger family member 783
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD17B abhydrolase domain containing 17B
ADAM15 ADAM metallopeptidase domain 15
AFAP1 actin filament associated protein 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AMT aminomethyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARRB2 arrestin, beta 2
ATP7B ATPase, Cu++ transporting, beta polypeptide
BAG4 BCL2-associated athanogene 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C16ORF59 chromosome 16 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
C1ORF105 chromosome 1 open reading frame 105
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCDC130 coiled-coil domain containing 130
CCDC85C coiled-coil domain containing 85C
CDON cell adhesion associated, oncogene regulated
CGREF1 cell growth regulator with EF-hand domain 1
CIR1 corepressor interacting with RBPJ, 1
CLCN5 chloride channel, voltage-sensitive 5
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COBL cordon-bleu WH2 repeat protein
CORO2A coronin, actin binding protein, 2A
DBR1 debranching RNA lariats 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
EFNA3 ephrin-A3
EHD3 EH-domain containing 3
EHF ets homologous factor
EN1 engrailed homeobox 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM53B family with sequence similarity 53, member B
FBRS fibrosin
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GJC1 gap junction protein, gamma 1, 45kDa
GLMN glomulin, FKBP associated protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GOLGA8B golgin A8 family, member B
GPATCH2L G patch domain containing 2-like
GPR1 G protein-coupled receptor 1
GPR176 G protein-coupled receptor 176
GPR39 G protein-coupled receptor 39
GPRASP1 G protein-coupled receptor associated sorting protein 1
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIRA histone cell cycle regulator
HIST1H2BJ histone cluster 1, H2bj
HIST3H2A histone cluster 3, H2a
HOXC5 homeobox C5
HSF2BP heat shock transcription factor 2 binding protein
ICK intestinal cell (MAK-like) kinase
IL17RA interleukin 17 receptor A
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCTD20 potassium channel tetramerization domain containing 20
KIAA0753 KIAA0753
KIAA0754 KIAA0754
KIAA0894 KIAA0894 protein
LINS lines homolog (Drosophila)
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP5L low density lipoprotein receptor-related protein 5-like
MAGEH1 melanoma antigen family H1
MBTD1 mbt domain containing 1
MITF microphthalmia-associated transcription factor
MRPL52 mitochondrial ribosomal protein L52
MXD3 MAX dimerization protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NPFFR1 neuropeptide FF receptor 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAQR6 progestin and adipoQ receptor family member VI
PEX26 peroxisomal biogenesis factor 26
PGAP1 post-GPI attachment to proteins 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNB3 plexin B3
PRAME preferentially expressed antigen in melanoma
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
QSER1 glutamine and serine rich 1
RAB3A RAB3A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RIN1 Ras and Rab interactor 1
RPS17P5 ribosomal protein S17 pseudogene 5
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SNHG20 small nucleolar RNA host gene 20
SNX17 sorting nexin 17
TPCN1 two pore segment channel 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TSPAN8 tetraspanin 8
TSPYL2 TSPY-like 2
VGLL3 vestigial-like family member 3
ZBTB48 zinc finger and BTB domain containing 48
ZNF408 zinc finger protein 408
ZNF606 zinc finger protein 606
ZNF671 zinc finger protein 671
ZNF767P zinc finger family member 767, pseudogene
ZNRD1-AS1 ZNRD1 antisense RNA 1