lymphatic endothelial cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The main type of cell found in the inside lining of lymph vessels. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004167)
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Genes

168 proteins co-occuring with the tissue lymphatic endothelial cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
PROX1 prospero homeobox 1 3.01864
VEGFC vascular endothelial growth factor C 2.99752
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.90887
PDPN podoplanin 2.77827
FLT4 fms-related tyrosine kinase 4 2.54543
CLEC1B C-type lectin domain family 1, member B 2.09097
CCL21 chemokine (C-C motif) ligand 21 1.73529
VEGFA vascular endothelial growth factor A 1.64256
FOXC2 forkhead box C2 1.58387
SOX18 SRY (sex determining region Y)-box 18 1.57552
HBA1 hemoglobin, alpha 1 1.55213
HBA2 hemoglobin, alpha 2 1.53622
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 1.49538
CCBE1 collagen and calcium binding EGF domains 1 1.37088
ITGA9 integrin, alpha 9 1.33093
CCR7 chemokine (C-C motif) receptor 7 1.3201
NRP2 neuropilin 2 1.26442
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.23227
ANGPT2 angiopoietin 2 1.22247
EMILIN1 elastin microfibril interfacer 1 1.15628
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1.13457
CDH5 cadherin 5, type 2 (vascular endothelium) 1.13147
NT5E 5'-nucleotidase, ecto (CD73) 1.04885
CD34 CD34 molecule 1.04664
KDR kinase insert domain receptor 1.01856
JAM3 junctional adhesion molecule 3 1.0024
MNX1 motor neuron and pancreas homeobox 1 0.940066
FLT1 fms-related tyrosine kinase 1 0.935341
VEGFB vascular endothelial growth factor B 0.905404
SYK spleen tyrosine kinase 0.882051
ADGRG3 adhesion G protein-coupled receptor G3 0.860521
DLL4 delta-like 4 (Drosophila) 0.833642
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.816068
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.786468
NOS3 nitric oxide synthase 3 (endothelial cell) 0.786052
ADGRL1 adhesion G protein-coupled receptor L1 0.773589
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.764468
ANGPT1 angiopoietin 1 0.76364
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.730208
VWF von Willebrand factor 0.701899
NTN4 netrin 4 0.693719
ICAM1 intercellular adhesion molecule 1 0.689226
S1PR1 sphingosine-1-phosphate receptor 1 0.677803
NOTCH1 notch 1 0.667215
FN1 fibronectin 1 0.664368
PVRL3 poliovirus receptor-related 3 0.663962
CXCL12 chemokine (C-X-C motif) ligand 12 0.656648
TMEM45A transmembrane protein 45A 0.655836
GJC2 gap junction protein, gamma 2, 47kDa 0.65543
CLEC4M C-type lectin domain family 4, member M 0.642858
GDF2 growth differentiation factor 2 0.641643
EPHB4 EPH receptor B4 0.640023
NRP1 neuropilin 1 0.633144
NRXN2 neurexin 2 0.627889
ADM adrenomedullin 0.619814
MFAP2 microfibrillar-associated protein 2 0.61699
COL4A2 collagen, type IV, alpha 2 0.606514
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.604904
GLE1 GLE1 RNA export mediator 0.604099
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.595255
NELFE negative elongation factor complex member E 0.594451
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.592845
LGALS8 lectin, galactoside-binding, soluble, 8 0.588031
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.567626
STAB1 stabilin 1 0.564833
EPN1 epsin 1 0.559652
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 0.557263
UNC5B unc-5 homolog B (C. elegans) 0.546533
PALM paralemmin 0.544152
VCAM1 vascular cell adhesion molecule 1 0.540585
EFNB2 ephrin-B2 0.537812
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.52556
EPHA1 EPH receptor A1 0.524377
GJA4 gap junction protein, alpha 4, 37kDa 0.521223
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 0.521223
F8 coagulation factor VIII, procoagulant component 0.511778
CLDN9 claudin 9 0.508242
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.50275
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 0.499615
ESAM endothelial cell adhesion molecule 0.49844
APLNR apelin receptor 0.494528
PKP4 plakophilin 4 0.484376
EPHA5 EPH receptor A5 0.483986
PDGFB platelet-derived growth factor beta polypeptide 0.482428
FDCSP follicular dendritic cell secreted protein 0.478923
CALCRL calcitonin receptor-like 0.474258
CXCL17 chemokine (C-X-C motif) ligand 17 0.470375
MLEC malectin 0.46766
FGF2 fibroblast growth factor 2 (basic) 0.458373
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.4576
TJP1 tight junction protein 1 0.451042
PF4V1 platelet factor 4 variant 1 0.449886
NEO1 neogenin 1 0.449116
CCL19 chemokine (C-C motif) ligand 19 0.448731
NOTCH4 notch 4 0.444499
EPHA7 EPH receptor A7 0.435672
EPHA3 EPH receptor A3 0.435289
CD44 CD44 molecule (Indian blood group) 0.433757
FOXC1 forkhead box C1 0.432991
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.42649
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.426109
FOXP2 forkhead box P2 0.425344
RELN reelin 0.421529
SPHK2 sphingosine kinase 2 0.420385
FGFR3 fibroblast growth factor receptor 3 0.418099
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.409351
HOXD8 homeobox D8 0.407832
MRC1 mannose receptor, C type 1 0.405935
CCL1 chemokine (C-C motif) ligand 1 0.401007
PF4 platelet factor 4 0.400628
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.3976
CCL13 chemokine (C-C motif) ligand 13 0.394197
FLT3LG fms-related tyrosine kinase 3 ligand 0.393064
PDGFC platelet derived growth factor C 0.381755
ANGPT4 angiopoietin 4 0.381379
PROM1 prominin 1 0.379123
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.378372
EFNA4 ephrin-A4 0.373493
CXCL11 chemokine (C-X-C motif) ligand 11 0.372369
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.371245
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.368624
ACVRL1 activin A receptor type II-like 1 0.366754
PGF placental growth factor 0.366381
SELE selectin E 0.36526
DAB2IP DAB2 interacting protein 0.357058
FAT4 FAT atypical cadherin 4 0.354084
RCN1 reticulocalbin 1, EF-hand calcium binding domain 0.352598
JAM2 junctional adhesion molecule 2 0.351485
SPRED1 sprouty-related, EVH1 domain containing 1 0.345188
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 0.345188
ALCAM activated leukocyte cell adhesion molecule 0.340019
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 0.336336
AOAH acyloxyacyl hydrolase (neutrophil) 0.3356
CXCL13 chemokine (C-X-C motif) ligand 13 0.335233
CD68 CD68 molecule 0.333763
MET MET proto-oncogene, receptor tyrosine kinase 0.328994
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.319498
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.319498
PPAP2B phosphatidic acid phosphatase type 2B 0.317315
TLR1 toll-like receptor 1 0.310783
MAPK3 mitogen-activated protein kinase 3 0.299242
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.298524
TSC2 tuberous sclerosis 2 0.270909
JAG1 jagged 1 0.269174
GP6 glycoprotein VI (platelet) 0.267102
YBX3 Y box binding protein 3 0.267102
GPR148 G protein-coupled receptor 148 0.261964
AQP1 aquaporin 1 (Colton blood group) 0.2559
EPHB2 EPH receptor B2 0.2559
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.254239
TP63 tumor protein p63 0.253248
GPR182 G protein-coupled receptor 182 0.250953
IL17RC interleukin 17 receptor C 0.244232
VASH1 vasohibin 1 0.243918
MCAM melanoma cell adhesion molecule 0.243605
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.241132
COL18A1 collagen, type XVIII, alpha 1 0.23961
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 0.232599
CXCL10 chemokine (C-X-C motif) ligand 10 0.230382
TAL1 T-cell acute lymphocytic leukemia 1 0.22797
CTNND1 catenin (cadherin-associated protein), delta 1 0.226667
MAP2K1 mitogen-activated protein kinase kinase 1 0.226411
NRXN1 neurexin 1 0.223177
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.216325
EPHA4 EPH receptor A4 0.216126
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.215534
WT1 Wilms tumor 1 0.215147
CD160 CD160 molecule 0.213833