lung adenocarcinoma Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A non-small cell lung carcinoma that derives_from epithelial cells of glandular origin. (Human Disease Ontology, DOID_3910)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:3910
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Genes

167 genes associated with the disease lung adenocarcinoma in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.56622
HYKK hydroxylysine kinase 2.51379
TERT telomerase reverse transcriptase 2.43168
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 1.95165
IREB2 iron-responsive element binding protein 2 1.91328
TP63 tumor protein p63 1.88858
APOM apolipoprotein M 1.65612
CLPTM1L CLPTM1-like 1.58809
BPTF bromodomain PHD finger transcription factor 1.5865
MSH5 mutS homolog 5 1.56634
C6ORF10 chromosome 6 open reading frame 10 1.55951
C2 complement component 2 1.55233
BTNL2 butyrophilin-like 2 1.54533
ZNRD1 zinc ribbon domain containing 1 1.5265
HCG18 HLA complex group 18 (non-protein coding) 1.52489
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.52105
CFB complement factor B 1.52037
STK19 serine/threonine kinase 19 1.51976
PPP1R18 protein phosphatase 1, regulatory subunit 18 1.51648
RNF39 ring finger protein 39 1.48409
HCG9 HLA complex group 9 (non-protein coding) 1.46859
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.46859
TCF19 transcription factor 19 1.44871
TNXB tenascin XB 1.39148
DPCR1 diffuse panbronchiolitis critical region 1 1.35834
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 1.33649
NOTCH4 notch 4 1.3308
ZNRD1-AS1 ZNRD1 antisense RNA 1 1.25437
LDB2 LIM domain binding 2 1.23898
TRIM31 tripartite motif containing 31 1.23484
LOC100129636 uncharacterized LOC100129636 1.20832
FAM13A family with sequence similarity 13, member A 1.19534
ZNRF3 zinc and ring finger 3 1.18459
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 1.184
PRRC2A proline-rich coiled-coil 2A 1.17295
C6ORF15 chromosome 6 open reading frame 15 1.1676
GPANK1 G patch domain and ankyrin repeats 1 1.15841
SEC63 SEC63 homolog (S. cerevisiae) 1.15563
OR12D3 olfactory receptor, family 12, subfamily D, member 3 1.1395
FLOT1 flotillin 1 1.13689
VLDLR very low density lipoprotein receptor 1.13453
M6PR mannose-6-phosphate receptor (cation dependent) 1.13411
PHC1 polyhomeotic homolog 1 (Drosophila) 1.13248
VARS2 valyl-tRNA synthetase 2, mitochondrial 1.12333
EML1 echinoderm microtubule associated protein like 1 1.12051
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.11234
TLE2 transducin-like enhancer of split 2 1.10419
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.10219
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 1.09553
PDCD6 programmed cell death 6 1.09167
UBR1 ubiquitin protein ligase E3 component n-recognin 1 1.09022
LOC100507424 uncharacterized LOC100507424 1.07193
FKBP11 FK506 binding protein 11, 19 kDa 1.06483
MEOX2 mesenchyme homeobox 2 1.04846
LRRC16A leucine rich repeat containing 16A 1.02499
PGBD1 piggyBac transposable element derived 1 1.02138
DPF3 D4, zinc and double PHD fingers, family 3 1.01514
ZFP57 ZFP57 zinc finger protein 0.998208
C10ORF11 chromosome 10 open reading frame 11 0.974612
PRR16 proline rich 16 0.973307
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.963371
EGFL8 EGF-like-domain, multiple 8 0.948266
C5 complement component 5 0.943097
PSORS1C1 psoriasis susceptibility 1 candidate 1 0.93638
SH3PXD2B SH3 and PX domains 2B 0.93456
TGM5 transglutaminase 5 0.90636
PTPRD protein tyrosine phosphatase, receptor type, D 0.902879
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.902879
CNTN5 contactin 5 0.896938
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.887807
CHODL chondrolectin 0.869084
HPSE2 heparanase 2 (inactive) 0.860976
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 0.859982
CAMKMT calmodulin-lysine N-methyltransferase 0.853791
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 0.848917
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 0.848443
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B 0.845188
MYH9 myosin, heavy chain 9, non-muscle 0.844278
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 0.84116
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 0.837718
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.833181
SRD5A3 steroid 5 alpha-reductase 3 0.831981
TMCO6 transmembrane and coiled-coil domains 6 0.82519
PRC1 protein regulator of cytokinesis 1 0.82192
EHMT2 euchromatic histone-lysine N-methyltransferase 2 0.820721
AMICA1 adhesion molecule, interacts with CXADR antigen 1 0.820721
CA10 carbonic anhydrase X 0.819144
SUN5 Sad1 and UNC84 domain containing 5 0.816443
SGMS1 sphingomyelin synthase 1 0.812707
CAPN12 calpain 12 0.811614
ZBTB16 zinc finger and BTB domain containing 16 0.810892
MEMO1 mediator of cell motility 1 0.809109
MORF4L1 mortality factor 4 like 1 0.808756
LINGO2 leucine rich repeat and Ig domain containing 2 0.808055
PCDH17 protocadherin 17 0.804621
COL19A1 collagen, type XIX, alpha 1 0.802948
LOC100506985 uncharacterized LOC100506985 0.798453
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.79668
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.794936
TP53BP1 tumor protein p53 binding protein 1 0.785994
GLDN gliomedin 0.78442
JADE2 jade family PHD finger 2 0.782562
EBF3 early B-cell factor 3 0.778355
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.777475
WNK1 WNK lysine deficient protein kinase 1 0.776314
NUCB2 nucleobindin 2 0.775452
AGBL4 ATP/GTP binding protein-like 4 0.775452
ULK2 unc-51 like autophagy activating kinase 2 0.770703
PPARA peroxisome proliferator-activated receptor alpha 0.769887
PSD3 pleckstrin and Sec7 domain containing 3 0.769617
TENM2 teneurin transmembrane protein 2 0.768778
SETBP1 SET binding protein 1 0.766993
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 0.766699
LOC644662 0.764084
MRPL54 mitochondrial ribosomal protein L54 0.762657
LOC285692 uncharacterized LOC285692 0.760137
SGCZ sarcoglycan, zeta 0.757946
ACTN4 actinin, alpha 4 0.755798
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.751374
NELFE negative elongation factor complex member E 0.750612
EIF3K eukaryotic translation initiation factor 3, subunit K 0.747128
RYR1 ryanodine receptor 1 (skeletal) 0.746154
ZNF229 zinc finger protein 229 0.74567
LBH limb bud and heart development 0.741877
AMPD3 adenosine monophosphate deaminase 3 0.736658
IP6K2 inositol hexakisphosphate kinase 2 0.736436
SFTPB surfactant protein B 0.7253
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.724417
GPR158 G protein-coupled receptor 158 0.722026
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.719267
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.716781
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.715965
HCG27 HLA complex group 27 (non-protein coding) 0.714954
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.713553
LRRC4C leucine rich repeat containing 4C 0.712368
CNTN4 contactin 4 0.708508
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.708508
KMT2E lysine (K)-specific methyltransferase 2E 0.70663
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.704784
SORBS3 sorbin and SH3 domain containing 3 0.70333
MCHR2 melanin-concentrating hormone receptor 2 0.70297
BSN bassoon presynaptic cytomatrix protein 0.702253
REM1 RAS (RAD and GEM)-like GTP-binding 1 0.70172
EFR3A EFR3 homolog A (S. cerevisiae) 0.700315
RNF165 ring finger protein 165 0.69066
FMN1 formin 1 0.690501
MIR3135B microRNA 3135b 0.68924
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.688615
ROR1 receptor tyrosine kinase-like orphan receptor 1 0.684944
PCDHA9 protocadherin alpha 9 0.683601
CSMD1 CUB and Sushi multiple domains 1 0.683452
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.682862
LINC00473 long intergenic non-protein coding RNA 473 0.682275
SCAF11 SR-related CTD-associated factor 11 0.679818
TGFB2 transforming growth factor, beta 2 0.679107
SECISBP2L SECIS binding protein 2-like 0.677002
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.675898
ZNF287 zinc finger protein 287 0.674263
SH2D4B SH2 domain containing 4B 0.671074
PDGFB platelet-derived growth factor beta polypeptide 0.670682
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.669646
KLHL31 kelch-like family member 31 0.611686
SPACA1 sperm acrosome associated 1 0.59964
SPRED1 sprouty-related, EVH1 domain containing 1 0.541061
WWOX WW domain containing oxidoreductase 0.541061
NELL1 NEL-like 1 (chicken) 0.51817
TSPAN33 tetraspanin 33 0.510061