lung small cell carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells. (Human Disease Ontology, DOID_5409)
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Genes

182 genes co-occuring with the disease lung small cell carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ENO2 enolase 2 (gamma, neuronal) 1.9108
GRP gastrin-releasing peptide 1.69587
SYP synaptophysin 1.56222
CHGA chromogranin A 1.45748
NCAM1 neural cell adhesion molecule 1 1.19057
AVP arginine vasopressin 1.13247
POMC proopiomelanocortin 1.08537
TP53 tumor protein p53 1.02777
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 1.02735
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.996549
NKX2-1 NK2 homeobox 1 0.988957
RCVRN recoverin 0.890898
CNN1 calponin 1, basic, smooth muscle 0.883111
TOP1 topoisomerase (DNA) I 0.863865
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.855268
SST somatostatin 0.81059
B3GAT1 beta-1,3-glucuronyltransferase 1 0.767167
CLCN3 chloride channel, voltage-sensitive 3 0.763902
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.739894
MS4A8 membrane-spanning 4-domains, subfamily A, member 8 0.728143
PPIE peptidylprolyl isomerase E (cyclophilin E) 0.721673
NPS neuropeptide S 0.717232
SEZ6L seizure related 6 homolog (mouse)-like 0.715618
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.696306
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.682693
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 0.674713
PALD1 phosphatase domain containing, paladin 1 0.665563
TAGLN transgelin 0.660404
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 0.650508
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.606543
ERCC1 excision repair cross-complementation group 1 0.60264
NMB neuromedin B 0.595233
MIRLET7A3 microRNA let-7a-3 0.576161
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.575383
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 0.570329
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.566054
CDKN2A cyclin-dependent kinase inhibitor 2A 0.564112
ERBB2 erb-b2 receptor tyrosine kinase 2 0.561004
CALCA calcitonin-related polypeptide alpha 0.552075
HN1 hematological and neurological expressed 1 0.545481
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.545481
KRT20 keratin 20, type I 0.545093
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.526132
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.526132
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.513417
HRAS Harvey rat sarcoma viral oncogene homolog 0.512264
GAST gastrin 0.509192
LHX6 LIM homeobox 6 0.49274
KRT7 keratin 7, type II 0.478289
RALBP1 ralA binding protein 1 0.47753
ITGB5 integrin, beta 5 0.475634
TAC1 tachykinin, precursor 1 0.469954
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.460506
ASCL1 achaete-scute family bHLH transcription factor 1 0.455224
NMBR neuromedin B receptor 0.447687
PCBP1 poly(rC) binding protein 1 0.447687
KRT19 keratin 19, type I 0.440538
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.440162
BEST3 bestrophin 3 0.438658
CD1E CD1e molecule 0.433397
NQO1 NAD(P)H dehydrogenase, quinone 1 0.42739
MIR217 microRNA 217 0.42664
CD44 CD44 molecule (Indian blood group) 0.42289
DPYSL5 dihydropyrimidinase-like 5 0.42139
LHX2 LIM homeobox 2 0.415398
VIP vasoactive intestinal peptide 0.411657
MIR98 microRNA 98 0.411283
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.404931
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 0.399334
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.398962
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.398216
UCKL1 uridine-cytidine kinase 1-like 1 0.396725
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.396353
PRAMEF6 PRAME family member 6 0.392257
UCK1 uridine-cytidine kinase 1 0.390025
BEST2 bestrophin 2 0.387423
MIR197 microRNA 197 0.383337
NTS neurotensin 0.382594
BRS3 bombesin-like receptor 3 0.380368
SCGN secretagogin, EF-hand calcium binding protein 0.373698
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.370737
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.370368
FOSL1 FOS-like antigen 1 0.366301
OAT ornithine aminotransferase 0.35892
RALB v-ral simian leukemia viral oncogene homolog B 0.353763
GLE1 GLE1 RNA export mediator 0.345308
BCL2 B-cell CLL/lymphoma 2 0.341639
UCK2 uridine-cytidine kinase 2 0.340539
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.337975
KRAS Kirsten rat sarcoma viral oncogene homolog 0.337242
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.337242
TMPRSS13 transmembrane protease, serine 13 0.33651
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.32774
LCK LCK proto-oncogene, Src family tyrosine kinase 0.326281
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.326281
FBXO42 F-box protein 42 0.325552
LCN1 lipocalin 1 0.323002
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.323002
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.318635
MIRLET7D microRNA let-7d 0.315729
ALPPL2 alkaline phosphatase, placental-like 2 0.311377
ALPP alkaline phosphatase, placental 0.311014
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.310652
ALPL alkaline phosphatase, liver/bone/kidney 0.31029
MFGE8 milk fat globule-EGF factor 8 protein 0.309566
SKI SKI proto-oncogene 0.308118
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.307395
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.306672
KNG1 kininogen 1 0.295132
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.295132
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.294413
POU3F2 POU class 3 homeobox 2 0.292257
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.291898
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.279724
SNRPA small nuclear ribonucleoprotein polypeptide A 0.27794
OPN3 opsin 3 0.276514
PAX2 paired box 2 0.271886
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.263368
ZMYND10 zinc finger, MYND-type containing 10 0.262306
RARB retinoic acid receptor, beta 0.262306
MET MET proto-oncogene, receptor tyrosine kinase 0.261952
RAB1A RAB1A, member RAS oncogene family 0.260538
SSTR2 somatostatin receptor 2 0.258417
MST1 macrophage stimulating 1 0.252422
MBD4 methyl-CpG binding domain protein 4 0.250311
PTEN phosphatase and tensin homolog 0.249257
KRT5 keratin 5, type II 0.243295
CSF3 colony stimulating factor 3 (granulocyte) 0.241196
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.240497
DNAH8 dynein, axonemal, heavy chain 8 0.240148
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.239101
TAPBP TAP binding protein (tapasin) 0.237357
BAX BCL2-associated X protein 0.231795
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.228333
EDN2 endothelin 2 0.226607
NAPSA napsin A aspartic peptidase 0.226262
AR androgen receptor 0.225917
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.225573
MIR137 microRNA 137 0.224884
SFTPA1 surfactant protein A1 0.218374
SOX1 SRY (sex determining region Y)-box 1 0.212271
MVP major vault protein 0.211597
MIR93 microRNA 93 0.209248
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.20229
EXO1 exonuclease 1 0.201635
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.198709
HOXA5 homeobox A5 0.195501
CDR2L cerebellar degeneration-related protein 2-like 0.191408
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.186811
MIRLET7C microRNA let-7c 0.183248
NUTM1 NUT midline carcinoma, family member 1 0.182957
GFAP glial fibrillary acidic protein 0.17952
LXN latexin 0.17896
ALK anaplastic lymphoma receptor tyrosine kinase 0.178403
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.177301
PAX5 paired box 5 0.177029
SSTR3 somatostatin receptor 3 0.172544
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.172038
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.171785
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.169091
KRT4 keratin 4, type II 0.167682
PCSK9 proprotein convertase subtilisin/kexin type 9 0.166544
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 0.166095
IGF1 insulin-like growth factor 1 (somatomedin C) 0.164786
IGFBP7 insulin-like growth factor binding protein 7 0.163317
PAX9 paired box 9 0.162707
EGFR epidermal growth factor receptor 0.161912
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.161523
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.161331
KLK3 kallikrein-related peptidase 3 0.160574
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.158778
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.157602
CALD1 caldesmon 1 0.144686
MYOG myogenin (myogenic factor 4) 0.144142
CXCR2 chemokine (C-X-C motif) receptor 2 0.142145
VIM vimentin 0.141962
ATP11A ATPase, class VI, type 11A 0.140523
PTGDR prostaglandin D2 receptor (DP) 0.140362
CKB creatine kinase, brain 0.139925
SV2B synaptic vesicle glycoprotein 2B 0.139681
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.138373
CKM creatine kinase, muscle 0.137096