lymphatic system disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description An immune system disease that is located_in the lymphatic system. (Human Disease Ontology, DOID_75)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:75
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Genes

123 genes associated with the disease lymphatic system disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
ITPKC inositol-trisphosphate 3-kinase C 1.1703
BLK BLK proto-oncogene, Src family tyrosine kinase 1.09718
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.980528
CSMD1 CUB and Sushi multiple domains 1 0.941946
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.680227
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.638262
CENPU centromere protein U 0.624472
SLC35F5 solute carrier family 35, member F5 0.592065
IRF8 interferon regulatory factor 8 0.576579
IL1RAP interleukin 1 receptor accessory protein 0.542867
TECRL trans-2,3-enoyl-CoA reductase-like 0.539904
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 0.532882
ZSCAN25 zinc finger and SCAN domain containing 25 0.532882
BUD31 BUD31 homolog (S. cerevisiae) 0.532882
SLC39A11 solute carrier family 39, member 11 0.528352
MED30 mediator complex subunit 30 0.519576
HLA-DRA major histocompatibility complex, class II, DR alpha 0.517312
LDLRAD3 low density lipoprotein receptor class A domain containing 3 0.509179
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.497255
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.496271
CADPS Ca++-dependent secretion activator 0.491552
DNM3 dynamin 3 0.490531
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.487607
PELI1 pellino E3 ubiquitin protein ligase 1 0.484681
ZFHX3 zinc finger homeobox 3 0.484681
SLC39A13 solute carrier family 39 (zinc transporter), member 13 0.48441
GCOM1 GRINL1A complex locus 1 0.483564
CLEC3A C-type lectin domain family 3, member A 0.483564
PTCD1 pentatricopeptide repeat domain 1 0.483091
ZNF655 zinc finger protein 655 0.483091
TFCP2 transcription factor CP2 0.482534
TMEM233 transmembrane protein 233 0.481709
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.481644
ZNF717 zinc finger protein 717 0.481579
MLIP muscular LMNA-interacting protein 0.481515
CD40 CD40 molecule, TNF receptor superfamily member 5 0.481217
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.479319
RIMS2 regulating synaptic membrane exocytosis 2 0.479226
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.478888
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.476861
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.476477
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.475825
NCK2 NCK adaptor protein 2 0.475738
TLL1 tolloid-like 1 0.474236
VIL1 villin 1 0.474192
DEC1 deleted in esophageal cancer 1 0.474192
FHIT fragile histidine triad 0.474046
RAB4B RAB4B, member RAS oncogene family 0.474046
SMC5 structural maintenance of chromosomes 5 0.473946
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.47379
FSTL4 follistatin-like 4 0.473623
BTBD1 BTB (POZ) domain containing 1 0.473391
LOC100130301 0.472241
HLA-DOB major histocompatibility complex, class II, DO beta 0.471611
SNRPA small nuclear ribonucleoprotein polypeptide A 0.471243
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.471119
SHC4 SHC (Src homology 2 domain containing) family, member 4 0.471064
LOC100287329 uncharacterized LOC100287329 0.471042
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L 0.470932
PXDNL peroxidasin-like 0.470888
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 0.470525
ZNF536 zinc finger protein 536 0.470494
CLCN3 chloride channel, voltage-sensitive 3 0.470308
LOC285692 uncharacterized LOC285692 0.470267
ITFG1 integrin alpha FG-GAP repeat containing 1 0.470075
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.470025
EBF2 early B-cell factor 2 0.470015
DLG2 discs, large homolog 2 (Drosophila) 0.469233
PROKR2 prokineticin receptor 2 0.466757
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.465442
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.463376
ROR2 receptor tyrosine kinase-like orphan receptor 2 0.462725
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.462274
RBP2 retinol binding protein 2, cellular 0.461787
COL4A2 collagen, type IV, alpha 2 0.461119
HNF1B HNF1 homeobox B 0.460971
NUMBL numb homolog (Drosophila)-like 0.460442
C6ORF10 chromosome 6 open reading frame 10 0.459802
PDGFD platelet derived growth factor D 0.458544
ERBB4 erb-b2 receptor tyrosine kinase 4 0.458154
RELN reelin 0.458027
NEB nebulin 0.457099
RDH16 retinol dehydrogenase 16 (all-trans) 0.457099
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 0.456398
TTC1 tetratricopeptide repeat domain 1 0.456355
EGLN2 egl-9 family hypoxia-inducible factor 2 0.455936
MYRIP myosin VIIA and Rab interacting protein 0.455529
CADM1 cell adhesion molecule 1 0.455211
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.45441
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.454009
HEG1 heart development protein with EGF-like domains 1 0.453937
DLK1 delta-like 1 homolog (Drosophila) 0.453653
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.453653
LOC100507291 uncharacterized LOC100507291 0.45317
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.452001
ERAP1 endoplasmic reticulum aminopeptidase 1 0.45197
FLT1 fms-related tyrosine kinase 1 0.451059
HCG23 HLA complex group 23 (non-protein coding) 0.450706
BMPER BMP binding endothelial regulator 0.450429
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.449788
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.449788
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.449234
PARK2 parkin RBR E3 ubiquitin protein ligase 0.44917
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 0.448119
HEATR5B HEAT repeat containing 5B 0.447501
PRICKLE1 prickle homolog 1 (Drosophila) 0.446547
FILIP1L filamin A interacting protein 1-like 0.445363
LOC100287225 uncharacterized LOC100287225 0.445313
SCGN secretagogin, EF-hand calcium binding protein 0.444282
MTCH2 mitochondrial carrier 2 0.444022
ZFPM2 zinc finger protein, FOG family member 2 0.442176
FAM184A family with sequence similarity 184, member A 0.441867
CLEC4A C-type lectin domain family 4, member A 0.43996
NCOA5 nuclear receptor coactivator 5 0.439843
KLC1 kinesin light chain 1 0.439592
LRRC16A leucine rich repeat containing 16A 0.438584
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.438566
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.434923
CCDC186 coiled-coil domain containing 186 0.429222
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.412327
HRH2 histamine receptor H2 0.402949
TDRD1 tudor domain containing 1 0.401617
FAM167A family with sequence similarity 167, member A 0.396653