liver/biliary system phenotype Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005370
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Genes

870 gene mutations causing the liver/biliary system phenotype phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ABHD5 abhydrolase domain containing 5
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACADL acyl-CoA dehydrogenase, long chain
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACADVL acyl-CoA dehydrogenase, very long chain
ACAN aggrecan
ACOT11 acyl-CoA thioesterase 11
ACOT13 acyl-CoA thioesterase 13
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACTA1 actin, alpha 1, skeletal muscle
ACVR2B activin A receptor, type IIB
ACVRL1 activin A receptor type II-like 1
ADA adenosine deaminase
ADAR adenosine deaminase, RNA-specific
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADD2 adducin 2 (beta)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADK adenosine kinase
ADM adrenomedullin
AEBP1 AE binding protein 1
AGA aspartylglucosaminidase
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AGRP agouti related neuropeptide
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
AIP aryl hydrocarbon receptor interacting protein
AIRE autoimmune regulator
AKAP12 A kinase (PRKA) anchor protein 12
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALMS1 Alstrom syndrome protein 1
AMACR alpha-methylacyl-CoA racemase
ANGPTL3 angiopoietin-like 3
ANK1 ankyrin 1, erythrocytic
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOC1 apolipoprotein C-I
APOE apolipoprotein E
APOF apolipoprotein F
ARF6 ADP-ribosylation factor 6
ARG1 arginase 1
ARHGAP1 Rho GTPase activating protein 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARID4A AT rich interactive domain 4A (RBP1-like)
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL3 ADP-ribosylation factor-like 3
ARRDC3 arrestin domain containing 3
ARSG arylsulfatase G
AS3MT arsenite methyltransferase
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASGR1 asialoglycoprotein receptor 1
ASIP agouti signaling protein
ASXL1 additional sex combs like transcriptional regulator 1
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATG5 autophagy related 5
ATOX1 antioxidant 1 copper chaperone
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATR ATR serine/threonine kinase
ATXN2 ataxin 2
AZIN1 antizyme inhibitor 1
B9D1 B9 protein domain 1
BAG1 BCL2-associated athanogene
BAG3 BCL2-associated athanogene 3
BBS2 Bardet-Biedl syndrome 2
BBS4 Bardet-Biedl syndrome 4
BCAR1 breast cancer anti-estrogen resistance 1
BCKDK branched chain ketoacid dehydrogenase kinase
BCL6 B-cell CLL/lymphoma 6
BCO1 beta-carotene oxygenase 1
BCO2 beta-carotene oxygenase 2
BCR breakpoint cluster region
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BHLHA15 basic helix-loop-helix family, member a15
BHMT betaine--homocysteine S-methyltransferase
BICC1 BicC family RNA binding protein 1
BIN3 bridging integrator 3
BIRC6 baculoviral IAP repeat containing 6
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
BRD1 bromodomain containing 1
BRD2 bromodomain containing 2
BRD4 bromodomain containing 4
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BSG basigin (Ok blood group)
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C1ORF127 chromosome 1 open reading frame 127
C3 complement component 3
C3AR1 complement component 3a receptor 1
C4A complement component 4A (Rodgers blood group)
C5AR2 complement component 5a receptor 2
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBFB core-binding factor, beta subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBS cystathionine-beta-synthase
CCAR2 cell cycle and apoptosis regulator 2
CCBE1 collagen and calcium binding EGF domains 1
CCDC39 coiled-coil domain containing 39
CCKAR cholecystokinin A receptor
CCKBR cholecystokinin B receptor
CCL13 chemokine (C-C motif) ligand 13
CCNDBP1 cyclin D-type binding-protein 1
CCNG1 cyclin G1
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD1D CD1d molecule
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CDK2 cyclin-dependent kinase 2
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPE centromere protein E, 312kDa
CES1 carboxylesterase 1
CFC1 cripto, FRL-1, cryptic family 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD2 chromodomain helicase DNA binding protein 2
CHKA choline kinase alpha
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
CHRM4 cholinergic receptor, muscarinic 4
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CHTOP chromatin target of PRMT1
CHUK conserved helix-loop-helix ubiquitous kinase
CIAPIN1 cytokine induced apoptosis inhibitor 1
CIDEC cell death-inducing DFFA-like effector c
CLCA2 chloride channel accessory 2
CLCN3 chloride channel, voltage-sensitive 3
CLEC4G C-type lectin domain family 4, member G
CLN3 ceroid-lipofuscinosis, neuronal 3
CLOCK clock circadian regulator
CNOT3 CCR4-NOT transcription complex, subunit 3
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
CP ceruloplasmin (ferroxidase)
CPT1C carnitine palmitoyltransferase 1C
CRBN cereblon
CREM cAMP responsive element modulator
CRH corticotropin releasing hormone
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRTC2 CREB regulated transcription coactivator 2
CRTC3 CREB regulated transcription coactivator 3
CSF1 colony stimulating factor 1 (macrophage)
CSHL1 chorionic somatomammotropin hormone-like 1
CSPG4 chondroitin sulfate proteoglycan 4
CTBS chitobiase, di-N-acetyl-
CTH cystathionine gamma-lyase
CTHRC1 collagen triple helix repeat containing 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSA cathepsin A
CTSG cathepsin G
CTSV cathepsin V
CUL3 cullin 3
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCR2 chemokine (C-X-C motif) receptor 2
CYBRD1 cytochrome b reductase 1
CYGB cytoglobin
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1
CYS1 cystin 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DDIT3 DNA-damage-inducible transcript 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEDD death effector domain containing
DEGS1 delta(4)-desaturase, sphingolipid 1
DFNB31 deafness, autosomal recessive 31
DGAT1 diacylglycerol O-acyltransferase 1
DHCR7 7-dehydrocholesterol reductase
DICER1 dicer 1, ribonuclease type III
DLK1 delta-like 1 homolog (Drosophila)
DNAAF3 dynein, axonemal, assembly factor 3
DNAH11 dynein, axonemal, heavy chain 11
DNAH5 dynein, axonemal, heavy chain 5
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DNM1L dynamin 1-like
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPH1 diphthamide biosynthesis 1
DRD2 dopamine receptor D2
DTX1 deltex 1, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
E2F2 E2F transcription factor 2
EBF1 early B-cell factor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFS embryonal Fyn-associated substrate
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF6 eukaryotic translation initiation factor 6
ELOVL5 ELOVL fatty acid elongase 5
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPAS1 endothelial PAS domain protein 1
EPB41 erythrocyte membrane protein band 4.1
EPHA3 EPH receptor A3
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPM2AIP1 EPM2A (laforin) interacting protein 1
EPO erythropoietin
EPOR erythropoietin receptor
ERCC1 excision repair cross-complementation group 1
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR2 estrogen receptor 2 (ER beta)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F5 coagulation factor V (proaccelerin, labile factor)
FABP1 fatty acid binding protein 1, liver
FABP2 fatty acid binding protein 2, intestinal
FABP3 fatty acid binding protein 3, muscle and heart
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP6 fatty acid binding protein 6, ileal
FADS2 fatty acid desaturase 2
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAIM Fas apoptotic inhibitory molecule
FAM132B family with sequence similarity 132, member B
FAM20B family with sequence similarity 20, member B
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXL5 F-box and leucine-rich repeat protein 5
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FECH ferrochelatase
FEN1 flap structure-specific endonuclease 1
FES FES proto-oncogene, tyrosine kinase
FFAR1 free fatty acid receptor 1
FFAR4 free fatty acid receptor 4
FGA fibrinogen alpha chain
FGF21 fibroblast growth factor 21
FGFR2 fibroblast growth factor receptor 2
FGL1 fibrinogen-like 1
FKBP1A FK506 binding protein 1A, 12kDa
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLNA filamin A, alpha
FLT4 fms-related tyrosine kinase 4
FNIP1 folliculin interacting protein 1
FOXA2 forkhead box A2
FOXM1 forkhead box M1
FOXN1 forkhead box N1
FOXO1 forkhead box O1
FOXP3 forkhead box P3
FREM1 FRAS1 related extracellular matrix 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUZ fuzzy planar cell polarity protein
G0S2 G0/G1 switch 2
G6PC glucose-6-phosphatase, catalytic subunit
GAB1 GRB2-associated binding protein 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GATA6 GATA binding protein 6
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBA glucosidase, beta, acid
GBE1 glucan (1,4-alpha-), branching enzyme 1
GCK glucokinase (hexokinase 4)
GCLC glutamate-cysteine ligase, catalytic subunit
GDF1 growth differentiation factor 1
GHR growth hormone receptor
GHRH growth hormone releasing hormone
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GJB1 gap junction protein, beta 1, 32kDa
GLA galactosidase, alpha
GLB1 galactosidase, beta 1
GLMP glycosylated lysosomal membrane protein
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNMT glycine N-methyltransferase
GOLM1 golgi membrane protein 1
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPBAR1 G protein-coupled bile acid receptor 1
GPER1 G protein-coupled estrogen receptor 1
GPI glucose-6-phosphate isomerase
GPR12 G protein-coupled receptor 12
GPR132 G protein-coupled receptor 132
GPRC6A G protein-coupled receptor, class C, group 6, member A
GPX7 glutathione peroxidase 7
GRB10 growth factor receptor-bound protein 10
GRB14 growth factor receptor-bound protein 14
GRN granulin
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSTZ1 glutathione S-transferase zeta 1
GTF2IRD1 GTF2I repeat domain containing 1
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GUCY2C guanylate cyclase 2C
GYS1 glycogen synthase 1 (muscle)
GYS2 glycogen synthase 2 (liver)
H2AFY H2A histone family, member Y
HABP2 hyaluronan binding protein 2
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAMP hepcidin antimicrobial peptide
HDAC3 histone deacetylase 3
HES1 hes family bHLH transcription factor 1
HEXA hexosaminidase A (alpha polypeptide)
HEXB hexosaminidase B (beta polypeptide)
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HHEX hematopoietically expressed homeobox
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HK1 hexokinase 1
HLX H2.0-like homeobox
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HPRT1 hypoxanthine phosphoribosyltransferase 1
HR hair growth associated
HRH1 histamine receptor H1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
HSPG2 heparan sulfate proteoglycan 2
HYAL1 hyaluronoglucosaminidase 1
HYAL2 hyaluronoglucosaminidase 2
ICMT isoprenylcysteine carboxyl methyltransferase
IDUA iduronidase, alpha-L-
IFITM1 interferon induced transmembrane protein 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFT88 intraflagellar transport 88
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2R insulin-like growth factor 2 receptor
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL12RB2 interleukin 12 receptor, beta 2
IL1R1 interleukin 1 receptor, type I
IL2 interleukin 2
IL22 interleukin 22
IL27RA interleukin 27 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
INHA inhibin, alpha
INS insulin
INSR insulin receptor
INVS inversin
IQGAP2 IQ motif containing GTPase activating protein 2
IREB2 iron-responsive element binding protein 2
IRF8 interferon regulatory factor 8
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JARID2 jumonji, AT rich interactive domain 2
JCHAIN joining chain of multimeric IgA and IgM
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
JUND jun D proto-oncogene
JUP junction plakoglobin
KAT6A K(lysine) acetyltransferase 6A
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KDM3A lysine (K)-specific demethylase 3A
KIFAP3 kinesin-associated protein 3
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLB klotho beta
KLF1 Kruppel-like factor 1 (erythroid)
KLF15 Kruppel-like factor 15
KLF2 Kruppel-like factor 2
KLF3 Kruppel-like factor 3 (basic)
KLF6 Kruppel-like factor 6
KMT2A lysine (K)-specific methyltransferase 2A
KMT2B lysine (K)-specific methyltransferase 2B
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LACTB2 lactamase, beta 2
LAMA4 laminin, alpha 4
LAT linker for activation of T cells
LBP lipopolysaccharide binding protein
LDHA lactate dehydrogenase A
LDLR low density lipoprotein receptor
LECT2 leukocyte cell-derived chemotaxin 2
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LEP leptin
LEPR leptin receptor
LGMN legumain
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LHX2 LIM homeobox 2
LIF leukemia inhibitory factor
LIG1 ligase I, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LIPA lipase A, lysosomal acid, cholesterol esterase
LIPE lipase, hormone-sensitive
LIPI lipase, member I
LMF1 lipase maturation factor 1
LPIN1 lipin 1
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LSR lipolysis stimulated lipoprotein receptor
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP1 latent transforming growth factor beta binding protein 1
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
LYZ lysozyme
MALRD1 MAM and LDL receptor class A domain containing 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MANBA mannosidase, beta A, lysosomal
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPK14 mitogen-activated protein kinase 14
MAPK6 mitogen-activated protein kinase 6
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK9 mitogen-activated protein kinase 9
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MARVELD2 MARVEL domain containing 2
MAT1A methionine adenosyltransferase I, alpha
MBD5 methyl-CpG binding domain protein 5
MBTD1 mbt domain containing 1
MC4R melanocortin 4 receptor
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MECP2 methyl CpG binding protein 2
MED1 mediator complex subunit 1
MEFV Mediterranean fever
MEG3 maternally expressed 3 (non-protein coding)
MEGF8 multiple EGF-like-domains 8
MEIS1 Meis homeobox 1
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MFSD2A major facilitator superfamily domain containing 2A
MFSD8 major facilitator superfamily domain containing 8
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MGLL monoglyceride lipase
MIR122 microRNA 122
MIR378A microRNA 378a
MKL2 MKL/myocardin-like 2
MKS1 Meckel syndrome, type 1
MLXIPL MLX interacting protein-like
MME membrane metallo-endopeptidase
MOGAT2 monoacylglycerol O-acyltransferase 2
MORF4L1 mortality factor 4 like 1
MPV17 MpV17 mitochondrial inner membrane protein
MPZL3 myelin protein zero-like 3
MRAP2 melanocortin 2 receptor accessory protein 2
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
MSTN myostatin
MSX1 msh homeobox 1
MTA2 metastasis associated 1 family, member 2
MTAP methylthioadenosine phosphorylase
MTF1 metal-regulatory transcription factor 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTSS1 metastasis suppressor 1
MTTP microsomal triglyceride transfer protein
MUC1 mucin 1, cell surface associated
MUT methylmalonyl CoA mutase
MYB v-myb avian myeloblastosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH10 myosin, heavy chain 10, non-muscle
NAGLU N-acetylglucosaminidase, alpha
NCF1 neutrophil cytosolic factor 1
NCKAP1L NCK-associated protein 1-like
NCOA3 nuclear receptor coactivator 3
NCOA5 nuclear receptor coactivator 5
NCOA6 nuclear receptor coactivator 6
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NDFIP1 Nedd4 family interacting protein 1
NEGR1 neuronal growth regulator 1
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEU1 sialidase 1 (lysosomal sialidase)
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFE2L1 nuclear factor, erythroid 2-like 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NGFR nerve growth factor receptor
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NLRP3 NLR family, pyrin domain containing 3
NME1 NME/NM23 nucleoside diphosphate kinase 1
NMU neuromedin U
NODAL nodal growth differentiation factor
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NOV nephroblastoma overexpressed
NPBWR1 neuropeptides B/W receptor 1
NPC1 Niemann-Pick disease, type C1
NPC1L1 NPC1-like 1
NPC2 Niemann-Pick disease, type C2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NPY5R neuropeptide Y receptor Y5
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OCA2 oculocutaneous albinism II
OMA1 OMA1 zinc metallopeptidase
ONECUT1 one cut homeobox 1
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
OTC ornithine carbamoyltransferase
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PANK1 pantothenate kinase 1
PAPPA2 pappalysin 2
PASK PAS domain containing serine/threonine kinase
PBRM1 polybromo 1
PBX1 pre-B-cell leukemia homeobox 1
PCCA propionyl CoA carboxylase, alpha polypeptide
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK9 proprotein convertase subtilisin/kexin type 9
PCTP phosphatidylcholine transfer protein
PDCD1 programmed cell death 1
PDGFB platelet-derived growth factor beta polypeptide
PDX1 pancreatic and duodenal homeobox 1
PDZK1 PDZ domain containing 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PEMT phosphatidylethanolamine N-methyltransferase
PEX1 peroxisomal biogenesis factor 1
PEX11A peroxisomal biogenesis factor 11 alpha
PEX11B peroxisomal biogenesis factor 11 beta
PEX13 peroxisomal biogenesis factor 13
PEX2 peroxisomal biogenesis factor 2
PEX5 peroxisomal biogenesis factor 5
PEX7 peroxisomal biogenesis factor 7
PHIP pleckstrin homology domain interacting protein
PHYH phytanoyl-CoA 2-hydroxylase
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PILRA paired immunoglobin-like type 2 receptor alpha
PITPNA phosphatidylinositol transfer protein, alpha
PITX2 paired-like homeodomain 2
PITX3 paired-like homeodomain 3
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G12B phospholipase A2, group XIIB
PLA2G15 phospholipase A2, group XV
PLA2G1B phospholipase A2, group IB (pancreas)
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
PLIN1 perilipin 1
PLIN2 perilipin 2
PLIN5 perilipin 5
PNLIP pancreatic lipase
PNPLA2 patatin-like phospholipase domain containing 2
PNRC2 proline-rich nuclear receptor coactivator 2
POLB polymerase (DNA directed), beta
POMC proopiomelanocortin
POR P450 (cytochrome) oxidoreductase
POU2F1 POU class 2 homeobox 1
POU3F2 POU class 3 homeobox 2
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1R15B protein phosphatase 1, regulatory subunit 15B
PPT1 palmitoyl-protein thioesterase 1
PPT2 palmitoyl-protein thioesterase 2
PRDX6 peroxiredoxin 6
PREP prolyl endopeptidase
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRF1 perforin 1 (pore forming protein)
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCD protein kinase C, delta
PRKCDBP protein kinase C, delta binding protein
PRKCI protein kinase C, iota
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PRLH prolactin releasing hormone
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PROX1 prospero homeobox 1
PSAP prosaposin
PTCD2 pentatricopeptide repeat domain 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRC protein tyrosine phosphatase, receptor type, C
PXMP2 peroxisomal membrane protein 2, 22kDa
RAD17 RAD17 homolog (S. pombe)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RB1 retinoblastoma 1
RB1CC1 RB1-inducible coiled-coil 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBL1 retinoblastoma-like 1
RBP1 retinol binding protein 1, cellular
RC3H1 ring finger and CCCH-type domains 1
RCAN2 regulator of calcineurin 2
RDH10 retinol dehydrogenase 10 (all-trans)
RDH16 retinol dehydrogenase 16 (all-trans)
RDX radixin
REG1B regenerating islet-derived 1 beta
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RETN resistin
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGN regucalcin
RHBDD3 rhomboid domain containing 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPGRIP1L RPGRIP1-like
RPS6 ribosomal protein S6
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RTN4RL1 reticulon 4 receptor-like 1
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RXRA retinoid X receptor, alpha
SAFB scaffold attachment factor B
SAMD4A sterile alpha motif domain containing 4A
SAT1 spermidine/spermine N1-acetyltransferase 1
SC5D sterol-C5-desaturase
SCARA5 scavenger receptor class A, member 5
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SCO2 SCO2 cytochrome c oxidase assembly protein
SCP2 sterol carrier protein 2
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELENBP1 selenium binding protein 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SENP1 SUMO1/sentrin specific peptidase 1
SEP15 15 kDa selenoprotein
SEPP1 selenoprotein P, plasma, 1
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERTAD2 SERTA domain containing 2
SESN2 sestrin 2
SFN stratifin
SGMS2 sphingomyelin synthase 2
SGSH N-sulfoglucosamine sulfohydrolase
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHROOM3 shroom family member 3
SIAH1 siah E3 ubiquitin protein ligase 1
SIK3 SIK family kinase 3
SIN3B SIN3 transcription regulator family member B
SIRPA signal-regulatory protein alpha
SIRT3 sirtuin 3
SIRT7 sirtuin 7
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC39A5 solute carrier family 39 (zinc transporter), member 5
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLIT3 slit homolog 3 (Drosophila)
SMAP1 small ArfGAP 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNORD50A small nucleolar RNA, C/D box 50A
SNORD50B small nucleolar RNA, C/D box 50B
SNX27 sorting nexin family member 27
SOAT1 sterol O-acyltransferase 1
SOAT2 sterol O-acyltransferase 2
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOX17 SRY (sex determining region Y)-box 17
SOX7 SRY (sex determining region Y)-box 7
SP3 Sp3 transcription factor
SPEN spen family transcriptional repressor
SPI1 Spi-1 proto-oncogene
SPP1 secreted phosphoprotein 1
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRA1 steroid receptor RNA activator 1
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SRSF10 serine/arginine-rich splicing factor 10
SSFA2 sperm specific antigen 2
STAB2 stabilin 2
STARD10 StAR-related lipid transfer (START) domain containing 10
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD4 StAR-related lipid transfer (START) domain containing 4
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT5B signal transducer and activator of transcription 5B
STEAP3 STEAP family member 3, metalloreductase
STEAP4 STEAP family member 4
STK11 serine/threonine kinase 11
STX2 syntaxin 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SUMF1 sulfatase modifying factor 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TACC3 transforming, acidic coiled-coil containing protein 3
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TBX3 T-box 3
TCEA1 transcription elongation factor A (SII), 1
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDG thymine-DNA glycosylase
TERF2IP telomeric repeat binding factor 2, interacting protein
TET2 tet methylcytosine dioxygenase 2
TFR2 transferrin receptor 2
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TH tyrosine hydroxylase
THBS1 thrombospondin 1
THEM4 thioesterase superfamily member 4
THEM5 thioesterase superfamily member 5
THRA thyroid hormone receptor, alpha
TICAM1 toll-like receptor adaptor molecule 1
TIMP3 TIMP metallopeptidase inhibitor 3
TK1 thymidine kinase 1, soluble
TK2 thymidine kinase 2, mitochondrial
TKT transketolase
TLL1 tolloid-like 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TMEM14C transmembrane protein 14C
TMEM67 transmembrane protein 67
TMOD3 tropomodulin 3 (ubiquitous)
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNIP1 TNFAIP3 interacting protein 1
TNNT3 troponin T type 3 (skeletal, fast)
TOP1MT topoisomerase (DNA) I, mitochondrial
TP53 tumor protein p53
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TREX1 three prime repair exonuclease 1
TRIB1 tribbles pseudokinase 1
TRIM24 tripartite motif containing 24
TRIM27 tripartite motif containing 27
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TTC7A tetratricopeptide repeat domain 7A
TUB tubby bipartite transcription factor
TWIST2 twist family bHLH transcription factor 2
TXNIP thioredoxin interacting protein
TXNRD2 thioredoxin reductase 2
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBC ubiquitin C
UCN3 urocortin 3
UNC93B1 unc-93 homolog B1 (C. elegans)
UROS uroporphyrinogen III synthase
UTS2 urotensin 2
VASN vasorin
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
VTI1B vesicle transport through interaction with t-SNAREs 1B
WASF1 WAS protein family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XBP1 X-box binding protein 1
XCL1 chemokine (C motif) ligand 1
XIRP2 xin actin binding repeat containing 2
XPA xeroderma pigmentosum, complementation group A
XYLT2 xylosyltransferase II
YBX1 Y box binding protein 1
ZDHHC13 zinc finger, DHHC-type containing 13
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPM1 zinc finger protein, FOG family member 1
ZFPM2 zinc finger protein, FOG family member 2
ZIC3 Zic family member 3