liver degeneration Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description deterioration of the liver due to injury or disease, often accompanied by loss of function (Mammalian Phenotype Ontology, MP_0003103)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003103
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Genes

22 gene mutations causing the liver degeneration phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DPH1 diphthamide biosynthesis 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ERCC1 excision repair cross-complementation group 1
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GNMT glycine N-methyltransferase
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL6 interleukin 6
LRP1 low density lipoprotein receptor-related protein 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
PEX7 peroxisomal biogenesis factor 7
PHYH phytanoyl-CoA 2-hydroxylase
PROC protein C (inactivator of coagulation factors Va and VIIIa)
RB1CC1 RB1-inducible coiled-coil 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SOCS1 suppressor of cytokine signaling 1
SPTA1 spectrin, alpha, erythrocytic 1
SRSF10 serine/arginine-rich splicing factor 10
TBK1 TANK-binding kinase 1
TXNIP thioredoxin interacting protein