macrophage Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

431 genes co-occuring with the biological term macrophage in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACAT1 acetyl-CoA acetyltransferase 1
ACE2 angiotensin I converting enzyme 2
ACKR3 atypical chemokine receptor 3
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADORA2A adenosine A2a receptor
ADRBK1 adrenergic, beta, receptor kinase 1
AEBP1 AE binding protein 1
AGER advanced glycosylation end product-specific receptor
AHSG alpha-2-HS-glycoprotein
AIF1 allograft inflammatory factor 1
AIM2 absent in melanoma 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALOX15 arachidonate 15-lipoxygenase
ANGPTL2 angiopoietin-like 2
ANXA6 annexin A6
APCS amyloid P component, serum
APOA1 apolipoprotein A-I
APOBR apolipoprotein B receptor
APOE apolipoprotein E
ATF1 activating transcription factor 1
ATP9B ATPase, class II, type 9B
AZU1 azurocidin 1
BAD BCL2-associated agonist of cell death
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL3 B-cell CLL/lymphoma 3
BIRC5 baculoviral IAP repeat containing 5
BLVRA biliverdin reductase A
BMP2 bone morphogenetic protein 2
BSG basigin (Ok blood group)
CALCA calcitonin-related polypeptide alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMP cathelicidin antimicrobial peptide
CAV1 caveolin 1, caveolae protein, 22kDa
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCL8 chemokine (C-C motif) ligand 8
CCNT1 cyclin T1
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD163 CD163 molecule
CD209 CD209 molecule
CD300LF CD300 molecule-like family member f
CD36 CD36 molecule (thrombospondin receptor)
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD47 CD47 molecule
CD5L CD5 molecule-like
CD68 CD68 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD8A CD8a molecule
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIT1 chitinase 1 (chitotriosidase)
CLEC4E C-type lectin domain family 4, member E
CLEC6A C-type lectin domain family 6, member A
CMA1 chymase 1, mast cell
CNR2 cannabinoid receptor 2 (macrophage)
COL3A1 collagen, type III, alpha 1
COL6A3 collagen, type VI, alpha 3
COPS5 COP9 signalosome subunit 5
CORT cortistatin
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CREM cAMP responsive element modulator
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DCN decorin
DCT dopachrome tautomerase
DDIT3 DNA-damage-inducible transcript 3
DDR1 discoidin domain receptor tyrosine kinase 1
DDT D-dopachrome tautomerase
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DGKG diacylglycerol kinase, gamma 90kDa
DNM2 dynamin 2
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
E2F6 E2F transcription factor 6
EBAG9 estrogen receptor binding site associated, antigen, 9
EDN1 endothelin 1
EDN2 endothelin 2
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ELMO1 engulfment and cell motility 1
ENG endoglin
EP300 E1A binding protein p300
EPRS glutamyl-prolyl-tRNA synthetase
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV3 ets variant 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FEM1A fem-1 homolog a (C. elegans)
FES FES proto-oncogene, tyrosine kinase
FGF18 fibroblast growth factor 18
FGL2 fibrinogen-like 2
FMNL1 formin-like 1
FN1 fibronectin 1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FTMT ferritin mitochondrial
FURIN furin (paired basic amino acid cleaving enzyme)
GAB3 GRB2-associated binding protein 3
GAS6 growth arrest-specific 6
GBA glucosidase, beta, acid
GC group-specific component (vitamin D binding protein)
GDF15 growth differentiation factor 15
GDF5 growth differentiation factor 5
GPBAR1 G protein-coupled bile acid receptor 1
GPC3 glypican 3
GPNMB glycoprotein (transmembrane) nmb
GRN granulin
GSK3B glycogen synthase kinase 3 beta
HAMP hepcidin antimicrobial peptide
HEXB hexosaminidase B (beta polypeptide)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HP haptoglobin
HPSE heparanase
HSF1 heat shock transcription factor 1
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL10 interleukin 10
IL11 interleukin 11
IL12B interleukin 12B
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL17D interleukin 17D
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL21 interleukin 21
IL23A interleukin 23, alpha subunit p19
IL3 interleukin 3
IL6 interleukin 6
ILK integrin-linked kinase
INPPL1 inositol polyphosphate phosphatase-like 1
IRAK1 interleukin-1 receptor-associated kinase 1
IRF4 interferon regulatory factor 4
IRF5 interferon regulatory factor 5
IRF8 interferon regulatory factor 8
ITGA1 integrin, alpha 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
JAG1 jagged 1
JUN jun proto-oncogene
JUND jun D proto-oncogene
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KDR kinase insert domain receptor
KIF9 kinesin family member 9
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLF4 Kruppel-like factor 4 (gut)
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LCAT lecithin-cholesterol acyltransferase
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LIF leukemia inhibitory factor
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIPA lipase A, lysosomal acid, cholesterol esterase
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LYNX1 Ly6/neurotoxin 1
LYZ lysozyme
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MCL1 myeloid cell leukemia 1
MEFV Mediterranean fever
MERTK MER proto-oncogene, tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR106A microRNA 106a
MIR125B1 microRNA 125b-1
MIR125B2 microRNA 125b-2
MIR132 microRNA 132
MIR17 microRNA 17
MIR17HG miR-17-92 cluster host gene
MIR20A microRNA 20a
MIR21 microRNA 21
MIR26A1 microRNA 26a-1
MIR26A2 microRNA 26a-2
MIR451A microRNA 451a
MITF microphthalmia-associated transcription factor
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MRC1 mannose receptor, C type 1
MRC2 mannose receptor, C type 2
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MSR1 macrophage scavenger receptor 1
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC16 mucin 16, cell surface associated
MYD88 myeloid differentiation primary response 88
NAGA N-acetylgalactosaminidase, alpha-
NAMPT nicotinamide phosphoribosyltransferase
NCEH1 neutral cholesterol ester hydrolase 1
NCOA3 nuclear receptor coactivator 3
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NODAL nodal growth differentiation factor
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOV nephroblastoma overexpressed
NPR1 natriuretic peptide receptor 1
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRG1 neuregulin 1
NTN1 netrin 1
OSBPL8 oxysterol binding protein-like 8
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PAEP progestagen-associated endometrial protein
PANX1 pannexin 1
PBK PDZ binding kinase
PCSK5 proprotein convertase subtilisin/kexin type 5
PDGFA platelet-derived growth factor alpha polypeptide
PDGFD platelet derived growth factor D
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEBP1 phosphatidylethanolamine binding protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PF4 platelet factor 4
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G10 phospholipase A2, group X
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLIN2 perilipin 2
PLTP phospholipid transfer protein
PON1 paraoxonase 1
PON2 paraoxonase 2
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCE protein kinase C, epsilon
PRKD1 protein kinase D1
PROS1 protein S (alpha)
PTAFR platelet-activating factor receptor
PTEN phosphatase and tensin homolog
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
QKI QKI, KH domain containing, RNA binding
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RB1 retinoblastoma 1
RETN resistin
RGCC regulator of cell cycle
RHOA ras homolog family member A
RTN4 reticulon 4
SCAP SREBF chaperone
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN5A sodium channel, voltage gated, type V alpha subunit
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SHPK sedoheptulokinase
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOCS3 suppressor of cytokine signaling 3
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPHK1 sphingosine kinase 1
SPI1 Spi-1 proto-oncogene
SPP1 secreted phosphoprotein 1
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAB1 stabilin 1
STAR steroidogenic acute regulatory protein
STARD3 StAR-related lipid transfer (START) domain containing 3
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK11 serine/threonine kinase 11
SYK spleen tyrosine kinase
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TICAM1 toll-like receptor adaptor molecule 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TREM1 triggering receptor expressed on myeloid cells 1
TREM2 triggering receptor expressed on myeloid cells 2
TRIB3 tribbles pseudokinase 3
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSC22D3 TSC22 domain family, member 3
TSPO translocator protein (18kDa)
TXN thioredoxin
TXNIP thioredoxin interacting protein
TYROBP TYRO protein tyrosine kinase binding protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UNC13D unc-13 homolog D (C. elegans)
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VENTX VENT homeobox
VIMP VCP-interacting membrane selenoprotein
VIPR2 vasoactive intestinal peptide receptor 2
VSIG4 V-set and immunoglobulin domain containing 4
WISP1 WNT1 inducible signaling pathway protein 1
WNT5A wingless-type MMTV integration site family, member 5A
XDH xanthine dehydrogenase
YBX1 Y box binding protein 1
ZBP1 Z-DNA binding protein 1
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H12B zinc finger CCCH-type containing 12B
ZC3H12C zinc finger CCCH-type containing 12C
ZC3H12D zinc finger CCCH-type containing 12D
ZFP36 ZFP36 ring finger protein
ZNF175 zinc finger protein 175