lorglumide-6456 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the lorglumide-6456 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADORA1 adenosine A1 receptor
AMELY amelogenin, Y-linked
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APLNR apelin receptor
ASTN2 astrotactin 2
ATN1 atrophin 1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BCL2 B-cell CLL/lymphoma 2
C11ORF63 chromosome 11 open reading frame 63
C15ORF39 chromosome 15 open reading frame 39
CALCA calcitonin-related polypeptide alpha
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CCDC64 coiled-coil domain containing 64
CCR4 chemokine (C-C motif) receptor 4
CFAP74 cilia and flagella associated protein 74
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
COL19A1 collagen, type XIX, alpha 1
COMMD4 COMM domain containing 4
CPNE7 copine VII
CSNK1G1 casein kinase 1, gamma 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
DCN decorin
DICER1 dicer 1, ribonuclease type III
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DPT dermatopontin
DPY19L1P1 DPY19L1 pseudogene 1
DUOX2 dual oxidase 2
EGFR epidermal growth factor receptor
EGR3 early growth response 3
ELOVL2 ELOVL fatty acid elongase 2
FABP3 fatty acid binding protein 3, muscle and heart
FAXDC2 fatty acid hydroxylase domain containing 2
FKBP10 FK506 binding protein 10, 65 kDa
FRMD4A FERM domain containing 4A
GLB1L galactosidase, beta 1-like
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GP5 glycoprotein V (platelet)
GRIP2 glutamate receptor interacting protein 2
GUCA2A guanylate cyclase activator 2A (guanylin)
HIPK2 homeodomain interacting protein kinase 2
HOXD3 homeobox D3
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFNA17 interferon, alpha 17
IL1RN interleukin 1 receptor antagonist
JAK2 Janus kinase 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF5A kinesin family member 5A
KRT31 keratin 31, type I
LOC392555 melanoma antigen family C2 pseudogene
MMP3 matrix metallopeptidase 3
MTA1 metastasis associated 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL3 NIPA-like domain containing 3
NT5M 5',3'-nucleotidase, mitochondrial
ONECUT2 one cut homeobox 2
OPCML opioid binding protein/cell adhesion molecule-like
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4DIP phosphodiesterase 4D interacting protein
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PICK1 protein interacting with PRKCA 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCL2 phospholipase C-like 2
POPDC3 popeye domain containing 3
PPY pancreatic polypeptide
PQLC2 PQ loop repeat containing 2
PRKCQ protein kinase C, theta
PTAFR platelet-activating factor receptor
RUNX1 runt-related transcription factor 1
SCEL sciellin
SCN10A sodium channel, voltage gated, type X alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SH2D1A SH2 domain containing 1A
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SMAD6 SMAD family member 6
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRRT serrate, RNA effector molecule
TBX6 T-box 6
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TET3 tet methylcytosine dioxygenase 3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFB2 transforming growth factor, beta 2
TK2 thymidine kinase 2, mitochondrial
TMEM80 transmembrane protein 80
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TTC38 tetratricopeptide repeat domain 38
TTLL4 tubulin tyrosine ligase-like family member 4
TULP1 tubby like protein 1
WDFY3 WD repeat and FYVE domain containing 3
ZNF532 zinc finger protein 532

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ASPN asporin
ATAD5 ATPase family, AAA domain containing 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAGE B melanoma antigen
BCAS1 breast carcinoma amplified sequence 1
BTF3P12 basic transcription factor 3 pseudogene 12
CDKL3 cyclin-dependent kinase-like 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CIR1 corepressor interacting with RBPJ, 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGB3 cyclic nucleotide gated channel beta 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CXXC4 CXXC finger protein 4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DENND4A DENN/MADD domain containing 4A
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSE dermatan sulfate epimerase
DYSF dysferlin
EDAR ectodysplasin A receptor
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA4 EPH receptor A4
ERCC6 excision repair cross-complementation group 6
FGF23 fibroblast growth factor 23
GBP2 guanylate binding protein 2, interferon-inducible
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH3 G patch domain containing 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HINFP histone H4 transcription factor
HIST1H2AK histone cluster 1, H2ak
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
KLC2 kinesin light chain 2
LHX1 LIM homeobox 1
LIME1 Lck interacting transmembrane adaptor 1
LOXL3 lysyl oxidase-like 3
LYRM9 LYR motif containing 9
MARC1 mitochondrial amidoxime reducing component 1
MCC mutated in colorectal cancers
METTL4 methyltransferase like 4
MICALL2 MICAL-like 2
MYO1E myosin IE
NCAM2 neural cell adhesion molecule 2
NECAP2 NECAP endocytosis associated 2
NFE2L3 nuclear factor, erythroid 2-like 3
NLRX1 NLR family member X1
NT5C 5', 3'-nucleotidase, cytosolic
NUPL2 nucleoporin like 2
OGFRL1 opioid growth factor receptor-like 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PARPBP PARP1 binding protein
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PNPLA6 patatin-like phospholipase domain containing 6
PRDM14 PR domain containing 14
PROS1 protein S (alpha)
REEP4 receptor accessory protein 4
RPL23AP32 ribosomal protein L23a pseudogene 32
SECTM1 secreted and transmembrane 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFRP5 secreted frizzled-related protein 5
SKA1 spindle and kinetochore associated complex subunit 1
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLIT2 slit homolog 2 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBL3 transducin (beta)-like 3
TMEM254 transmembrane protein 254
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPST1 tyrosylprotein sulfotransferase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN1 tetraspanin 1
TTC4 tetratricopeptide repeat domain 4
VAV1 vav 1 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VLDLR very low density lipoprotein receptor
WDR76 WD repeat domain 76
WLS wntless Wnt ligand secretion mediator
XYLT2 xylosyltransferase II
ZMAT5 zinc finger, matrin-type 5
ZNF204P zinc finger protein 204, pseudogene
ZNF324 zinc finger protein 324
ZNF442 zinc finger protein 442
ZNF492 zinc finger protein 492
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675