lupus erythematosus Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:8857
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Genes

136 genes associated with the disease lupus erythematosus in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
MSH5 mutS homolog 5 2.58122
CFB complement factor B 2.56926
C6ORF10 chromosome 6 open reading frame 10 2.52164
STAT4 signal transducer and activator of transcription 4 2.46446
HLA-DRA major histocompatibility complex, class II, DR alpha 2.42563
TNXB tenascin XB 2.245
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.22046
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.10732
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.07237
TNPO3 transportin 3 1.92462
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.91853
GPR19 G protein-coupled receptor 19 1.89896
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.8787
CD80 CD80 molecule 1.85801
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 1.83309
BLK BLK proto-oncogene, Src family tyrosine kinase 1.77893
UHRF1BP1 UHRF1 binding protein 1 1.69467
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.65612
WDFY4 WDFY family member 4 1.64762
LOC100506023 uncharacterized LOC100506023 1.64556
C6ORF106 chromosome 6 open reading frame 106 1.64204
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 1.62029
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.62029
XKR6 XK, Kell blood group complex subunit-related family, member 6 1.61349
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.60875
BANK1 B-cell scaffold protein with ankyrin repeats 1 1.59746
PXK PX domain containing serine/threonine kinase 1.59609
ARID5B AT rich interactive domain 5B (MRF1-like) 1.59609
KIAA0319L KIAA0319-like 1.57556
PHRF1 PHD and ring finger domains 1 1.54533
FAM167A-AS1 FAM167A antisense RNA 1 1.53704
LRRC18 leucine rich repeat containing 18 1.52677
TNIP1 TNFAIP3 interacting protein 1 1.48714
LYN LYN proto-oncogene, Src family tyrosine kinase 1.45183
IRF5 interferon regulatory factor 5 1.45183
AFF1 AF4/FMR2 family, member 1 1.43537
C10ORF11 chromosome 10 open reading frame 11 1.42713
ELF1 E74-like factor 1 (ets domain transcription factor) 1.42467
NOTCH4 notch 4 1.42068
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 1.41984
CREBL2 cAMP responsive element binding protein-like 2 1.39396
JAZF1 JAZF zinc finger 1 1.39396
HIP1 huntingtin interacting protein 1 1.39396
MUC22 mucin 22 1.37988
CLDN10 claudin 10 1.37414
C2 complement component 2 1.35588
APOM apolipoprotein M 1.35208
IL12RB2 interleukin 12 receptor, beta 2 1.32469
STK19 serine/threonine kinase 19 1.3189
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 1.31332
SCUBE1 signal peptide, CUB domain, EGF-like 1 1.30905
ATG5 autophagy related 5 1.30472
ICA1 islet cell autoantigen 1, 69kDa 1.29132
SAMD9L sterile alpha motif domain containing 9-like 1.28906
CD247 CD247 molecule 1.27903
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 1.26953
CLEC16A C-type lectin domain family 16, member A 1.24194
ZSCAN26 zinc finger and SCAN domain containing 26 1.24032
AVEN apoptosis, caspase activation inhibitor 1.23898
ZNF112 zinc finger protein 112 1.23766
MUC21 mucin 21, cell surface associated 1.23496
LAMC2 laminin, gamma 2 1.23034
LINC00305 long intergenic non-protein coding RNA 305 1.22576
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.22228
GRB2 growth factor receptor-bound protein 2 1.20583
CLCA1 chloride channel accessory 1 1.19031
BANP BTG3 associated nuclear protein 1.18285
MACROD2 MACRO domain containing 2 1.18117
DLG2 discs, large homolog 2 (Drosophila) 1.16856
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.16438
CNTNAP2 contactin associated protein-like 2 1.16089
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.16089
BBS5 Bardet-Biedl syndrome 5 1.158
LEF1 lymphoid enhancer-binding factor 1 1.14463
GRK4 G protein-coupled receptor kinase 4 1.14463
YDJC YdjC homolog (bacterial) 1.14065
AUH AU RNA binding protein/enoyl-CoA hydratase 1.13008
UPK1B uroplakin 1B 1.11914
DPH2 DPH2 homolog (S. cerevisiae) 1.11647
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 1.11485
STPG2 sperm-tail PG-rich repeat containing 2 1.11384
TTC7A tetratricopeptide repeat domain 7A 1.11086
NTNG2 netrin G2 1.10764
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 1.10764
RHPN2 rhophilin, Rho GTPase binding protein 2 1.10088
TMTC1 transmembrane and tetratricopeptide repeat containing 1 1.09959
PDE4B phosphodiesterase 4B, cAMP-specific 1.09284
ANKRD44 ankyrin repeat domain 44 1.06777
ANXA6 annexin A6 1.05943
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.05003
TCF19 transcription factor 19 1.03399
LY6G6C lymphocyte antigen 6 complex, locus G6C 1.03199
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 1.02476
ZSCAN31 zinc finger and SCAN domain containing 31 1.0216
ZNRD1 zinc ribbon domain containing 1 1.02071
IKZF3 IKAROS family zinc finger 3 (Aiolos) 1.00407
OR4A15 olfactory receptor, family 4, subfamily A, member 15 1.00407
SEZ6L2 seizure related 6 homolog (mouse)-like 2 1.00407
MOB3B MOB kinase activator 3B 1.00407
NEGR1 neuronal growth regulator 1 1.00407
BTN2A1 butyrophilin, subfamily 2, member A1 0.992121
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.986376
TMC2 transmembrane channel-like 2 0.986376
HSPA1B heat shock 70kDa protein 1B 0.984103
PGBD1 piggyBac transposable element derived 1 0.983462
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.976827
HCG9 HLA complex group 9 (non-protein coding) 0.943097
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.940135
SRCIN1 SRC kinase signaling inhibitor 1 0.938237
PRRC2A proline-rich coiled-coil 2A 0.928472
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.928472
EHMT2 euchromatic histone-lysine N-methyltransferase 2 0.908515
PLXNA4 plexin A4 0.904255
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.903565
DPCR1 diffuse panbronchiolitis critical region 1 0.901524
RNF39 ring finger protein 39 0.896938
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.891974
PUM1 pumilio RNA-binding family member 1 0.871229
PVT1 Pvt1 oncogene (non-protein coding) 0.845188
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.832379
TSPAN11 tetraspanin 11 0.823542
VWA7 von Willebrand factor A domain containing 7 0.815684
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.808055
HIC2 hypermethylated in cancer 2 0.758489
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.69773
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.684944
LPAR1 lysophosphatidic acid receptor 1 0.650844
AVL9 AVL9 homolog (S. cerevisiase) 0.644215
LRRC20 leucine rich repeat containing 20 0.629714
AKAP2 A kinase (PRKA) anchor protein 2 0.624931
VSIG2 V-set and immunoglobulin domain containing 2 0.611686
TMEM39A transmembrane protein 39A 0.599097
IP6K3 inositol hexakisphosphate kinase 3 0.594024
RSBN1 round spermatid basic protein 1 0.591098
SOX5 SRY (sex determining region Y)-box 5 0.582834
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 0.535547