lupus erythematosus Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

84 genes associated with the disease lupus erythematosus in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CFB complement factor B 2.21059
TNXB tenascin XB 1.71485
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.50071
STAT4 signal transducer and activator of transcription 4 1.43901
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.42422
IRF5 interferon regulatory factor 5 1.29434
GPR19 G protein-coupled receptor 19 1.21385
TET3 tet methylcytosine dioxygenase 3 1.19506
TREH trehalase (brush-border membrane glycoprotein) 1.17894
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.17894
CD80 CD80 molecule 1.13588
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.09588
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 1.09588
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.965481
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.894262
UHRF1BP1 UHRF1 binding protein 1 0.894262
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.872896
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.842276
LRRC18 leucine rich repeat containing 18 0.830123
DRAM1 DNA-damage regulated autophagy modulator 1 0.820928
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.790827
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 0.790827
TNPO3 transportin 3 0.790827
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.774217
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.774217
ARID5B AT rich interactive domain 5B (MRF1-like) 0.752991
BLK BLK proto-oncogene, Src family tyrosine kinase 0.724323
PTTG1 pituitary tumor-transforming 1 0.724323
PHRF1 PHD and ring finger domains 1 0.682635
FAM167A-AS1 FAM167A antisense RNA 1 0.670996
MICB MHC class I polypeptide-related sequence B 0.661797
LOC392787 filamin C pseudogene 0.63207
TNIP1 TNFAIP3 interacting protein 1 0.602429
LYN LYN proto-oncogene, Src family tyrosine kinase 0.561725
PXK PX domain containing serine/threonine kinase 0.544585
AFF1 AF4/FMR2 family, member 1 0.537125
ELF1 E74-like factor 1 (ets domain transcription factor) 0.52461
HIP1 huntingtin interacting protein 1 0.486425
CREBL2 cAMP responsive element binding protein-like 2 0.486425
PRDM1 PR domain containing 1, with ZNF domain 0.486425
PRR14 proline rich 14 0.464771
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.403461
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 0.403461
LINC00208 long intergenic non-protein coding RNA 208 0.403461
ATG5 autophagy related 5 0.403461
SCUBE1 signal peptide, CUB domain, EGF-like 1 0.403461
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.368757
ICA1 islet cell autoantigen 1, 69kDa 0.368757
PDHX pyruvate dehydrogenase complex, component X 0.368757
ZNF689 zinc finger protein 689 0.345945
JAZF1 JAZF zinc finger 1 0.327313
CLEC16A C-type lectin domain family 16, member A 0.311576
LAMC2 laminin, gamma 2 0.297866
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.285417
ATF6B activating transcription factor 6 beta 0.264872
DDA1 DET1 and DDB1 associated 1 0.256228
COL25A1 collagen, type XXV, alpha 1 0.256228
LEF1 lymphoid enhancer-binding factor 1 0.197766
NOTCH4 notch 4 0.15771
WDFY4 WDFY family member 4 0.15771
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.15771
IL10 interleukin 10 0.15771
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.15771
NTNG2 netrin G2 0.15771
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 0.15771
GHR growth hormone receptor 0.126165
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.126165
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 0.126165
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.100789
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.100789
OSBPL8 oxysterol binding protein-like 8 0.100789
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.100789
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 0.080593
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.080593
LYST lysosomal trafficking regulator 0.080593
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.064973
SCN10A sodium channel, voltage gated, type X alpha subunit 0.064973
NEGR1 neuronal growth regulator 1 0.064973
OR4A15 olfactory receptor, family 4, subfamily A, member 15 0.064973
TMC2 transmembrane channel-like 2 0.052255
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.052255
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.052255
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.043246
NRXN1 neurexin 1 0.043246