lymphomas Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas.|A cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs.|A general term for various neoplastic diseases of the lymphoid tissue.|Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease. (Experimental Factor Ontology, EFO_0000574)
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Genes

277 genes co-occuring with the biological term lymphomas in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AGA aspartylglucosaminidase
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ANPEP alanyl (membrane) aminopeptidase
AURKA aurora kinase A
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCL7A B-cell CLL/lymphoma 7A
BECN1 beclin 1, autophagy related
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BLNK B-cell linker
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD2 bromodomain containing 2
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL17 chemokine (C-C motif) ligand 17
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CCR9 chemokine (C-C motif) receptor 9
CD19 CD19 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD33 CD33 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD7 CD7 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD99 CD99 molecule
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHEK2 checkpoint kinase 2
CNR2 cannabinoid receptor 2 (macrophage)
CORO1C coronin, actin binding protein, 1C
CT45A1 cancer/testis antigen family 45, member A1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
DAPK1 death-associated protein kinase 1
DIABLO diablo, IAP-binding mitochondrial protein
DICER1 dicer 1, ribonuclease type III
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPP4 dipeptidyl-peptidase 4
DPYD dihydropyrimidine dehydrogenase
E2F1 E2F transcription factor 1
EGF epidermal growth factor
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF4E eukaryotic translation initiation factor 4E
ELAVL1 ELAV like RNA binding protein 1
EPAS1 endothelial PAS domain protein 1
EPHA7 EPH receptor A7
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXO10 F-box protein 10
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCRL4 Fc receptor-like 4
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FOXO3 forkhead box O3
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FYN FYN proto-oncogene, Src family tyrosine kinase
GCSAM germinal center-associated, signaling and motility
GZMM granzyme M (lymphocyte met-ase 1)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HNF1A HNF1 homeobox A
HRK harakiri, BCL2 interacting protein
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFN1@ interferon, type 1, cluster
IGES immunoglobulin E concentration, serum
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGH immunoglobulin heavy locus
IGKV@ immunoglobulin kappa variable cluster
IGLV@ immunoglobulin lambda variable cluster
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL17A interleukin 17A
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL4I1 interleukin 4 induced 1
IL5 interleukin 5
INCENP inner centromere protein antigens 135/155kDa
IRF3 interferon regulatory factor 3
IRF4 interferon regulatory factor 4
IRF5 interferon regulatory factor 5
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITK IL2-inducible T-cell kinase
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JAM3 junctional adhesion molecule 3
JUNB jun B proto-oncogene
KDR kinase insert domain receptor
KIAA1524 KIAA1524
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHDC8B kelch domain containing 8B
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LDHA lactate dehydrogenase A
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LITAF lipopolysaccharide-induced TNF factor
LMO2 LIM domain only 2 (rhombotin-like 1)
LYN LYN proto-oncogene, Src family tyrosine kinase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MALT1 MALT1 paracaspase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MCL1 myeloid cell leukemia 1
MGMT O-6-methylguanine-DNA methyltransferase
MIR125B1 microRNA 125b-1
MIR125B2 microRNA 125b-2
MIR127 microRNA 127
MIR155 microRNA 155
MIR16-1 microRNA 16-1
MIR17 microRNA 17
MIR21 microRNA 21
MIR29A microRNA 29a
MIRLET7A1 microRNA let-7a-1
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MNDA myeloid cell nuclear differentiation antigen
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYD88 myeloid differentiation primary response 88
NAMPT nicotinamide phosphoribosyltransferase
NAPRT nicotinate phosphoribosyltransferase
NCAM1 neural cell adhesion molecule 1
NCL nucleolin
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOTCH1 notch 1
NOTCH2 notch 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRP1 neuropilin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAX5 paired box 5
PAX7 paired box 7
PBK PDZ binding kinase
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDCD2 programmed cell death 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLK1 polo-like kinase 1
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
POLM polymerase (DNA directed), mu
PON1 paraoxonase 1
PPP4R1 protein phosphatase 4, regulatory subunit 1
PRDM1 PR domain containing 1, with ZNF domain
PRDM2 PR domain containing 2, with ZNF domain
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK6 protein tyrosine kinase 6
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PVT1 Pvt1 oncogene (non-protein coding)
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOA ras homolog family member A
RHOH ras homolog family member H
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SATB1 SATB homeobox 1
SEC31A SEC31 homolog A (S. cerevisiae)
SELPLG selectin P ligand
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SIRT7 sirtuin 7
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SOCS1 suppressor of cytokine signaling 1
SOX11 SRY (sex determining region Y)-box 11
SPRY2 sprouty homolog 2 (Drosophila)
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK39 serine threonine kinase 39
SYK spleen tyrosine kinase
TBX21 T-box 21
TCF3 transcription factor 3
TCL1A T-cell leukemia/lymphoma 1A
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TP53 tumor protein p53
TP73 tumor protein p73
TRAF2 TNF receptor-associated factor 2
TRD T cell receptor delta locus
TRG T cell receptor gamma locus
TTK TTK protein kinase
TYMP thymidine phosphorylase
UBE3A ubiquitin protein ligase E3A
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VPREB3 pre-B lymphocyte 3
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YY1 YY1 transcription factor
ZBTB16 zinc finger and BTB domain containing 16
ZFYVE9 zinc finger, FYVE domain containing 9