mRNA Splicing - Major Pathway Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-72163
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Genes

113 proteins participating in the mRNA Splicing - Major Pathway pathway from the Reactome Pathways dataset.

Symbol Name
ALYREF Aly/REF export factor
BCAS2 breast carcinoma amplified sequence 2
CCAR1 cell division cycle and apoptosis regulator 1
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDC40 cell division cycle 40
CDC5L cell division cycle 5-like
CLP1 cleavage and polyadenylation factor I subunit 1
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTNNBL1 catenin, beta like 1
CWC15 CWC15 spliceosome-associated protein
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
EFTUD2 elongation factor Tu GTP binding domain containing 2
FUS FUS RNA binding protein
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HSPA8 heat shock 70kDa protein 8
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
PABPN1 poly(A) binding protein, nuclear 1
PAPOLA poly(A) polymerase alpha
PCBP1 poly(rC) binding protein 1
PCBP2 poly(rC) binding protein 2
PCF11 PCF11 cleavage and polyadenylation factor subunit
PHF5A PHD finger protein 5A
PLRG1 pleiotropic regulator 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PRPF19 pre-mRNA processing factor 19
PRPF4 pre-mRNA processing factor 4
PRPF6 pre-mRNA processing factor 6
PRPF8 pre-mRNA processing factor 8
PTBP1 polypyrimidine tract binding protein 1
RBM5 RNA binding motif protein 5
RBM8A RNA binding motif protein 8A
RBMX RNA binding motif protein, X-linked
RNPS1 RNA binding protein S1, serine-rich domain
SF3A1 splicing factor 3a, subunit 1, 120kDa
SF3A2 splicing factor 3a, subunit 2, 66kDa
SF3A3 splicing factor 3a, subunit 3, 60kDa
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SF3B3 splicing factor 3b, subunit 3, 130kDa
SF3B4 splicing factor 3b, subunit 4, 49kDa
SF3B5 splicing factor 3b, subunit 5, 10kDa
SF3B6 splicing factor 3b, subunit 6, 14kDa
SMC1A structural maintenance of chromosomes 1A
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SNRPF small nuclear ribonucleoprotein polypeptide F
SNRPG small nuclear ribonucleoprotein polypeptide G
SRRM1 serine/arginine repetitive matrix 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF11 serine/arginine-rich splicing factor 11
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF4 serine/arginine-rich splicing factor 4
SRSF5 serine/arginine-rich splicing factor 5
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
SRSF9 serine/arginine-rich splicing factor 9
SUGP1 SURP and G patch domain containing 1
TXNL4A thioredoxin-like 4A
U2AF1 U2 small nuclear RNA auxiliary factor 1
U2AF2 U2 small nuclear RNA auxiliary factor 2
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
YBX1 Y box binding protein 1