luteolin-6658 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the luteolin-6658 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM28 ADAM metallopeptidase domain 28
ADGRB2 adhesion G protein-coupled receptor B2
ADPRH ADP-ribosylarginine hydrolase
AK2 adenylate kinase 2
AKR1C2 aldo-keto reductase family 1, member C2
ANGEL2 angel homolog 2 (Drosophila)
APOLD1 apolipoprotein L domain containing 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
AURKC aurora kinase C
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C8ORF44 chromosome 8 open reading frame 44
CACFD1 calcium channel flower domain containing 1
CES3 carboxylesterase 3
CFLAR CASP8 and FADD-like apoptosis regulator
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRY2 cryptochrome circadian clock 2
CSDC2 cold shock domain containing C2, RNA binding
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DSCAM Down syndrome cell adhesion molecule
DTNA dystrobrevin, alpha
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EGR1 early growth response 1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHB2 EPH receptor B2
FGF1 fibroblast growth factor 1 (acidic)
FHL5 four and a half LIM domains 5
FLJ11292
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLRX3 glutaredoxin 3
HAP1 huntingtin-associated protein 1
HCFC1 host cell factor C1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPM heterogeneous nuclear ribonucleoprotein M
HPS1 Hermansky-Pudlak syndrome 1
IFNA16 interferon, alpha 16
INSL5 insulin-like 5
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLHL22 kelch-like family member 22
KMT2A lysine (K)-specific methyltransferase 2A
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC157562 uncharacterized LOC157562
LRRC37A3 leucine rich repeat containing 37, member A3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MT3 metallothionein 3
MTMR7 myotubularin related protein 7
N4BP2L2 NEDD4 binding protein 2-like 2
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NPVF neuropeptide VF precursor
OGFR opioid growth factor receptor
OSBPL7 oxysterol binding protein-like 7
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAX4 paired box 4
PDE3B phosphodiesterase 3B, cGMP-inhibited
PGLYRP1 peptidoglycan recognition protein 1
PPP1R17 protein phosphatase 1, regulatory subunit 17
PRDM2 PR domain containing 2, with ZNF domain
PTAFR platelet-activating factor receptor
RABGAP1 RAB GTPase activating protein 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS5 regulator of G-protein signaling 5
RIMS1 regulating synaptic membrane exocytosis 1
RPL13 ribosomal protein L13
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCARB1 scavenger receptor class B, member 1
SIGLEC6 sialic acid binding Ig-like lectin 6
SLA Src-like-adaptor
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC16A4 solute carrier family 16, member 4
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SOX30 SRY (sex determining region Y)-box 30
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSTR5 somatostatin receptor 5
TAAR5 trace amine associated receptor 5
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TF transferrin
TJP3 tight junction protein 3
TM4SF4 transmembrane 4 L six family member 4
TMEM63A transmembrane protein 63A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TSPO2 translocator protein 2
TUBBP5 tubulin, beta pseudogene 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UHRF1BP1L UHRF1 binding protein 1-like
VPRBP Vpr (HIV-1) binding protein
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WSB1 WD repeat and SOCS box containing 1
YIPF4 Yip1 domain family, member 4
ZBED4 zinc finger, BED-type containing 4
ZBTB43 zinc finger and BTB domain containing 43
ZFP2 ZFP2 zinc finger protein
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF264 zinc finger protein 264
ZNF287 zinc finger protein 287
ZNF384 zinc finger protein 384
ZNF652 zinc finger protein 652
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTSL3 ADAMTS-like 3
ADRB2 adrenoceptor beta 2, surface
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX5 armadillo repeat containing, X-linked 5
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C3ORF52 chromosome 3 open reading frame 52
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCRL2 chemokine (C-C motif) receptor-like 2
CD70 CD70 molecule
CD82 CD82 molecule
CD83 CD83 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC73 cell division cycle 73
CHM choroideremia (Rab escort protein 1)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIDEC cell death-inducing DFFA-like effector c
CLIP4 CAP-GLY domain containing linker protein family, member 4
CPA4 carboxypeptidase A4
CPEB1 cytoplasmic polyadenylation element binding protein 1
CTGF connective tissue growth factor
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DNAH7 dynein, axonemal, heavy chain 7
DTX2 deltex 2, E3 ubiquitin ligase
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPHA4 EPH receptor A4
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FAM105A family with sequence similarity 105, member A
FBXO2 F-box protein 2
FCHSD2 FCH and double SH3 domains 2
GAS8 growth arrest-specific 8
GPR87 G protein-coupled receptor 87
GRAMD3 GRAM domain containing 3
HDAC7 histone deacetylase 7
HIST1H2AG histone cluster 1, H2ag
HLX H2.0-like homeobox
HOXB9 homeobox B9
HOXC6 homeobox C6
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INPP1 inositol polyphosphate-1-phosphatase
MAGEF1 melanoma antigen family F1
MANSC1 MANSC domain containing 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MTA2 metastasis associated 1 family, member 2
MYO19 myosin XIX
NAP1L3 nucleosome assembly protein 1-like 3
NDP Norrie disease (pseudoglioma)
NINJ1 ninjurin 1
NME5 NME/NM23 family member 5
NPY1R neuropeptide Y receptor Y1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAQR3 progestin and adipoQ receptor family member III
PARP3 poly (ADP-ribose) polymerase family, member 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLCD1 phospholipase C, delta 1
PLK2 polo-like kinase 2
POMT2 protein-O-mannosyltransferase 2
PPT2 palmitoyl-protein thioesterase 2
RAB17 RAB17, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RFTN1 raftlin, lipid raft linker 1
RHOBTB1 Rho-related BTB domain containing 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
SAMD9 sterile alpha motif domain containing 9
SEPP1 selenoprotein P, plasma, 1
SETBP1 SET binding protein 1
SFMBT1 Scm-like with four mbt domains 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SNHG20 small nucleolar RNA host gene 20
SPHK1 sphingosine kinase 1
STARD3 StAR-related lipid transfer (START) domain containing 3
SYT1 synaptotagmin I
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TIAM1 T-cell lymphoma invasion and metastasis 1
TIGD6 tigger transposable element derived 6
TMEM121 transmembrane protein 121
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
WDR25 WD repeat domain 25
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB10 zinc finger and BTB domain containing 10
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFHX3 zinc finger homeobox 3
ZNF222 zinc finger protein 222
ZNF248 zinc finger protein 248
ZNF480 zinc finger protein 480