lung inflammation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001861
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Genes

132 gene mutations causing the lung inflammation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACKR3 atypical chemokine receptor 3
AHR aryl hydrocarbon receptor
AIRE autoimmune regulator
AMPD3 adenosine monophosphate deaminase 3
APOE apolipoprotein E
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ATF3 activating transcription factor 3
BCL6 B-cell CLL/lymphoma 6
BIN3 bridging integrator 3
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
BPIFA1 BPI fold containing family A, member 1
BSG basigin (Ok blood group)
CARD11 caspase recruitment domain family, member 11
CAV1 caveolin 1, caveolae protein, 22kDa
CCR1 chemokine (C-C motif) receptor 1
CD1D CD1d molecule
CD44 CD44 molecule (Indian blood group)
CD72 CD72 molecule
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD2 chromodomain helicase DNA binding protein 2
CISH cytokine inducible SH2-containing protein
CLCA1 chloride channel accessory 1
CLEC4D C-type lectin domain family 4, member D
CLEC7A C-type lectin domain family 7, member A
CMKLR1 chemerin chemokine-like receptor 1
COL1A1 collagen, type I, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CRLF2 cytokine receptor-like factor 2
CROCC ciliary rootlet coiled-coil, rootletin
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCR3 chemokine (C-X-C motif) receptor 3
CYBA cytochrome b-245, alpha polypeptide
DKC1 dyskeratosis congenita 1, dyskerin
DTX1 deltex 1, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
EFS embryonal Fyn-associated substrate
FASLG Fas ligand (TNF superfamily, member 6)
FBN1 fibrillin 1
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FFAR2 free fatty acid receptor 2
FOXO3 forkhead box O3
FOXP3 forkhead box P3
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPC3 glypican 3
GPR132 G protein-coupled receptor 132
GPRC5A G protein-coupled receptor, class C, group 5, member A
HCK HCK proto-oncogene, Src family tyrosine kinase
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
HPS1 Hermansky-Pudlak syndrome 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL2 interleukin 2
IL22 interleukin 22
IL25 interleukin 25
IL33 interleukin 33
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
JAM3 junctional adhesion molecule 3
LAT linker for activation of T cells
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LIPA lipase A, lysosomal acid, cholesterol esterase
LPAR2 lysophosphatidic acid receptor 2
LTA lymphotoxin alpha
LTB4R leukotriene B4 receptor
LYST lysosomal trafficking regulator
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MARK2 MAP/microtubule affinity-regulating kinase 2
MIR155 microRNA 155
MIR223 microRNA 223
MMP10 matrix metallopeptidase 10
MMP9 matrix metallopeptidase 9
NCKAP1L NCK-associated protein 1-like
NDFIP1 Nedd4 family interacting protein 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NPAS3 neuronal PAS domain protein 3
PRDX3 peroxiredoxin 3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
RAG2 recombination activating gene 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS3 regulator of G-protein signaling 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
SCARA5 scavenger receptor class A, member 5
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SFTPA1 surfactant protein A1
SFTPD surfactant protein D
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT1 sirtuin 1
SMAD9 SMAD family member 9
SPTA1 spectrin, alpha, erythrocytic 1
TANK TRAF family member-associated NFKB activator
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TK1 thymidine kinase 1, soluble
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TNF tumor necrosis factor
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TP53 tumor protein p53
TRAF4 TNF receptor-associated factor 4
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
USP25 ubiquitin specific peptidase 25
VIP vasoactive intestinal peptide
WWTR1 WW domain containing transcription regulator 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa