lymphatic system cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An immune system cancer that is located_in the lymphatic system and is characterized by uncontrolled cellular proliferation of lymphoid tissue. (Human Disease Ontology, DOID_0060073)
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Genes

361 genes co-occuring with the disease lymphatic system cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ALK anaplastic lymphoma receptor tyrosine kinase 2.35511
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 1.83863
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.64666
BCL6 B-cell CLL/lymphoma 6 1.61128
ASRGL1 asparaginase like 1 1.35202
LYZ lysozyme 1.35028
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.30882
FGF19 fibroblast growth factor 19 1.09503
CD68 CD68 molecule 1.08663
TPM3 tropomyosin 3 1.08118
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 1.0795
CD8BP CD8b molecule pseudogene 1.04672
LTK leukocyte receptor tyrosine kinase 1.04588
CD5 CD5 molecule 1.03872
DACH1 dachshund family transcription factor 1 1.00794
CRNN cornulin 0.975482
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.967083
NCAM1 neural cell adhesion molecule 1 0.95369
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.951604
CD4 CD4 molecule 0.951187
TP53 tumor protein p53 0.882292
LCK LCK proto-oncogene, Src family tyrosine kinase 0.867959
PHYH phytanoyl-CoA 2-hydroxylase 0.846669
CD79A CD79a molecule, immunoglobulin-associated alpha 0.846259
PTPRC protein tyrosine phosphatase, receptor type, C 0.837246
BCL2 B-cell CLL/lymphoma 2 0.832329
CDKL3 cyclin-dependent kinase-like 3 0.80977
PROX1 prospero homeobox 1 0.803616
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.788852
PDLIM7 PDZ and LIM domain 7 (enigma) 0.787623
EML4 echinoderm microtubule associated protein like 4 0.785574
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.767167
ADAM3A ADAM metallopeptidase domain 3A (pseudogene) 0.758193
GRB2 growth factor receptor-bound protein 2 0.748017
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.717232
TFG TRK-fused gene 0.716828
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.699517
PAX5 paired box 5 0.685091
PTPRB protein tyrosine phosphatase, receptor type, B 0.673917
CD22 CD22 molecule 0.670333
SCAPER S-phase cyclin A-associated protein in the ER 0.665563
PRF1 perforin 1 (pore forming protein) 0.661197
RFXANK regulatory factor X-associated ankyrin-containing protein 0.659611
AKAP17A A kinase (PRKA) anchor protein 17A 0.648138
CD19 CD19 molecule 0.646559
RAB35 RAB35, member RAS oncogene family 0.641827
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.637495
F8 coagulation factor VIII, procoagulant component 0.637102
IRF4 interferon regulatory factor 4 0.635921
IL2 interleukin 2 0.635135
GPR176 G protein-coupled receptor 176 0.634742
CD7 CD7 molecule 0.632777
HOXC6 homeobox C6 0.619442
HYLS1 hydrolethalus syndrome 1 0.612401
BCL10 B-cell CLL/lymphoma 10 0.588222
ACPP acid phosphatase, prostate 0.587833
PIDD1 p53-induced death domain protein 1 0.58433
DCTD dCMP deaminase 0.578106
IL2RA interleukin 2 receptor, alpha 0.574605
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.562169
GAGE12G G antigen 12G 0.560616
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 0.557509
NFE2L3 nuclear factor, erythroid 2-like 3 0.552851
MMP10 matrix metallopeptidase 10 0.549359
SIRPB1 signal-regulatory protein beta 1 0.546256
SFPQ splicing factor proline/glutamine-rich 0.53657
HOXC5 homeobox C5 0.529994
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.526904
HECA headcase homolog (Drosophila) 0.524974
UBN1 ubinuclein 1 0.515725
RBAK RB-associated KRAB zinc finger 0.509959
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.508424
ZNF652 zinc finger protein 652 0.50689
ACO1 aconitase 1, soluble 0.50459
TEK TEK tyrosine kinase, endothelial 0.503824
TMOD1 tropomodulin 1 0.503058
TRAF1 TNF receptor-associated factor 1 0.502292
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.496175
CCND1 cyclin D1 0.485505
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.477151
TFRC transferrin receptor 0.467306
IPO8 importin 8 0.462016
SH2D1A SH2 domain containing 1A 0.460506
BATF3 basic leucine zipper transcription factor, ATF-like 3 0.460506
CCND3 cyclin D3 0.451078
GUCA1B guanylate cyclase activator 1B (retina) 0.449194
CD52 CD52 molecule 0.448441
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.448441
HOXA3 homeobox A3 0.446558
CD44 CD44 molecule (Indian blood group) 0.441666
MECOM MDS1 and EVI1 complex locus 0.43753
GAGE12F G antigen 12F 0.436402
SYCP1 synaptonemal complex protein 1 0.435651
LUZP4 leucine zipper protein 4 0.424765
B2M beta-2-microglobulin 0.420266
PTN pleiotrophin 0.419142
CCNK cyclin K 0.418768
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.418394
CD34 CD34 molecule 0.41727
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.416896
NBEA neurobeachin 0.413527
MSC musculin 0.404557
FECH ferrochelatase 0.403438
DUSP22 dual specificity phosphatase 22 0.399334
CD37 CD37 molecule 0.398589
HRAS Harvey rat sarcoma viral oncogene homolog 0.398216
BAG2 BCL2-associated athanogene 2 0.397098
HOXC4 homeobox C4 0.39598
AMPD2 adenosine monophosphate deaminase 2 0.391513
CCL17 chemokine (C-C motif) ligand 17 0.391141
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.384822
B3GAT1 beta-1,3-glucuronyltransferase 1 0.38111
COPB1 coatomer protein complex, subunit beta 1 0.377031
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.374438
JUN jun proto-oncogene 0.369258
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.368518
TARP TCR gamma alternate reading frame protein 0.36704
PAX2 paired box 2 0.366671
KNG1 kininogen 1 0.366301
NODAL nodal growth differentiation factor 0.363716
HBA1 hemoglobin, alpha 1 0.361133
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.360764
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.357446
PCNA proliferating cell nuclear antigen 0.355972
CDK9 cyclin-dependent kinase 9 0.35082
RNASEH2A ribonuclease H2, subunit A 0.350084
ULBP3 UL16 binding protein 3 0.347879
BRAP BRCA1 associated protein 0.346042
FGR FGR proto-oncogene, Src family tyrosine kinase 0.34384
ALB albumin 0.343106
KLB klotho beta 0.342739
PGLS 6-phosphogluconolactonase 0.341639
HBA2 hemoglobin, alpha 2 0.339806
BAX BCL2-associated X protein 0.332852
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.32701
CSF1R colony stimulating factor 1 receptor 0.32701
CLTC clathrin, heavy chain (Hc) 0.325187
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.321909
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.32009
KLF10 Kruppel-like factor 10 0.318999
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.316456
CTSS cathepsin S 0.313189
TNK2 tyrosine kinase, non-receptor, 2 0.308118
CTSB cathepsin B 0.307757
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.307395
CSNK2B casein kinase 2, beta polypeptide 0.307033
MRO maestro 0.305587
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.299812
JAK3 Janus kinase 3 0.297291
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.297291
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 0.295132
FOS FBJ murine osteosarcoma viral oncogene homolog 0.294772
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.293694
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.292257
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.287952
ARHGAP35 Rho GTPase activating protein 35 0.285802
CD2 CD2 molecule 0.285444
UCKL1 uridine-cytidine kinase 1-like 1 0.280796
BCL3 B-cell CLL/lymphoma 3 0.280082
COPA coatomer protein complex, subunit alpha 0.278654
CCNT1 cyclin T1 0.27794
LDHC lactate dehydrogenase C 0.275089
UCK1 uridine-cytidine kinase 1 0.274021
GAK cyclin G associated kinase 0.272241
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.268687
MIR197 microRNA 197 0.267977
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.26266
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.260891
CD79B CD79b molecule, immunoglobulin-associated beta 0.254183
CD38 CD38 molecule 0.252422
GLO1 glyoxalase I 0.251718
TNF tumor necrosis factor 0.250311
SHPK sedoheptulokinase 0.248203
BIN2 bridging integrator 2 0.248203
GAS6 growth arrest-specific 6 0.24715
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.246098
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.239799
KDM6B lysine (K)-specific demethylase 6B 0.23666
MCM6 minichromosome maintenance complex component 6 0.23666
TRAC T cell receptor alpha constant 0.234573
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.234225
KARS lysyl-tRNA synthetase 0.23353
XG Xg blood group 0.232836
BCR breakpoint cluster region 0.232836
GAGE1 G antigen 1 0.232489
UCK2 uridine-cytidine kinase 2 0.227297
GYPE glycophorin E (MNS blood group) 0.223509
TCEA1 transcription elongation factor A (SII), 1 0.223165
LGALS1 lectin, galactoside-binding, soluble, 1 0.220424
ERVW-1 endogenous retrovirus group W, member 1 0.220081
VAV2 vav 2 guanine nucleotide exchange factor 0.219398
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.217012
FLT4 fms-related tyrosine kinase 4 0.216332
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.216332
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.214636
HAL histidine ammonia-lyase 0.214636
POLB polymerase (DNA directed), beta 0.212271
HIST3H2BB histone cluster 3, H2bb 0.210253
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.209583
HIST2H2BF histone cluster 2, H2bf 0.208914
ULBP2 UL16 binding protein 2 0.207578
HIST1H2BH histone cluster 1, H2bh 0.20658
HIST1H2BA histone cluster 1, H2ba 0.20658
HIST1H2BD histone cluster 1, H2bd 0.20658
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.205585
LPO lactoperoxidase 0.203933
SPRY2 sprouty homolog 2 (Drosophila) 0.203933
CENPV centromere protein V 0.203604
NUP153 nucleoporin 153kDa 0.202618
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.20229
MYLK myosin light chain kinase 0.200982
IL13 interleukin 13 0.200331
RNH1 ribonuclease/angiogenin inhibitor 1 0.200006
CST3 cystatin C 0.199356
IFNA21 interferon, alpha 21 0.198709
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.19742
VAV3 vav 3 guanine nucleotide exchange factor 0.197099
ENO2 enolase 2 (gamma, neuronal) 0.196459
MIR191 microRNA 191 0.194865
ARHGAP18 Rho GTPase activating protein 18 0.194865
HIST1H2BC histone cluster 1, H2bc 0.193915
HIST1H2BF histone cluster 1, H2bf 0.193915
TRIM32 tripartite motif containing 32 0.192657
GAGE12I G antigen 12I 0.192031
PTPRD protein tyrosine phosphatase, receptor type, D 0.191719
CDA cytidine deaminase 0.190168
SSX4B synovial sarcoma, X breakpoint 4B 0.187415
SSX4 synovial sarcoma, X breakpoint 4 0.187415
AURKAIP1 aurora kinase A interacting protein 1 0.185612
ALPP alkaline phosphatase, placental 0.184128
CDC25A cell division cycle 25A 0.183835
IFNA17 interferon, alpha 17 0.181222
CHAD chondroadherin 0.180367
CDKN2A cyclin-dependent kinase inhibitor 2A 0.179239
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.178403
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 0.177851
AXL AXL receptor tyrosine kinase 0.176757
MLYCD malonyl-CoA decarboxylase 0.175411
CDC37 cell division cycle 37 0.173832
SPN sialophorin 0.173571
ZC3H12D zinc finger CCCH-type containing 12D 0.173571
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.172799
PTH parathyroid hormone 0.171785
JUNB jun B proto-oncogene 0.171036
MSN moesin 0.168854
POU2AF1 POU class 2 associating factor 1 0.167452
PARP1 poly (ADP-ribose) polymerase 1 0.167224
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.166095
STARD13 StAR-related lipid transfer (START) domain containing 13 0.165217
IGHV5-51 immunoglobulin heavy variable 5-51 0.164786
IFNA2 interferon, alpha 2 0.164786
HLA-E major histocompatibility complex, class I, E 0.164571
GLIS2 GLIS family zinc finger 2 0.164571
PATE1 prostate and testis expressed 1 0.163938
ADD2 adducin 2 (beta) 0.163111
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.162908
RAET1E retinoic acid early transcript 1E 0.162109
ARG2 arginase 2 0.161716
ALPPL2 alkaline phosphatase, placental-like 2 0.160948
ALPL alkaline phosphatase, liver/bone/kidney 0.160574
SELL selectin L 0.15948
VWF von Willebrand factor 0.143632
MNX1 motor neuron and pancreas homeobox 1 0.13757
VEGFC vascular endothelial growth factor C 0.135854
CD163 CD163 molecule 0.135029
PDPN podoplanin 0.134977
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.13496
DSP desmoplakin 0.134684
IGF1R insulin-like growth factor 1 receptor 0.129709
IGFBP3 insulin-like growth factor binding protein 3 0.126593
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 0.125893
CALCOCO2 calcium binding and coiled-coil domain 2 0.125447
MYB v-myb avian myeloblastosis viral oncogene homolog 0.125241
CSTA cystatin A (stefin A) 0.123803
CCL1 chemokine (C-C motif) ligand 1 0.123526
PANX1 pannexin 1 0.12327
IL5 interleukin 5 0.123223
BOC BOC cell adhesion associated, oncogene regulated 0.12313
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.122889
CTSD cathepsin D 0.122477
PNP purine nucleoside phosphorylase 0.121929
GSR glutathione reductase 0.121748
LIG1 ligase I, DNA, ATP-dependent 0.121594
TRIM37 tripartite motif containing 37 0.120699
BTNL2 butyrophilin-like 2 0.120645
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.120645
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.120096
RBP1 retinol binding protein 1, cellular 0.1199
FOLR2 folate receptor 2 (fetal) 0.119758
THY1 Thy-1 cell surface antigen 0.118658
TGFA transforming growth factor, alpha 0.118508
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.118448
EBF1 early B-cell factor 1 0.117685
GLS2 glutaminase 2 (liver, mitochondrial) 0.117497
USF2 upstream transcription factor 2, c-fos interacting 0.117247
FPGS folylpolyglutamate synthase 0.117247
IL10 interleukin 10 0.117091
ADA adenosine deaminase 0.117058
SACS sacsin molecular chaperone 0.1168
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.116183
IL12B interleukin 12B 0.115983
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.11575
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.115379
BTC betacellulin 0.114268
SOCS2 suppressor of cytokine signaling 2 0.113914
CSN2 casein beta 0.113661
JAG2 jagged 2 0.113041
TK1 thymidine kinase 1, soluble 0.112781
NCL nucleolin 0.112706
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.112555
GPR182 G protein-coupled receptor 182 0.112029
FRZB frizzled-related protein 0.111681
MGAT4C MGAT4 family, member C 0.111564
FOLR1 folate receptor 1 (adult) 0.110861
ANO1 anoctamin 1, calcium activated chloride channel 0.110662
FSCN1 fascin actin-bundling protein 1 0.110383
BCAR1 breast cancer anti-estrogen resistance 1 0.110064
CXCL13 chemokine (C-X-C motif) ligand 13 0.109817
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.109694
LSP1 lymphocyte-specific protein 1 0.109653
LIG4 ligase IV, DNA, ATP-dependent 0.10953
LMNB1 lamin B1 0.10953
BCL2A1 BCL2-related protein A1 0.109243
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.10912
CLEC3A C-type lectin domain family 3, member A 0.109036
CLEC2B C-type lectin domain family 2, member B 0.108446
CAT catalase 0.108361
NMU neuromedin U 0.108361
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.108277
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.108235
TRIAP1 TP53 regulated inhibitor of apoptosis 1 0.108235
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.108108
MCM2 minichromosome maintenance complex component 2 0.10785
GRAP2 GRB2-related adaptor protein 2 0.106492
MIR22 microRNA 22 0.106358
GGT1 gamma-glutamyltransferase 1 0.106136
PREB prolactin regulatory element binding 0.106091
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 0.106091
CLEC10A C-type lectin domain family 10, member A 0.105731
EPHA1 EPH receptor A1 0.104862
ITK IL2-inducible T-cell kinase 0.104583
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.104489
IFNB1 interferon, beta 1, fibroblast 0.104301
FYN FYN proto-oncogene, Src family tyrosine kinase 0.104254
TYRO3 TYRO3 protein tyrosine kinase 0.103692
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.103549
GSTA3 glutathione S-transferase alpha 3 0.103404
FRS2 fibroblast growth factor receptor substrate 2 0.103404
GSTA2 glutathione S-transferase alpha 2 0.103212
CDK4 cyclin-dependent kinase 4 0.103164
GSTA4 glutathione S-transferase alpha 4 0.103068
S100A11 S100 calcium binding protein A11 0.102972
MAGEC1 melanoma antigen family C1 0.102876
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.10278
GRB7 growth factor receptor-bound protein 7 0.102732
MBL2 mannose-binding lectin (protein C) 2, soluble 0.102443
GSTA1 glutathione S-transferase alpha 1 0.102344
PRDM2 PR domain containing 2, with ZNF domain 0.102147
CD274 CD274 molecule 0.101999
CD177 CD177 molecule 0.101999
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.101753