lysosomal Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

274 genes co-occuring with the biological term lysosomal in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACP2 acid phosphatase 2, lysosomal
ACVR1B activin A receptor, type IB
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
APOE apolipoprotein E
APOL1 apolipoprotein L, 1
APP amyloid beta (A4) precursor protein
ARF6 ADP-ribosylation factor 6
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL8A ADP-ribosylation factor-like 8A
ARSA arylsulfatase A
ARSB arylsulfatase B
ARSG arylsulfatase G
ARSK arylsulfatase family, member K
ATP13A2 ATPase type 13A2
AXL AXL receptor tyrosine kinase
BACE1 beta-site APP-cleaving enzyme 1
BAMBI BMP and activin membrane-bound inhibitor
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BIRC2 baculoviral IAP repeat containing 2
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BST2 bone marrow stromal cell antigen 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAPN1 calpain 1, (mu/I) large subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD1D CD1d molecule
CD209 CD209 molecule
CD247 CD247 molecule
CD4 CD4 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD86 CD86 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CENPJ centromere protein J
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHM choroideremia (Rab escort protein 1)
CHUK conserved helix-loop-helix ubiquitous kinase
CLCN7 chloride channel, voltage-sensitive 7
CLDN16 claudin 16
CLN3 ceroid-lipofuscinosis, neuronal 3
CLN5 ceroid-lipofuscinosis, neuronal 5
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CSF3R colony stimulating factor 3 receptor (granulocyte)
CST3 cystatin C
CTSB cathepsin B
CTSD cathepsin D
CTSF cathepsin F
CTSG cathepsin G
CTSK cathepsin K
CTSL cathepsin L
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DIRC2 disrupted in renal carcinoma 2
DRAM1 DNA-damage regulated autophagy modulator 1
DRAM2 DNA-damage regulated autophagy modulator 2
DTX3 deltex 3, E3 ubiquitin ligase
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EHD3 EH-domain containing 3
EHD4 EH-domain containing 4
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELF2 E74-like factor 2 (ets domain transcription factor)
EPDR1 ependymin related 1
EPHB1 EPH receptor B1
ERBB2 erb-b2 receptor tyrosine kinase 2
EXTL2 exostosin-like glycosyltransferase 2
EXTL3 exostosin-like glycosyltransferase 3
F2R coagulation factor II (thrombin) receptor
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FLNA filamin A, alpha
FLOT1 flotillin 1
GAA glucosidase, alpha; acid
GABARAP GABA(A) receptor-associated protein
GAK cyclin G associated kinase
GALNS galactosamine (N-acetyl)-6-sulfatase
GAS6 growth arrest-specific 6
GBA glucosidase, beta, acid
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIPC1 GIPC PDZ domain containing family, member 1
GLA galactosidase, alpha
GLB1 galactosidase, beta 1
GNLY granulysin
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit
GRN granulin
GUSB glucuronidase, beta
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAMP hepcidin antimicrobial peptide
HAVCR1 hepatitis A virus cellular receptor 1
HCK HCK proto-oncogene, Src family tyrosine kinase
HEXA hexosaminidase A (alpha polypeptide)
HEXB hexosaminidase B (beta polypeptide)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-C major histocompatibility complex, class I, C
HOXB4 homeobox B4
HPSE heparanase
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
HYAL2 hyaluronoglucosaminidase 2
IFI30 interferon, gamma-inducible protein 30
IGF2R insulin-like growth factor 2 receptor
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL6ST interleukin 6 signal transducer
ITCH itchy E3 ubiquitin protein ligase
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIF2A kinesin heavy chain member 2A
KIF2C kinesin family member 2C
KIF5B kinesin family member 5B
KISS1R KISS1 receptor
KRAS Kirsten rat sarcoma viral oncogene homolog
L1CAM L1 cell adhesion molecule
LAG3 lymphocyte-activation gene 3
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LAPTM4B lysosomal protein transmembrane 4 beta
LDLR low density lipoprotein receptor
LGALS8 lectin, galactoside-binding, soluble, 8
LIPA lipase A, lysosomal acid, cholesterol esterase
LMBRD1 LMBR1 domain containing 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LRRK2 leucine-rich repeat kinase 2
LYST lysosomal trafficking regulator
M6PR mannose-6-phosphate receptor (cation dependent)
MAP1S microtubule-associated protein 1S
MAPK8 mitogen-activated protein kinase 8
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MCOLN1 mucolipin 1
MFSD8 major facilitator superfamily domain containing 8
MINPP1 multiple inositol-polyphosphate phosphatase 1
MPL MPL proto-oncogene, thrombopoietin receptor
MRC2 mannose receptor, C type 2
MT3 metallothionein 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYLIP myosin regulatory light chain interacting protein
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAGA N-acetylgalactosaminidase, alpha-
NAGLU N-acetylglucosaminidase, alpha
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEU1 sialidase 1 (lysosomal sialidase)
NEU4 sialidase 4
NLRP3 NLR family, pyrin domain containing 3
NMB neuromedin B
NPC1 Niemann-Pick disease, type C1
NPC2 Niemann-Pick disease, type C2
NSFL1C NSFL1 (p97) cofactor (p47)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PACS2 phosphofurin acidic cluster sorting protein 2
PAQR8 progestin and adipoQ receptor family member VIII
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD6IP programmed cell death 6 interacting protein
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PLA2G15 phospholipase A2, group XV
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PPT1 palmitoyl-protein thioesterase 1
PPT2 palmitoyl-protein thioesterase 2
PRNP prion protein
PSAP prosaposin
PSEN1 presenilin 1
PSIP1 PC4 and SFRS1 interacting protein 1
PTAFR platelet-activating factor receptor
RAB27A RAB27A, member RAS oncogene family
RAB34 RAB34, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RHOH ras homolog family member H
RILP Rab interacting lysosomal protein
RNASET2 ribonuclease T2
RNF11 ring finger protein 11
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RRAGB Ras-related GTP binding B
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCARB2 scavenger receptor class B, member 2
SCPEP1 serine carboxypeptidase 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX1 sorting nexin 1
SNX17 sorting nexin 17
SNX27 sorting nexin family member 27
SNX3 sorting nexin 3
SORT1 sortilin 1
SPATA18 spermatogenesis associated 18
SPHK1 sphingosine kinase 1
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAMBP STAM binding protein
STS steroid sulfatase (microsomal), isozyme S
STX5 syntaxin 5
SYK spleen tyrosine kinase
TBC1D15 TBC1 domain family, member 15
TFE3 transcription factor binding to IGHM enhancer 3
TFEB transcription factor EB
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
TLR3 toll-like receptor 3
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMEM106B transmembrane protein 106B
TMEM192 transmembrane protein 192
TMEM9 transmembrane protein 9
TNF tumor necrosis factor
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TP53 tumor protein p53
TPD52 tumor protein D52
TPP1 tripeptidyl peptidase I
TYK2 tyrosine kinase 2
UBE4B ubiquitination factor E4B
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ULBP2 UL16 binding protein 2
USP8 ubiquitin specific peptidase 8
UTRN utrophin
VAMP7 vesicle-associated membrane protein 7
VEGFA vascular endothelial growth factor A
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
WNK4 WNK lysine deficient protein kinase 4
ZFYVE9 zinc finger, FYVE domain containing 9