lung development Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. (Gene Ontology, GO_0030324)
External Link http://amigo.geneontology.org/amigo/term/GO:0030324
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Genes

81 genes participating in the lung development biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AARD alanine and arginine rich domain containing protein
ACVR2B activin A receptor, type IIB
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ARG1 arginase 1
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
BAG6 BCL2-associated athanogene 6
BMPR1A bone morphogenetic protein receptor, type IA
C11ORF73 chromosome 11 open reading frame 73
CCDC39 coiled-coil domain containing 39
CCDC40 coiled-coil domain containing 40
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CRH corticotropin releasing hormone
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CUX1 cut-like homeobox 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DHCR7 7-dehydrocholesterol reductase
DICER1 dicer 1, ribonuclease type III
DNAAF1 dynein, axonemal, assembly factor 1
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF1 fibroblast growth factor 1 (acidic)
FGF18 fibroblast growth factor 18
FGFR2 fibroblast growth factor receptor 2
FOXF1 forkhead box F1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GPC3 glypican 3
HEG1 heart development protein with EGF-like domains 1
HES1 hes family bHLH transcription factor 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPB11 heat shock protein family B (small), member 11
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JMJD6 jumonji domain containing 6
LAMA5 laminin, alpha 5
LHX3 LIM homeobox 3
LIPA lipase A, lysosomal acid, cholesterol esterase
LOX lysyl oxidase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NKX2-1 NK2 homeobox 1
NKX2-8 NK2 homeobox 8
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPHP3 nephronophthisis 3 (adolescent)
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPN podoplanin
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PROX1 prospero homeobox 1
RAB3A RAB3A, member RAS oncogene family
RBP4 retinol binding protein 4, plasma
SHH sonic hedgehog
SIM2 single-minded family bHLH transcription factor 2
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SMAD2 SMAD family member 2
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SREBF1 sterol regulatory element binding transcription factor 1
STRA6 stimulated by retinoic acid 6
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX4 T-box 4
TBX5 T-box 5
TIMELESS timeless circadian clock
TSHZ3 teashirt zinc finger homeobox 3
VEGFA vascular endothelial growth factor A
WNT2 wingless-type MMTV integration site family member 2
WNT5A wingless-type MMTV integration site family, member 5A
WNT7B wingless-type MMTV integration site family, member 7B
ZFPM2 zinc finger protein, FOG family member 2
ZIC3 Zic family member 3