lung squamous cell carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A non-small cell lung carcinoma that has_material_basis_in the squamous cell. (Human Disease Ontology, DOID_3907)
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Genes

195 genes co-occuring with the disease lung squamous cell carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SLC35F2 solute carrier family 35, member F2 1.33938
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 1.15581
CCDC37 coiled-coil domain containing 37 1.12361
RPP40 ribonuclease P/MRP 40kDa subunit 1.11435
GOSR1 golgi SNAP receptor complex member 1 1.07362
OVCA2 ovarian tumor suppressor candidate 2 1.02144
NAPSA napsin A aspartic peptidase 1.01596
DENND2D DENN/MADD domain containing 2D 0.97086
RPS11 ribosomal protein S11 0.97002
HYAL3 hyaluronoglucosaminidase 3 0.947852
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.906498
TPX2 TPX2, microtubule-associated 0.894589
GRAMD4 GRAM domain containing 4 0.892538
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 0.886799
PTBP3 polypyrimidine tract binding protein 3 0.882701
XAGE1B X antigen family, member 1B 0.881062
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.874509
PTHLH parathyroid hormone-like hormone 0.856497
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.853221
MPZL2 myelin protein zero-like 2 0.836427
TACC3 transforming, acidic coiled-coil containing protein 3 0.799513
LGALS8 lectin, galactoside-binding, soluble, 8 0.790902
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.784345
KIF15 kinesin family member 15 0.76921
NFE2L2 nuclear factor, erythroid 2-like 2 0.758601
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.756971
RPS9 ribosomal protein S9 0.756564
PDPN podoplanin 0.742329
PEBP4 phosphatidylethanolamine-binding protein 4 0.737865
ASCC3 activating signal cointegrator 1 complex subunit 3 0.720058
PRDM5 PR domain containing 5 0.71925
PEBP1 phosphatidylethanolamine binding protein 1 0.718039
SOX2 SRY (sex determining region Y)-box 2 0.716021
IPO8 importin 8 0.716021
KIFC1 kinesin family member C1 0.710378
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.707559
TP53 tumor protein p53 0.70233
EYA2 EYA transcriptional coactivator and phosphatase 2 0.698313
SARNP SAP domain containing ribonucleoprotein 0.692296
RAP2B RAP2B, member of RAS oncogene family 0.676706
LMO3 LIM domain only 3 (rhombotin-like 2) 0.676308
SSBP2 single-stranded DNA binding protein 2 0.673518
DDR2 discoidin domain receptor tyrosine kinase 2 0.672324
S100A2 S100 calcium binding protein A2 0.670333
SOCS6 suppressor of cytokine signaling 6 0.666358
PRKCI protein kinase C, iota 0.666358
CLEC1B C-type lectin domain family 1, member B 0.661594
LYPD3 LY6/PLAUR domain containing 3 0.654463
EIF4A2 eukaryotic translation initiation factor 4A2 0.652089
FGFR1 fibroblast growth factor receptor 1 0.633956
BAG4 BCL2-associated athanogene 4 0.633169
CCDC130 coiled-coil domain containing 130 0.628457
ANLN anillin, actin binding protein 0.624927
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.617877
MADD MAP-kinase activating death domain 0.616703
KEAP1 kelch-like ECH-associated protein 1 0.616312
FBXO11 F-box protein 11 0.610838
CERS2 ceramide synthase 2 0.610057
NKX2-1 NK2 homeobox 1 0.588612
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.584719
CALU calumenin 0.565277
CCAR2 cell cycle and apoptosis regulator 2 0.553627
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.551298
GAS7 growth arrest-specific 7 0.545093
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.536957
SIAH2 siah E3 ubiquitin protein ligase 2 0.529994
CD109 CD109 molecule 0.529608
GPC3 glypican 3 0.528835
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.526518
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.526132
TAGLN2 transgelin 2 0.52536
CDO1 cysteine dioxygenase type 1 0.524588
FGFR3 fibroblast growth factor receptor 3 0.522273
XAGE1E X antigen family, member 1E 0.51919
EGFR epidermal growth factor receptor 0.518805
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.517265
BIRC6 baculoviral IAP repeat containing 6 0.509959
CYTL1 cytokine-like 1 0.507657
PLEKHN1 pleckstrin homology domain containing, family N member 1 0.503441
MIR93 microRNA 93 0.500379
RPLP0 ribosomal protein, large, P0 0.495793
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.491978
RAE1 ribonucleic acid export 1 0.487407
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.485505
FGFR2 fibroblast growth factor receptor 2 0.484744
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.481325
CLEC3A C-type lectin domain family 3, member A 0.481325
RAD18 RAD18 E3 ubiquitin protein ligase 0.477909
CLEC2B C-type lectin domain family 2, member B 0.476393
SQLE squalene epoxidase 0.471468
IQGAP1 IQ motif containing GTPase activating protein 1 0.469197
FSCN3 fascin actin-bundling protein 3, testicular 0.462016
RPS14 ribosomal protein S14 0.459373
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.456355
CLEC10A C-type lectin domain family 10, member A 0.452962
KRT19 keratin 19, type I 0.43753
FSCN2 fascin actin-bundling protein 2, retinal 0.435275
RAN RAN, member RAS oncogene family 0.434899
TFDP3 transcription factor Dp family, member 3 0.433397
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.425139
ALYREF Aly/REF export factor 0.424765
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.413527
GSTM1 glutathione S-transferase mu 1 0.412405
ACSL1 acyl-CoA synthetase long-chain family member 1 0.409414
KRT5 keratin 5, type II 0.406425
FGF19 fibroblast growth factor 19 0.401572
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.393746
HDGF hepatoma-derived growth factor 0.391141
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.388538
ADAM28 ADAM metallopeptidase domain 28 0.387423
OGG1 8-oxoguanine DNA glycosylase 0.386308
BPGM 2,3-bisphosphoglycerate mutase 0.383708
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.377402
GMNN geminin, DNA replication inhibitor 0.375179
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.373328
DSC2 desmocollin 2 0.367779
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.365932
ENO1 enolase 1, (alpha) 0.365932
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.364824
ALDOA aldolase A, fructose-bisphosphate 0.361502
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.360026
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.359289
TSPYL5 TSPY-like 5 0.353395
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.348981
ACP1 acid phosphatase 1, soluble 0.345675
MIR210 microRNA 210 0.341272
FSCN1 fascin actin-bundling protein 1 0.340173
ALK anaplastic lymphoma receptor tyrosine kinase 0.339806
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.336876
FOXO3 forkhead box O3 0.33651
CA9 carbonic anhydrase IX 0.325552
LOXL2 lysyl oxidase-like 2 0.325187
CLDN1 claudin 1 0.321545
KRAS Kirsten rat sarcoma viral oncogene homolog 0.320817
PTK7 protein tyrosine kinase 7 (inactive) 0.318635
KIF5B kinesin family member 5B 0.317545
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.307395
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.304503
SAR1A secretion associated, Ras related GTPase 1A 0.298731
CUL3 cullin 3 0.298371
BAD BCL2-associated agonist of cell death 0.291539
STK11 serine/threonine kinase 11 0.285086
KMT2B lysine (K)-specific methyltransferase 2B 0.284728
FGF9 fibroblast growth factor 9 0.284013
HHAT hedgehog acyltransferase 0.279367
MARCKS myristoylated alanine-rich protein kinase C substrate 0.278654
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.278654
PIGR polymeric immunoglobulin receptor 0.275445
DSC3 desmocollin 3 0.273664
FGF3 fibroblast growth factor 3 0.268687
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.268332
HRAS Harvey rat sarcoma viral oncogene homolog 0.268332
DUSP6 dual specificity phosphatase 6 0.266913
SOX4 SRY (sex determining region Y)-box 4 0.265849
SNAI1 snail family zinc finger 1 0.265494
HIC1 hypermethylated in cancer 1 0.256299
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.25207
CNN1 calponin 1, basic, smooth muscle 0.247852
TSPYL4 TSPY-like 4 0.238752
PRDX6 peroxiredoxin 6 0.238403
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.233878
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.23353
LRP6 low density lipoprotein receptor-related protein 6 0.224196
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.223853
MIR31 microRNA 31 0.219398
SETD1A SET domain containing 1A 0.214297
PLAU plasminogen activator, urokinase 0.213621
CTNND1 catenin (cadherin-associated protein), delta 1 0.212945
S100A7 S100 calcium binding protein A7 0.207245
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.204263
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit 0.203275
PTEN phosphatase and tensin homolog 0.199356
FOXA1 forkhead box A1 0.197742
KRT7 keratin 7, type II 0.197742
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.190786
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.182957
ERCC2 excision repair cross-complementation group 2 0.182086
CD2 CD2 molecule 0.18151
PCNA proliferating cell nuclear antigen 0.17952
NT5C 5', 3'-nucleotidase, cytosolic 0.177301
PGM1 phosphoglucomutase 1 0.174617
PHB prohibitin 0.173571
HMOX2 heme oxygenase 2 0.173057
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.171036
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.170054
GLO1 glyoxalase I 0.167915
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.166768
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.164786
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.164359
MAPK3 mitogen-activated protein kinase 3 0.163729
PARK2 parkin RBR E3 ubiquitin protein ligase 0.162306
CTTN cortactin 0.162109
AREG amphiregulin 0.161523
JUP junction plakoglobin 0.15948
TXN thioredoxin 0.158778