Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the lobeline-6258 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AKAP9 | A kinase (PRKA) anchor protein 9 |
ALOXE3 | arachidonate lipoxygenase 3 |
ARMC4 | armadillo repeat containing 4 |
ATG3 | autophagy related 3 |
BMP6 | bone morphogenetic protein 6 |
BSDC1 | BSD domain containing 1 |
BTD | biotinidase |
CAMKMT | calmodulin-lysine N-methyltransferase |
CASP9 | caspase 9, apoptosis-related cysteine peptidase |
CBX8 | chromobox homolog 8 |
CCDC71 | coiled-coil domain containing 71 |
CCDC93 | coiled-coil domain containing 93 |
CLIC2 | chloride intracellular channel 2 |
CLK1 | CDC-like kinase 1 |
CUL4B | cullin 4B |
CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
CYTH1 | cytohesin 1 |
DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
DOK4 | docking protein 4 |
DRD2 | dopamine receptor D2 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
EFCAB11 | EF-hand calcium binding domain 11 |
EGFR | epidermal growth factor receptor |
ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
FAM13C | family with sequence similarity 13, member C |
FAM169A | family with sequence similarity 169, member A |
FBXL6 | F-box and leucine-rich repeat protein 6 |
FCF1 | FCF1 rRNA-processing protein |
FCMR | Fc fragment of IgM receptor |
FGF2 | fibroblast growth factor 2 (basic) |
FKBP8 | FK506 binding protein 8, 38kDa |
FRK | fyn-related Src family tyrosine kinase |
FZD10 | frizzled class receptor 10 |
GOLIM4 | golgi integral membrane protein 4 |
GPR1 | G protein-coupled receptor 1 |
HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
HFE | hemochromatosis |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
HSPA1L | heat shock 70kDa protein 1-like |
IL1RL1 | interleukin 1 receptor-like 1 |
JUNB | jun B proto-oncogene |
KAT8 | K(lysine) acetyltransferase 8 |
KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
KLF6 | Kruppel-like factor 6 |
LDB1 | LIM domain binding 1 |
LIN7A | lin-7 homolog A (C. elegans) |
MAP2K5 | mitogen-activated protein kinase kinase 5 |
MAPK13 | mitogen-activated protein kinase 13 |
MET | MET proto-oncogene, receptor tyrosine kinase |
METTL7A | methyltransferase like 7A |
MID1 | midline 1 |
MID2 | midline 2 |
MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
MTMR1 | myotubularin related protein 1 |
MXD3 | MAX dimerization protein 3 |
MYOF | myoferlin |
NAAA | N-acylethanolamine acid amidase |
NADK | NAD kinase |
NF2 | neurofibromin 2 (merlin) |
NIPAL2 | NIPA-like domain containing 2 |
NMT2 | N-myristoyltransferase 2 |
NPEPPS | aminopeptidase puromycin sensitive |
PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
PAX5 | paired box 5 |
PGAP1 | post-GPI attachment to proteins 1 |
PHC1 | polyhomeotic homolog 1 (Drosophila) |
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
PTRF | polymerase I and transcript release factor |
QKI | QKI, KH domain containing, RNA binding |
RIN2 | Ras and Rab interactor 2 |
RNF19B | ring finger protein 19B |
ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
RPLP2 | ribosomal protein, large, P2 |
SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
SFXN3 | sideroflexin 3 |
SIX1 | SIX homeobox 1 |
SOWAHC | sosondowah ankyrin repeat domain family member C |
SP1 | Sp1 transcription factor |
SPPL2B | signal peptide peptidase like 2B |
STRN | striatin, calmodulin binding protein |
SUGP1 | SURP and G patch domain containing 1 |
SVIL | supervillin |
SYN2 | synapsin II |
TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
USB1 | U6 snRNA biogenesis 1 |
USP34 | ubiquitin specific peptidase 34 |
UTRN | utrophin |
VPS37C | vacuolar protein sorting 37 homolog C (S. cerevisiae) |
WDR25 | WD repeat domain 25 |
WDR62 | WD repeat domain 62 |
ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
Symbol | Name |
---|---|
ABHD14A | abhydrolase domain containing 14A |
ACTL8 | actin-like 8 |
ADGRE5 | adhesion G protein-coupled receptor E5 |
AEN | apoptosis enhancing nuclease |
AMDHD2 | amidohydrolase domain containing 2 |
APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
BBC3 | BCL2 binding component 3 |
BMP15 | bone morphogenetic protein 15 |
BTF3P12 | basic transcription factor 3 pseudogene 12 |
CCDC25 | coiled-coil domain containing 25 |
CEP72 | centrosomal protein 72kDa |
CERK | ceramide kinase |
CGREF1 | cell growth regulator with EF-hand domain 1 |
CNPY3 | canopy FGF signaling regulator 3 |
CNR2 | cannabinoid receptor 2 (macrophage) |
COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
DUSP8 | dual specificity phosphatase 8 |
EFCAB2 | EF-hand calcium binding domain 2 |
ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
ETHE1 | ethylmalonic encephalopathy 1 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FBXO46 | F-box protein 46 |
FLRT3 | fibronectin leucine rich transmembrane protein 3 |
GID4 | GID complex subunit 4 |
GLI3 | GLI family zinc finger 3 |
GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
GTPBP2 | GTP binding protein 2 |
HIRA | histone cell cycle regulator |
HIST1H2AM | histone cluster 1, H2am |
HMHA1 | histocompatibility (minor) HA-1 |
IFT81 | intraflagellar transport 81 |
IGSF1 | immunoglobulin superfamily, member 1 |
IL15RA | interleukin 15 receptor, alpha |
IL2 | interleukin 2 |
INO80D | INO80 complex subunit D |
IRF6 | interferon regulatory factor 6 |
KDM5C | lysine (K)-specific demethylase 5C |
KLHL21 | kelch-like family member 21 |
KPTN | kaptin (actin binding protein) |
LAMA3 | laminin, alpha 3 |
LNPEP | leucyl/cystinyl aminopeptidase |
LRP3 | low density lipoprotein receptor-related protein 3 |
LYRM9 | LYR motif containing 9 |
MED15 | mediator complex subunit 15 |
MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
MRPL52 | mitochondrial ribosomal protein L52 |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
MYL5 | myosin, light chain 5, regulatory |
NPIPB15 | nuclear pore complex interacting protein family, member B15 |
NUP62CL | nucleoporin 62kDa C-terminal like |
PDE12 | phosphodiesterase 12 |
PGP | phosphoglycolate phosphatase |
PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
PMCH | pro-melanin-concentrating hormone |
POMT2 | protein-O-mannosyltransferase 2 |
PQLC1 | PQ loop repeat containing 1 |
PRPH | peripherin |
PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
PTPRU | protein tyrosine phosphatase, receptor type, U |
RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
RCOR3 | REST corepressor 3 |
RECQL4 | RecQ protein-like 4 |
RNF39 | ring finger protein 39 |
S100A4 | S100 calcium binding protein A4 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SDF2 | stromal cell-derived factor 2 |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
SLC12A9 | solute carrier family 12, member 9 |
SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
SLC22A18 | solute carrier family 22, member 18 |
SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
SMA4 | glucuronidase, beta pseudogene |
SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
SND1-IT1 | SND1 intronic transcript 1 |
SPIDR | scaffolding protein involved in DNA repair |
STARD5 | StAR-related lipid transfer (START) domain containing 5 |
TAGLN | transgelin |
TAOK1 | TAO kinase 1 |
TPST1 | tyrosylprotein sulfotransferase 1 |
TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
USP20 | ubiquitin specific peptidase 20 |
VASH1 | vasohibin 1 |
VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
VEGFC | vascular endothelial growth factor C |
VN1R1 | vomeronasal 1 receptor 1 |
WLS | wntless Wnt ligand secretion mediator |
XAB2 | XPA binding protein 2 |
XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
ZNF219 | zinc finger protein 219 |
ZNF280D | zinc finger protein 280D |
ZNF442 | zinc finger protein 442 |
ZNF552 | zinc finger protein 552 |
ZNF571 | zinc finger protein 571 |