luteolin-3041 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the luteolin-3041 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACSM1 acyl-CoA synthetase medium-chain family member 1
AIM1L absent in melanoma 1-like
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
AMACR alpha-methylacyl-CoA racemase
AOC2 amine oxidase, copper containing 2 (retina-specific)
AOC3 amine oxidase, copper containing 3
APOLD1 apolipoprotein L domain containing 1
ATP13A2 ATPase type 13A2
AVIL advillin
BAGE B melanoma antigen
BTBD18 BTB (POZ) domain containing 18
CARD10 caspase recruitment domain family, member 10
CCL20 chemokine (C-C motif) ligand 20
CCL27 chemokine (C-C motif) ligand 27
CDH10 cadherin 10, type 2 (T2-cadherin)
CEL carboxyl ester lipase
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CRABP2 cellular retinoic acid binding protein 2
CREM cAMP responsive element modulator
CTNND1 catenin (cadherin-associated protein), delta 1
DSG3 desmoglein 3
DUSP4 dual specificity phosphatase 4
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGR3 early growth response 3
ESR1 estrogen receptor 1
ETV7 ets variant 7
FLOT1 flotillin 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GABARAPL1 GABA(A) receptor-associated protein like 1
GCM1 glial cells missing homolog 1 (Drosophila)
HBEGF heparin-binding EGF-like growth factor
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IER3 immediate early response 3
IL24 interleukin 24
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCTD17 potassium channel tetramerization domain containing 17
KIAA1211L KIAA1211-like
KLHL3 kelch-like family member 3
KRCC1 lysine-rich coiled-coil 1
LOC157562 uncharacterized LOC157562
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MSH4 mutS homolog 4
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
N4BP2L2 NEDD4 binding protein 2-like 2
NEB nebulin
NPR3 natriuretic peptide receptor 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NT5E 5'-nucleotidase, ecto (CD73)
NUP88 nucleoporin 88kDa
NXPE4 neurexophilin and PC-esterase domain family, member 4
OMG oligodendrocyte myelin glycoprotein
OVGP1 oviductal glycoprotein 1, 120kDa
PAQR6 progestin and adipoQ receptor family member VI
PCBP4 poly(rC) binding protein 4
PDE4DIP phosphodiesterase 4D interacting protein
PHF7 PHD finger protein 7
PRDM2 PR domain containing 2, with ZNF domain
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
QPCTL glutaminyl-peptide cyclotransferase-like
RARB retinoic acid receptor, beta
RBBP9 retinoblastoma binding protein 9
RFPL3S RFPL3 antisense
RGS5 regulator of G-protein signaling 5
RGS6 regulator of G-protein signaling 6
RNF39 ring finger protein 39
RNF6 ring finger protein (C3H2C3 type) 6
RPL31 ribosomal protein L31
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SARM1 sterile alpha and TIR motif containing 1
SCG5 secretogranin V
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAI1 snail family zinc finger 1
SRR serine racemase
ST20 suppressor of tumorigenicity 20
TAC3 tachykinin 3
TACR1 tachykinin receptor 1
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAS2R4 taste receptor, type 2, member 4
TF transferrin
TG thyroglobulin
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TNF tumor necrosis factor
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TPH1 tryptophan hydroxylase 1
ZBTB1 zinc finger and BTB domain containing 1
ZNF137P zinc finger protein 137, pseudogene
ZNF177 zinc finger protein 177
ZNF276 zinc finger protein 276
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABHD3 abhydrolase domain containing 3
ADGRA3 adhesion G protein-coupled receptor A3
ADRB2 adrenoceptor beta 2, surface
ADSS adenylosuccinate synthase
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
BAG2 BCL2-associated athanogene 2
BBS7 Bardet-Biedl syndrome 7
C11ORF21 chromosome 11 open reading frame 21
C17ORF70 chromosome 17 open reading frame 70
C9ORF91 chromosome 9 open reading frame 91
CA2 carbonic anhydrase II
CBR1 carbonyl reductase 1
CCR2 chemokine (C-C motif) receptor 2
CD9 CD9 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPJ centromere protein J
CEP83 centrosomal protein 83kDa
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHST10 carbohydrate sulfotransferase 10
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLTCL1 clathrin, heavy chain-like 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUTC cutC copper transporter
CYSLTR1 cysteinyl leukotriene receptor 1
DCPS decapping enzyme, scavenger
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEPTOR DEP domain containing MTOR-interacting protein
DIXDC1 DIX domain containing 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPY19L2P2 DPY19L2 pseudogene 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ENAH enabled homolog (Drosophila)
FAM63A family with sequence similarity 63, member A
FGL2 fibrinogen-like 2
FUCA1 fucosidase, alpha-L- 1, tissue
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GFI1 growth factor independent 1 transcription repressor
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPR63 G protein-coupled receptor 63
GPR85 G protein-coupled receptor 85
HCAR3 hydroxycarboxylic acid receptor 3
HDAC9 histone deacetylase 9
HIST1H2AG histone cluster 1, H2ag
HK2 hexokinase 2
HSPA1L heat shock 70kDa protein 1-like
HSPA4L heat shock 70kDa protein 4-like
ICAM2 intercellular adhesion molecule 2
IFI35 interferon-induced protein 35
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRF8 interferon regulatory factor 8
ISOC1 isochorismatase domain containing 1
JADE3 jade family PHD finger 3
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
LINC00597 long intergenic non-protein coding RNA 597
LMNB1 lamin B1
LPAR6 lysophosphatidic acid receptor 6
LXN latexin
MCRS1 microspherule protein 1
METTL1 methyltransferase like 1
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NCF1C neutrophil cytosolic factor 1C pseudogene
NCS1 neuronal calcium sensor 1
NFE2 nuclear factor, erythroid 2
NOD1 nucleotide-binding oligomerization domain containing 1
NTSR1 neurotensin receptor 1 (high affinity)
OCEL1 occludin/ELL domain containing 1
PAQR3 progestin and adipoQ receptor family member III
PDZD7 PDZ domain containing 7
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLS1 plastin 1
RHOBTB1 Rho-related BTB domain containing 1
RPE ribulose-5-phosphate-3-epimerase
SERINC5 serine incorporator 5
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFMBT1 Scm-like with four mbt domains 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLITRK5 SLIT and NTRK-like family, member 5
SMYD3 SET and MYND domain containing 3
SPC25 SPC25, NDC80 kinetochore complex component
TEC tec protein tyrosine kinase
TGIF2 TGFB-induced factor homeobox 2
THBS4 thrombospondin 4
TLR2 toll-like receptor 2
TRABD TraB domain containing
TRHDE thyrotropin-releasing hormone degrading enzyme
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC27 tetratricopeptide repeat domain 27
WT1 Wilms tumor 1
XAF1 XIAP associated factor 1
ZHX2 zinc fingers and homeoboxes 2
ZNF248 zinc finger protein 248
ZNF345 zinc finger protein 345