lymphoblastic leukemia Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A leukemia that has_material_basis_in lymphoblasts (immature white blood cells). (Human Disease Ontology, DOID_1037)
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Genes

51 genes associated with the disease lymphoblastic leukemia in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
IRF4 interferon regulatory factor 4 1.37597
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.33613
BAK1 BCL2-antagonist/killer 1 1.09962
ARID5B AT rich interactive domain 5B (MRF1-like) 1.09588
RPLP1 ribosomal protein, large, P1 0.774217
ACOXL acyl-CoA oxidase-like 0.69843
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.602429
IRF8 interferon regulatory factor 8 0.58494
PRKD2 protein kinase D2 0.572184
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.544585
PYGL phosphorylase, glycogen, liver 0.544585
TP63 tumor protein p63 0.5306
OR5R1 olfactory receptor, family 5, subfamily R, member 1 (gene/pseudogene) 0.464771
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 0.414708
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.408752
MTAP methylthioadenosine phosphorylase 0.403461
CDKN2A cyclin-dependent kinase inhibitor 2A 0.403461
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.403461
MYRIP myosin VIIA and Rab interacting protein 0.368757
SP140 SP140 nuclear body protein 0.368757
ZNF221 zinc finger protein 221 0.345945
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 0.345945
FKRP fukutin related protein 0.327313
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 0.274608
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.264872
PTPRJ protein tyrosine phosphatase, receptor type, J 0.256228
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.256228
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.256228
SKA1 spindle and kinetochore associated complex subunit 1 0.197766
INTS10 integrator complex subunit 10 0.197766
TBXAS1 thromboxane A synthase 1 (platelet) 0.197766
RYR2 ryanodine receptor 2 (cardiac) 0.197766
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.15771
PPP4R4 protein phosphatase 4, regulatory subunit 4 0.15771
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 0.126165
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.126165
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.126165
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.126165
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.100789
PDE4B phosphodiesterase 4B, cAMP-specific 0.100789
CENPF centromere protein F, 350/400kDa 0.100789
RIT2 Ras-like without CAAX 2 0.100789
BRMS1L breast cancer metastasis-suppressor 1-like 0.100789
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 0.080593
GCSAML germinal center-associated, signaling and motility-like 0.064973
CFHR2 complement factor H-related 2 0.064973
TIGAR TP53 induced glycolysis regulatory phosphatase 0.052255
NPFFR1 neuropeptide FF receptor 1 0.052255
DISC1 disrupted in schizophrenia 1 0.043246
PARD3 par-3 family cell polarity regulator 0.043246
METTL4 methyltransferase like 4 0.043246