loss of dopaminergic neurons Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description loss of the neurons that utilize dopamine as a neurotransmitter, commonly due to an apoptotic event (Mammalian Phenotype Ontology, MP_0003244)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003244
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Genes

8 gene mutations causing the loss of dopaminergic neurons phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
GFRA1 GDNF family receptor alpha 1
GRN granulin
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
NR4A2 nuclear receptor subfamily 4, group A, member 2
OTX2 orthodenticle homeobox 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PITX3 paired-like homeodomain 3
TGFB3 transforming growth factor, beta 3